The effect of maternal hypothyroidism on the postnatal development of the pituitary–thyroid axis in albino rats: a histological, morphometric, and immunohistochemical study

2017 ◽  
Vol 2 (1) ◽  
pp. 79 ◽  
Author(s):  
AshrafE Bastwrous ◽  
MohamedR Shehata ◽  
DorreiaA Mohamed ◽  
ManalM. Samy El-Meligy
Keyword(s):  
Postnatal Development ◽  
Immunohistochemical Study ◽  
Albino Rats ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis

Postnatal development of brain TRH, serum TSH and thyroid hormones in the male and female rat

1986 ◽  
Vol 112 (1) ◽  
pp. 7-11 ◽  
Author(s):  
L. Gayo ◽  
B. Bonet ◽  
A. S. Herranz ◽  
R. Iglesias ◽  
M.J. Toro ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thyroid Hormones ◽  
Postnatal Development ◽  
Female Rat ◽  
Male And Female ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis ◽  
The Central Nervous System ◽  
Serum Tsh

Abstract. The postnatal development of immunoreactive TRH in the central nervous system (CNS), serum TSH and thyroid hormones was studied in both male and female normal rats. While in most structures of the CNS, TRH increased until day 20–30, serum TSH values peaked at day 15 as did T4. Significant differences were also obtained between both sexes in these parameters. These data further support the fact that pituitary-thyroid axis maturation is independent of brain TRH.

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