Postnatal development of brain TRH, serum TSH and thyroid hormones in the male and female rat

1986 ◽  
Vol 112 (1) ◽  
pp. 7-11 ◽  
Author(s):  
L. Gayo ◽  
B. Bonet ◽  
A. S. Herranz ◽  
R. Iglesias ◽  
M.J. Toro ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thyroid Hormones ◽  
Postnatal Development ◽  
Female Rat ◽  
Male And Female ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis ◽  
The Central Nervous System ◽  
Serum Tsh

Abstract. The postnatal development of immunoreactive TRH in the central nervous system (CNS), serum TSH and thyroid hormones was studied in both male and female normal rats. While in most structures of the CNS, TRH increased until day 20–30, serum TSH values peaked at day 15 as did T4. Significant differences were also obtained between both sexes in these parameters. These data further support the fact that pituitary-thyroid axis maturation is independent of brain TRH.

scholarly journals Psychiatric Symptoms due to Thyroid Disease in a Female Adolescent

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Nelly Capetillo-Ventura ◽  
Inmaculada Baeza
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thyroid Hormone ◽  
Psychiatric Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Female Adolescent ◽  
Normal Functioning ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis ◽  
The Central Nervous System

The hypothalamic-pituitary-thyroid axis is involved in the production of thyroid hormone which is needed to maintain the normal functioning of various organs and systems, including the central nervous system. This study reports a case of hypothyroidism in a fifteen-year-old female adolescent who was attended for psychiatric symptoms. This case reveals the importance of evaluating thyroid function in children and adolescents with neuropsychiatric symptoms.

GAP-43 gene expression during postnatal development in the central nervous system of macaque monkey

1994 ◽  
Vol 19 ◽  
pp. S121 ◽  
Author(s):  
Takao Oishi ◽  
Keiji Matsuda ◽  
Noriyuki Higo ◽  
Yumiko Umino ◽  
Motoharu Hayashi
Keyword(s):  
Gene Expression ◽  
Central Nervous System ◽  
Nervous System ◽  
Postnatal Development ◽  
Macaque Monkey ◽  
The Central Nervous System

scholarly journals The pituitary-thyroid axis in healthy men living under subarctic climatological conditions

2001 ◽  
Vol 169 (1) ◽  
pp. 195-203 ◽  
Author(s):  
J Hassi ◽  
K Sikkila ◽  
A Ruokonen ◽  
J Leppaluoto
Keyword(s):  
Thyroid Hormones ◽  
Climatic Factors ◽  
Feedback Mechanism ◽  
Free Triiodothyronine ◽  
Serum Free ◽  
Healthy Men ◽  
Non Invasive ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis ◽  
Serum Tsh

In order to evaluate the effects of climatic factors on the secretion of thyroid hormones and TSH in a high latitude population, we have taken serum and urine samples from 20 healthy men from northern Finland (67 degrees -68 degrees N) every 2 months for a period of 14 months. Serum free triiodothyronine (T(3)) levels were lower in February than in August (3.9 vs 4.4 pmol/l, P<0.05) and TSH levels were higher in December than during other months (2.1 vs 1.5-1.7 mU/l, P<0.01). Serum total and free thyroxine (T(4)), total T(3) and reverse T(3) levels and urinary T(4) levels were unchanged. Urinary T(3) levels were significantly higher in winter than in summer. Serum free T(3) correlated highly significantly with the outdoor temperature integrated backwards weekly for 7-56 days (r=0.26 for 1-56 days) from the day when the blood samples were taken. Serum TSH did not show any significant correlation with the thyroid hormones or with the integrated temperature of the previous days, but it did show an inverse and significant correlation (r=-0.31) with the ambient luminosity integrated backwards for 7 days from the day when the blood sample was taken. The gradually increasing correlation between outdoor temperatures and serum free T(3) suggests that the disposal of thyroid hormones is accelerated in winter, leading to low serum free T(3) levels and a high urinary free T(3) excretion. Since there was no correlation between thyroid hormones and serum TSH, the feedback mechanism between TSH and thyroid hormones may not be the only contributing factor, and other factors such as ambient luminosity may at least partly determine serum TSH in these conditions. Also urinary free T(3) appears to be a novel and non-invasive indicator for thyroid physiology.

scholarly journals Glioendocrine System: Effects of Thyroid Hormones in Glia and their Functions in the Central Nervous System

2020 ◽  
Vol 3 (1) ◽  
pp. 1-11
Author(s):  
Mami Noda
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cognitive Impairment ◽  
Thyroid Hormones ◽  
Glial Cells ◽  
Endocrine System ◽  
Cell Types ◽  
Development And Differentiation ◽  
The Central Nervous System ◽  
And Function

AbstractGlial cells play a significant role in the link between the endocrine and nervous systems. Among hormones, thyroid hormones (THs) are critical for the regulation of development and differentiation of neurons and glial cells, and hence for development and function of the central nervous system (CNS). THs are transported into the CNS, metabolized in astrocytes and affect various cell types in the CNS including astrocyte itself. Since 3,3’,5-triiodo-L-thyronine (T3) is apparently released from astrocytes in the CNS, it is a typical example of glia-endocrine system.The prevalence of thyroid disorders increases with age. Both hypothyroidism and hyperthyroidism are reported to increase the risk of cognitive impairment or Alzheimer’s disease (AD). Therefore, understanding the neuroglial effects of THs may help to solve the problem why hypothyroidism or hyperthyroidism may cause mental disorders or become a risk factor for cognitive impairment. In this review, THs are focused among wide variety of hormones related to brain function, and recent advancement in glioendocrine system is described.

1624: A Model to Assess the Sensory Feedback From the External Genitalia to the Central Nervous System in Female Rat

2004 ◽  
Vol 171 (4S) ◽  
pp. 429-429
Author(s):  
François Giuliano ◽  
Kamal Rahmouni ◽  
Laurent Alexandre ◽  
Stéphane Droupy ◽  
Jacques Bernabé
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sensory Feedback ◽  
External Genitalia ◽  
Female Rat ◽  
The Central Nervous System
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