scholarly journals Preexisting right ventricular systolic dysfunction in high-risk patients undergoing non.emergent open abdominal surgery: A retrospective cohort study

2021 ◽  
Vol 24 (1) ◽  
pp. 62
Author(s):  
Jody Chou ◽  
Michael Ma ◽  
Maryte Gylys ◽  
Nicolas Salvatierra ◽  
Robert Kim ◽  
...  
2019 ◽  
Author(s):  
Jody Chou ◽  
Michael Ma ◽  
Maryte Gylys ◽  
Nicolas Salvatierra ◽  
Robert Kim ◽  
...  

Abstract Background: The prognostic value of right ventricular systolic dysfunction in high-risk patients undergoing non-emergent open abdominal surgery is unknown. Here, we aim to evaluate whether presence of preexisting right ventricular systolic dysfunction in this surgical cohort is independently associated with higher incidence of postoperative major adverse cardiac events and all-cause in-hospital mortality. Methods: This is a single-centered retrospective study. Patients identified as American Society Anesthesiology Classification III and IV who had a preoperative echocardiogram within 1 year of undergoing non-emergent open abdominal surgery between January 2010 and May 2017 were included in the study. Incidence of postoperative major cardiac adverse events and all-cause in-hospital mortality were collected. Multivariable logistic regression was performed in a step-wise manner to identify independent association between preexisting right ventricular dysfunction with outcomes of interest. Results: Preexisting right ventricular systolic dysfunction was not associated with postoperative major adverse cardiac events (p=0.26). However, there was a strong association between preexisting right ventricular systolic dysfunction and all-cause in-hospital mortality (p=0.00094). After multivariate analysis, preexisting right ventricular systolic dysfunction continued to be an independent risk factor for all-cause in-hospital mortality with an odds ratio of 18.9 (95% CI: 1.8-201.7; p=0.015). Conclusion: In this retrospective study of high-risk patients undergoing nonemergent open abdominal surgery, preexisting right ventricular systolic dysfunction was found to have a strong association with all-cause in-hospital mortality. Keywords: Preexisting right ventricular systolic dysfunction, open abdominal surgery, major adverse cardiac events, mortality.


Author(s):  
M. (Mayke) de Klerk ◽  
D.H. (Henri) van Dalen ◽  
L.M.W. (Lenny) Nahar-van Venrooij ◽  
W.J.H.J. (Jeroen) Meijerink ◽  
E.G.G. (Emiel) Verdaasdonk

2019 ◽  
Vol 33 (4) ◽  
pp. 457-461
Author(s):  
Zlatana Nenova ◽  
John Hotchkiss

Background: Chronic kidney disease palliative care guidelines would benefit from more diverse and objectively defined health status measures. Aim: The aim is to identify high-risk patients from administrative data and facilitate timely and uniform palliative care involvement. Design: It is a retrospective cohort study. Setting/participants: In total, 45,368 Veterans, with chronic kidney disease Stage 3, 4, or 5, were monitored for up to 6 years and categorized into three groups, based on whether they died, started dialysis, or avoided both outcomes. Results: Patient’s appointment utilization was a significant predictor for both outcomes. It separated individuals into low, medium, and high appointment utilizers. Among the low appointment utilizers, the risk of death did not change significantly, while the risk of dialysis increased. Medium appointment utilizers had a stable risk of death and a decreasing risk of dialysis. Significant appointment utilization (above 31 visits during the baseline year) helped high-risk patients avoid both outcomes of interest—death and dialysis. Conclusion: Our model could justify the creation of a novel palliative care introduction trigger, as patients with medium demand for care may benefit from additional palliative care evaluation. The trigger could facilitate the uniformization of conservative treatment preparations. It could prompt messages to a managing physician when a patient crosses the threshold between low and medium appointment utilization. It may also aid in system-level policy development. Furthermore, our results highlight the benefit of significant appointment utilization among high-risk patients.


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