Clinical, biochemical, and phenotype profile of the patients newly diagnosed with polycystic ovarian syndrome

Polycystic Ovarian Syndrome (PCOS) is a common disease exclusively seen in women of reproductive age group. World Health Organization reports that Polycystic Ovarian Syndrome approximately affects 5-10% of the reproductive female population worldwide. Women with PCOS have chronic inflammation. This in turn leads to increased incidence of non-communicable diseases like cardiovascular disease and diabetes2. Chronic inflammation in PCOS patients can be identified using serum markers such as C - reactive protein [CRP], Interleukin-6 [IL-6] and Interleukin-18 [IL-18].So the main objective of the study was to assess the status of inflammation in patients with Polycystic Ovary Syndrome (PCOS) and to assess the influence of drugs prescribed for PCOS on inflammation. Patients were divided into three groups as healthy volunteers, newly diagnosed PCOS patients, already on treatment patients for PCOS. High sensitivity CRP (hs-CRP), IL-6 and IL-18 were assessed. There was an increase in the hs-CRP, IL-6 and IL-18 compared to healthy volunteers in both newly diagnosed and already diagnosed groups. But there was no statistical significance (hs-CRP=0.975, IL-6=0.746, IL-18 = 0.148) between them. The mean value has decreased in the already on treatment group as duration of treatment increases. There was no statistical significance between them. There was an inversely proportional relationship between the mean values of inflammatory markers and duration of treatment.

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Evaluation of periodontal health among patients with polycystic ovarian syndrome a cross sectional study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20211503 ◽

2021 ◽

Vol 10 (5) ◽

pp. 1869

Author(s):

Rohini Subbiah ◽

Menaka Sathish ◽

Madankumar Parangimalai Diwakar

Keyword(s):

Medical Treatment ◽

Polycystic Ovarian Syndrome ◽

Cross Sectional Study ◽

The Body ◽

Newly Diagnosed ◽

Sectional Study ◽

Periodontal Health ◽

Cross Sectional ◽

Periodontal Inflammation ◽

Ovarian Syndrome

Background: Polycystic Ovarian Syndrome (PCOS) and periodontal disease are common disorders associated with diabetes and cardiometabolic risk. Recently, some studies have revealed the effect of polycystic ovary syndrome (PCOS) on gingival inflammation. This cross-sectional study attempts to assess the periodontal health status and systemic inflammation of women receiving medical treatment for PCOS and women newly diagnosed with PCOS.Methods: A total of 60 participants comprising 30 newly diagnosed patients with PCOS (PCOS-N), 30 patients with PCOS on medical treatment (PCOS-MT) were examined. Periodontal parameters were recorded and compared.Results: This study resulted that the women with newly diagnosed PCOS may have increased prevalence and likelihood for periodontitis, with higher measures of periodontal inflammation and breakdown than those on medical treatment for PCOS.Conclusions: In PCOS females, there is an alteration of various hormone levels in the body. These hormones might act on gingival cells by changing the effectiveness of the epithelial barrier to bacterial injury or by affecting the collagen maintenance and repair.

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Abstract #782247: Polycystic Ovarian Syndrome: Variation in Diagnosis and Management

Endocrine Practice ◽

10.1016/s1530-891x(20)39422-2 ◽

2020 ◽

Vol 26 ◽

pp. 178

Author(s):

S.M. Ashrafuzzaman

Keyword(s):

Polycystic Ovarian Syndrome ◽

Diagnosis And Management ◽

Ovarian Syndrome

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Abstract #515: Effects of Bariatric Surgery on Metabolic Syndrome in Obese Women with Polycystic Ovarian Syndrome

Endocrine Practice ◽

10.1016/s1530-891x(20)45073-6 ◽

2016 ◽

Vol 22 ◽

pp. 124

Author(s):

Mc Anto Antony ◽

Shannon Sullivan

Keyword(s):

Bariatric Surgery ◽

Metabolic Syndrome ◽

Polycystic Ovarian Syndrome ◽

Obese Women ◽

Ovarian Syndrome

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ULTRASONOGRAPHIC FOLLOW-UP OF ANTIANDROGENIC THERAPY IN POLYCYSTIC OVARIAN SYNDROME

Ultraschall in der Medizin - European Journal of Ultrasound ◽

10.1055/s-2005-917591 ◽

2005 ◽

Vol 26 (S 1) ◽

Author(s):

D Pelinescu-Onciul ◽

R Radulescu-Botica

Keyword(s):

Polycystic Ovarian Syndrome ◽

Ovarian Syndrome ◽

Antiandrogenic Therapy

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Characteristics of Polycystic Ovarian Syndrome in Sub-fertile Woman Attending to GOPD in ShSMCH

Journal of Shaheed Suhrawardy Medical College ◽

10.3329/jssmc.v11i1.43173 ◽

2019 ◽

Vol 11 (1) ◽

pp. 17-23

Author(s):

Jinnat Ara Islam ◽

Fatema Ashraf ◽

Eva Rani Nandi

Keyword(s):

Polycystic Ovarian Syndrome ◽

Polycystic Ovaries ◽

Cross Sectional ◽

Medical College ◽

Appropriate Treatment ◽

Pcos Group ◽

Symptom Complex ◽

Ovarian Syndrome ◽

Selection Of ◽

Fertile Women

Background: Polycystic ovarian syndrome (PCOS) is a condition characterized by menstrual abnormalities (oligo/amenorrhea) and clinical or biochemical features of hyperandrogenism and may manifest at any age. It is a common cause of female subfertility. All the dimensions of PCOS have not been yet completely explored. Methods: It was a cross sectional comparative study carried out at-GOPD of Shaheed Suhrawardy Medical College & Hospital from January, 2016 to December 2016 on 162 subfertile women. Among them 54 were PCOS group and 108 were non PCOS group. PCOS was diagnosed by (Rotterdam criteria 2003) (i) Oligo or anovulation (ii) hyperandrogenism (iii) Polycystic ovaries. Study was done to evaluate and compare the demographic characteristics, clinical, biochemical and ultrasoundgraphic features of sub-fertile women with and without PCOS. Results: A total of 162 sub-fertile women aged 16-36 years. Mean age was 29.5±5.4. There were significant differences between the two groups in terms of (oligo/amenorrhea), hirsutism, WHR and ovarian ultrasound features. There were no significant differences between two groups in correlations between the level of obesity with the incidence of anovulation, hyperandrogenism or with hormonal features. Conclusion: PCOS is one of the important factors causing Infertility. It is an ill-defined symptom complex needed due attention. There is a need to increase awareness regarding. The clinical features of PCOS are heterogenous thus can be investigated accordingly of selection of appropriate treatment modality. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 17-23

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