scholarly journals Total intravenous anaesthesia with tumescent infiltration anaesthesia without definitive airway for early excision and skin grafting in a major burn - A prospective observational study

2020 ◽  
Vol 64 (7) ◽  
pp. 611
Author(s):  
NishaM Jain ◽  
SwetaV Salgaonkar ◽  
SachinP Pawar
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Skin Grafting ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Major Burn

scholarly journals A prospective observational study of follicular unit excision grafting for the management of stable vitiligo

2019 ◽  
Vol 5 (4) ◽  
pp. 706
Author(s):  
Raj Kumar ◽  
Sunil Kumar Prajapati ◽  
Santosh Kumar Singh ◽  
Anil Kumar Gupta
Keyword(s):  
Observational Study ◽  
Medical Therapy ◽  
Prospective Observational Study ◽  
Social Stigma ◽  
Skin Grafting ◽  
Cost Effective ◽  
Effective Management ◽  
Color Match ◽  
Follicular Unit ◽  
Over Time

<p class="abstract"><strong>Background:</strong> Vitiligo is a common acquired idiopathic and often, familial hypomelanosis, which is characterized by pale white macules that enlarges centrifugally over time. In India, vitiligo is associated with marked social stigma, thus demanding its effective management. Stable vitiligo lesions known to be relatively refractory medical therapy require surgical therapies like skin grafting or grafting of invitro cultured and non-cultured melanocytes or follicular unit excision (FUE) grafting.</p><p class="abstract"><strong>Methods:</strong> A prospective observational study was done on patients of stable vitiligo. A total of 20 patients were enrolled and underwent FUE grafting for study of effectiveness and complication.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 20 patients of stable vitiligo were studied with or without leukotrichia in which good to excellent response was seen in 13 (65%), fair in 6 (30%) and poor in 1 (5%) patients.</p><p class="abstract"><strong>Conclusions:</strong> FUE is a superior and upcoming methodology which is cost effective, reliable, less disfiguring, very low morbidity and results in good color match in patients with stable vitiligo.</p>

scholarly journals A prospective observational study on prevention of contractures of upper limb following burn

2020 ◽  
Vol 7 (5) ◽  
pp. 1431
Author(s):  
Akash Gupta ◽  
Sanjay Pandey ◽  
Sandeep Kansal ◽  
Atul Jain
Keyword(s):  
Observational Study ◽  
Surgical Management ◽  
Upper Limb ◽  
Prospective Observational Study ◽  
Preventive Measures ◽  
Skin Grafting ◽  
North India ◽  
Medical College ◽  
Mobile Part ◽  
Burn Contractures

Background: Over 1 lakh people are affected by burn every year in India and 20 thousands of them die per year. Post burn contracture is a common sequele occurring after burn. Upper limb contractures are also occurring more commonly because it is most mobile part of body and likely to be involved in burn. There are many studies on management of post burn contractures but literature about prevention of contracture is little, hence this study was conducted. The aim of this study was to recognise various preventive measures to prevent post burn contractures of upper extremity.Methods: This study was conducted in NSCBM Subharti Medical College and Hospital located in Meerut (North India) from October 2012 to October 2014 in Department of Surgery. It was a prospective observational study consisted of 80 cases who presented as acute burn of upper limb admitted in the hospital.Results: In our study early excision with skin grafting was done in 20 patients (25%) while delayed skin grafting was done in 25 patients (31%) while 35 patients (44%) were managed conservatively. In our study 20 patients reported back with a post burn contracture. The reason found was non-compliance to antideformity splint and physiotherapy.Conclusions: Early surgical management of deep burns, physiotherapy, anti-deformity position and proper splintage can significantly reduce the development of post burn contracture.

C1 Esterase Inhibitor Activity Is Reduced in the Acute Phase Following Burn Injury: A Prospective Observational Study

2019 ◽  
Vol 40 (6) ◽  
pp. 893-899
Author(s):  
Hiroshi Matsuura ◽  
Akinori Osuka ◽  
Tomoya Hirose ◽  
Hiroshi Ogura ◽  
Masashi Ueyama ◽  
...  
Keyword(s):  
Observational Study ◽  
Vascular Permeability ◽  
Acute Phase ◽  
Prospective Observational Study ◽  
Burn Injury ◽  
Burn Patients ◽  
Inhibitor Activity ◽  
C1 Esterase Inhibitor ◽  
Major Burn ◽  
Esterase Inhibitor

AbstractHereditary angioedema has been attributed to an inherited deficiency of C1 esterase inhibitor that increases vascular permeability. The role of C1 esterase inhibitor in burn patients has not been described previously. In this study, we attempted to identify the relationship between serial changes of C1 esterase inhibitor activity and the clinical course in major burn patients. This study was a single-center, prospective, observational study. C1 esterase inhibitor activity values were serially examined in major burn patients admitted into the burn center from April 2014 to December 2016. Inclusion criteria were age ≥16 years old and %TBSA burned ≥20%. This study included 38 patients with major burn. C1 esterase inhibitor activity after burn dropped acutely on days 1 and 2 but increased immediately until days 3 to 5, after which it continued to gradually increase to above the reference value. C1 esterase inhibitor activity on admission showed significant inverse correlation with the volume of infusion per body weight required in the first 24 hours after injury and %TBSA burned (r = −0.405, P = 0.01; r = −0.375, P = 0.02, respectively). C1 esterase inhibitor activity on admission was significantly lower in the nonsurvivors than in the survivors during the 28-day evaluation period (59% vs 90%, P = 0.01). These findings suggest that C1 esterase inhibitor may play a critical role in regulating vascular permeability in the acute phase following the burn injury.

Prospective observational study comparing burn surgeons’ estimations of wound healing after skin grafting to photo-assisted methods

Burns ◽  
2019 ◽  
Vol 45 (7) ◽  
pp. 1562-1570 ◽  
Author(s):  
K.S. Koetsier ◽  
J.N. Wong ◽  
L.A. Muffley ◽  
G.J. Carrougher ◽  
T.N. Pham ◽  
...  
Keyword(s):  
Wound Healing ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Skin Grafting

Is major burn injury associated with coagulopathy? The value of thrombelastometry in the detection of coagulopathy in major burn injury: A prospective observational study

2020 ◽  
Vol 76 (2) ◽  
pp. 299-308
Author(s):  
Daniel Lonic ◽  
Paul I. Heidekrueger ◽  
Talia Bosselmann ◽  
P. Niclas Broer ◽  
Ralph Gertler ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Burn Injury ◽  
Total Body Surface Area ◽  
Initial Assessment ◽  
Burn Patients ◽  
Major Burn ◽  
Complex Picture ◽  
Coagulation Status ◽  
Burn Disease

BACKGRUND: The coagulation status of burn patients is generally impaired and is a major factor of the deteriorating burn patients’ overall situation. In trauma and other patient groups, the differential diagnosis of coagulation impairment has been largely improved by the use of rotational thromboelastometry (ROTEM®). The aim of this prospective observational study was the differentiated observation of coagulopathy in severely burned patients using standard parameters and ROTEM® thrombelastometry during the relevant stages of burn disease. PATIENTS AND METHODS: Twelve patients that sustained at least 20% third degree burns of total body surface area (TBSA) were included in the study. Standard and ROTEM® coagulation analyses were performed on admission and then twice daily during the first 14 days following burn trauma. RESULTS: Although the initial assessment of DIC was similar for both standard labs and ROTEM® measurements, more patients were detected to be in a state of worsening coagulation status for a longer time in ROTEM® than in standard measurements. In addition, one patient was rated in to be in decompensated DIC for 3 days according to ROTEM® measurements, while no patient was rated to be in a decompensated DIC based on standard parameters. CONCLUSION: This study points towards a more complex picture and higher occurrence of DIC in burn patients when thrombelastometric measurements like ROTEM® are taken into account in addition to standard coagulation parameters.

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