scholarly journals Contemplate enteroviral etiology: Not all neonatal sepsis syndromes are bacterial

2021 ◽  
Vol 8 (1) ◽  
pp. 33
Author(s):  
Femitha Pournami ◽  
MandyaKrishnappa Alok Kumar ◽  
Anand Nandakumar ◽  
Jyothi Prabhakar ◽  
Naveen Jain
Keyword(s):  
Neonatal Sepsis

Human Parechovirus Encephalitis As an Important Differential Diagnosis of White Matter Lesions in Neonatal Sepsis-Like Illness

2014 ◽  
Vol 45 (S 01) ◽  
Author(s):  
L. Freudenberg ◽  
S. Brenner ◽  
G. Hahn ◽  
M. van der Knaap ◽  
M. Smitka ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
White Matter ◽  
Neonatal Sepsis ◽  
White Matter Lesions ◽  
Human Parechovirus ◽  
Important Differential Diagnosis

Diagnosis of neonatal sepsis in low resource settings: C-reactive protein or procalcitonin?

2016 ◽  
Vol 03 (02) ◽  
pp. 079-083
Author(s):  
Lawrence Mbuagbaw ◽  
Francisca Monebenimp ◽  
Bolaji Obadeyi ◽  
Grace Bissohong ◽  
Marie-Thérèse Obama ◽  
...  
Keyword(s):  
Neonatal Sepsis ◽  
C Reactive Protein ◽  
Low Resource Settings ◽  
Low Resource ◽  
Reactive Protein

NEONATAL SEPSIS AND IDENTIFICATION OF RISK FACTORS: STUDY IN AVBRH HOSPITAL SAWANGI

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pramod P. Singhavi
Keyword(s):  
Risk Factors ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Late Onset ◽  
Signs And Symptoms ◽  
Premature Rupture ◽  
Maternal Risk ◽  
Late Onset Sepsis ◽  
Early Onset Sepsis ◽  
Meconium Stained Amniotic Fluid

Introduction: India has the highest incidence of clinical sepsis i.e.17,000/ 1,00,000 live births. In Neonatal sepsis septicaemia, pneumonia, meningitis, osteomyelitis, arthritis and urinary tract infections can be included. Mortality in the neonatal period each year account for 41% (3.6 million) of all deaths in children under 5 years and most of these deaths occur in low income countries and about one million of these deaths are due to infectious causes including neonatal sepsis, meningitis, and pneumonia. In early onset neonatal sepsis (EOS) Clinical features are non-specific and are inefficient for identifying neonates with early-onset sepsis. Culture results take up to 48 hours and may give false-positive or low-yield results because of the antenatal antibiotic exposure. Reviews of risk factors has been used globally to guide the development of management guidelines for neonatal sepsis, and it is similarly recommended that such evidence be used to inform guideline development for management of neonatal sepsis. Material and Methods: This study was carried out using institution based cross section study . The total number neonates admitted in the hospital in given study period was 644, of which 234 were diagnosed for neonatal sepsis by the treating pediatrician based on the signs and symptoms during admission. The data was collected: Sociodemographic characteristics; maternal information; and neonatal information for neonatal sepsis like neonatal age on admission, sex, gestational age, birth weight, crying immediately at birth, and resuscitation at birth. Results: Out of 644 neonates admitted 234 (36.34%) were diagnosed for neonatal sepsis by the paediatrician based on the signs and symptoms during admission. Of the 234 neonates, 189 (80.77%) infants were in the age range of 0 to 7 days (Early onset sepsis) while 45 (19.23%) were aged between 8 and 28 days (Late onset sepsis). Male to female ratio in our study was 53.8% and 46% respectively. Out of total 126 male neonates 91(72.2%) were having early onset sepsis while 35 (27.8%) were late onset type. Out of total 108 female neonates 89(82.4%) were having early onset sepsis while 19 (17.6%) were late onset type. Maternal risk factors were identified in 103(57.2%) of early onset sepsis cases while in late onset sepsis cases were 11(20.4%). Foul smelling liquor in early onset sepsis and in late onset sepsis was 10(5.56%) and 2 (3.70%) respectively. In early onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 21(11.67%), 19 (10.56%), 20(11.11%) and 33 (18.33%) cases respectively. In late onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 2 (3.70%), 1(1.85%), 3 (5.56%) and 3 (5.56%) cases respectively. Conclusion: Maternal risk identification may help in the early identification and empirical antibiotic treatment in neonatal sepsis and thus mortality and morbidity can be reduced.

The Promising Rule of Neutrophil CD64 As an Early Diagnostic and Prognostic Marker in Neonatal Sepsis

PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 457A-457A
Author(s):  
Heba E. Ossman ◽  
Shreen A. El-Masry ◽  
Nour M. Abdel Aal ◽  
Amira M. Mokhtar
Keyword(s):  
Prognostic Marker ◽  
Neonatal Sepsis ◽  
Neutrophil Cd64 ◽  
Early Diagnostic

The Promising Rule of Neutrophil CD64 As an Early Diagnostic and Prognostic Marker in Neonatal Sepsis

2017 ◽  
Author(s):  
Heba E. Ossman ◽  
Shreen A. El-Masry ◽  
Nour M. Abdel Aal ◽  
Amira M. Mokhtar
Keyword(s):  
Prognostic Marker ◽  
Neonatal Sepsis ◽  
Neutrophil Cd64 ◽  
Early Diagnostic

Assessment of serum interleukin-6 with a rapid test. The diagnosis of neonatal sepsis can be established or ruled out

2007 ◽  
Vol 148 (34) ◽  
pp. 1609-1614 ◽  
Author(s):  
Éva Görbe ◽  
Judit Jeager ◽  
Bálint Nagy ◽  
Ágnes Harmath ◽  
Erik Hauzman ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Neonatal Sepsis ◽  
Software Package ◽  
Rapid Test ◽  
Statistical Software

Bevezetés: A neonatális szepszis mortalitása magas, és koraszülöttek esetén a szepszis rizikója emelkedik a születési súly csökkenésével. Anyag és módszer: A szerzők gyorsteszt segítségével 12 érett újszülött és 60 igen kis súlyú (VLBW) koraszülött interleukin-6-vérszintjét határozták meg a C-reaktív protein vizsgálatával egyidejűleg, akiket a Semmelweis Egyetem I. Számú Szülészeti és Nőgyógyászati Klinikájának Neonatális Intenzív Centrumában kezeltek 2005-ben és 2006-ban. A szérum-IL-6 meghatározása gyorsteszt segítségével történt (Milenia Quickline IL-6, PicoScan system). Eredmények: Vizsgálataikban a szérum-interleukin-6- és CRP-meghatározás korrelált. A szérum-IL-6-meghatározás szenzitivitása a CRP-értékkel együtt az általuk vizsgált betegcsoportban 100% volt, álnegatív eset nem fordult elő. A vizsgálat pozitív prediktív értéke 93%. Adataikat Mann–Whitney-teszt segítségével analizálták (SPSS Statistical Software Package, Chicago, IL, USA). Szignifikáns különbség volt az igazolt szepszis és az infekciós betegcsoport IL-6-értékei között ( p = 0,048), valamint az infekciós és nem infekciós csoport interleukin-6-értékei között ( p < 0,005). Következtetések: Az igen kis súlyúak nem specifikus infekciós tünetekhez hasonló reakcióit értékelve, a szeptikus és nem infekciós esetek elkülönítése a neonatális morbiditás és mortalitás csökkentése érdekében is fontos szempont, a költségek csökkentésével egyidejűleg.

C1-ESTERASE INHIBITOR: APPROACHES TO RATIONAL PHARMACOTHERAPY OF NEONATAL SEPSIS

2019 ◽  
Vol 98 (3) ◽  
pp. 188-194
Author(s):  
A.P. Prodeus ◽  
◽  
M.V. Ustinova ◽  
A.U. Lekmanov ◽  
N.V. Kudryashov ◽  
...  
Keyword(s):  
Neonatal Sepsis ◽  
Rational Pharmacotherapy ◽  
C1 Esterase Inhibitor ◽  
Esterase Inhibitor
Sign in / Sign up

Export Citation Format

Share Document