scholarly journals Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre

2018 ◽  
Vol 22 (5) ◽  
pp. 361-363
Author(s):  
Mohini Yadav ◽  
Gauri Chauhan ◽  
A. Bhardwaj ◽  
P. Sharma
Keyword(s):  
Mechanical Ventilation ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre

scholarly journals Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study

Infection ◽  
2021 ◽  
Author(s):  
Charlotte Thibeault ◽  
◽  
Barbara Mühlemann ◽  
Elisa T. Helbig ◽  
Mirja Mittermaier ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Observational Study ◽  
Median Duration ◽  
Prospective Observational Study ◽  
Invasive Mechanical Ventilation ◽  
Tertiary Care ◽  
Detailed Knowledge ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Duration Of Symptoms

Abstract Purpose Adequate patient allocation is pivotal for optimal resource management in strained healthcare systems, and requires detailed knowledge of clinical and virological disease trajectories. The purpose of this work was to identify risk factors associated with need for invasive mechanical ventilation (IMV), to analyse viral kinetics in patients with and without IMV and to provide a comprehensive description of clinical course. Methods A cohort of 168 hospitalised adult COVID-19 patients enrolled in a prospective observational study at a large European tertiary care centre was analysed. Results Forty-four per cent (71/161) of patients required invasive mechanical ventilation (IMV). Shorter duration of symptoms before admission (aOR 1.22 per day less, 95% CI 1.10–1.37, p < 0.01) and history of hypertension (aOR 5.55, 95% CI 2.00–16.82, p < 0.01) were associated with need for IMV. Patients on IMV had higher maximal concentrations, slower decline rates, and longer shedding of SARS-CoV-2 than non-IMV patients (33 days, IQR 26–46.75, vs 18 days, IQR 16–46.75, respectively, p < 0.01). Median duration of hospitalisation was 9 days (IQR 6–15.5) for non-IMV and 49.5 days (IQR 36.8–82.5) for IMV patients. Conclusions Our results indicate a short duration of symptoms before admission as a risk factor for severe disease that merits further investigation and different viral load kinetics in severely affected patients. Median duration of hospitalisation of IMV patients was longer than described for acute respiratory distress syndrome unrelated to COVID-19.

scholarly journals Incidence of ventilator associated pneumonia and its risk factors

2016 ◽  
Vol 1 (3) ◽  
pp. 44
Author(s):  
Kavitha Chandran C ◽  
Sujith Kumar R ◽  
Sujamol Scaria
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Cause Of Death ◽  
Tertiary Care ◽  
Diagnostic Methods ◽  
Ventilator Associated Pneumonia ◽  
Care Centre ◽  
Tertiary Care Centre

Hospitals are intended to heal the sick; but they are also sources of infection. Ironically, the advances in medicine are partly responsible for the fact that today; hospital infections are the leading cause of death worldwide. Newer technology and latest surgical and medical diagnostic methods and treatment procedures have increased the number of invasive techniques leading to higher chances of nosocomial infection. Pneumonia is the leading cause of death due to nosocomial infections. Intubation & mechanical ventilation greatly increases the risk for ventilator-associated pneumonia (VAP). In developing country like India, such hospital-acquired infections have a significant impact on patient’s morbidity, mortality, hospital stay and on financial concerns of the patient, hospital and community. The present investigation was aimed to determine the incidence of ventilator associated pneumonia in the neurosurgery intensive care unit of a tertiary care centre and to determine the risk factors of ventilator associated pneumonia. A total of 30 samples belonging to the age group of 15 to 75 years who where on mechanical ventilator for more than 48 hours in the neurosurgery intensive care unit of a tertiary care centre were selected using convenience sampling. The incidence of VAP was estimated to be 30%. The risk factors identified for the development of VAP was found to be combined head and cervical spine injury (P=0.001), associated injuries (P=0.035), additional surgeries (P=0.025), nasogastric feeding (P=0.001), intake of immuno suppressive drugs (P=0.004), pre operative antibiotics (p=0.000) and duration of mechanical ventilation >5 days (P=0.000). The mortality among patients with VAP was found to be higher than patients without VAP (88.9% than non VAP patients).

scholarly journals A Comparative Study of CURB-65 and Expanded CURB-65 Scoring Systems in Community Acquired Pneumonia in a Tertiary Care Centre of Patna

2021 ◽  
Vol 8 (16) ◽  
pp. 1074-1078
Author(s):  
Debjit Mitra ◽  
Uttiya Roy ◽  
Abhay Kumar Sinha ◽  
Shiv Shankar Bharti
Keyword(s):  
Mechanical Ventilation ◽  
Mortality Rate ◽  
Scoring System ◽  
Tertiary Care ◽  
Community Acquired Pneumonia ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Co Morbidity ◽  
Significant Difference

BACKGROUND A variety of organisms cause community-acquired pneumonia, including bacteria, viruses and fungi. Pathogens vary in age and other factors, but the relative importance of each pneumonia as a cause of community-acquired pneumonia remains uncertain because most patients do not undergo thorough testing and because even when tested, specific agents are found in < 50 percent of cases. This study was conducted to evaluate a severity scoring system for community acquired pneumonia and compare it with the standard confusion, urea, respiratory rate, blood pressure and 65 years of age or older (CURB-65) scoring system in a tertiary care centre in Patna Medical College. METHODS This hospital based prospective study was conducted among 100 consecutive patients of community-acquired pneumonia (CAP) attending OPD or getting admitted in General Medicine ward of Patna Medical College. The CURB-65 and Expanded CURB-65 scores for these patients were calculated and the accuracy of either in predicting outcomes was statistically analysed, during the period September 2018 - May 2019. RESULTS The mean age of CAP patients in our study was 59.09 ± 12.942 years, the most common co-morbidity observed was diabetes mellitus followed by chronic obstructive pulmonary disorders (COPD), cardiovascular disease, chronic liver disease and chronic renal disease. Our study showed that the mortality rate of the study population was 12 % and 30 % patients needed admission in the ICU and 24 % patients needed invasive mechanical ventilation. In the above analysis for 30-day mortality rate, ICU admission rate, and the need for mechanical ventilation among 0 - 2 and 3 - 5 CURB 65 scores, we found no statistically significant difference (P-value = > 0.05). CONCLUSIONS The extended CURB-65 score gives priority to both clinical and laboratory parameters and is a more accurate marker for the evaluation of CAP severity and may boost the effectiveness of predicting mortality in CAP patients compared to the current CURB-65 score system. KEYWORDS CAP, CURB-65, Expanded CURB-65

Outcome of mechanical ventilation in patients of Guillain-Barre syndrome: An audit from a tertiary care centre

2013 ◽  
Vol 16 (2) ◽  
pp. 48 ◽  
Author(s):  
Afzal Azim ◽  
AK Baronia ◽  
Sanjay Singhal ◽  
M Gurjar ◽  
B Poddar ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Tertiary Care ◽  
Guillain Barre Syndrome ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Abstract #1100: Tumor Induced Osteomalacia: Clinical; Biochemical and Radiological Features from a Single Tertiary Care Centre with Emphasis on Functional Imaging.

2017 ◽  
Vol 23 ◽  
pp. 289
Author(s):  
Vineet Surana ◽  
Rajesh Khadgawat ◽  
Nikhil Tandon ◽  
Chandrashekhar Bal ◽  
Kandasamy Devasenathipathy
Keyword(s):  
Functional Imaging ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Radiological Features

Emerging Antimicrobial Resistance Among Methicillin Resistant Staphylococcus Aureus (MRSA) in a Tertiary Care Centre in North India

JMS SKIMS ◽  
2020 ◽  
Vol 23 (1) ◽  
pp. 48-49
Author(s):  
Javaid Ahmad Bhat ◽  
Shariq Rashid Masoodi
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Resistance ◽  
Tertiary Care ◽  
Resistance Mechanisms ◽  
North India ◽  
Global Public Health ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Effective Prevention ◽  
Mupirocin Resistance

Apropos to the article by Dr Bali, titled “Mupirocin resistance in clinical isolates of methicillin-sensitive and resistant Staphylococcus aureus in a tertiary care centre of North India” (1), the authors have raised important issue of emerging antimicrobial resistance (AMR). Antimicrobial resistance is an increasingly serious threat to global public health that requires action across all government sectors and society. As per WHO, AMR lurks the effective prevention and management of an ever-increasing spectrum of infections caused by bacteria, parasites, fungi and viruses. Novel resistance mechanisms are emerging and spreading globally, threatening the man’s ability to treat common infectious diseases.

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