scholarly journals Chemotherapy-induced peripheral neuropathy and its impact on health-related quality of life among multiple myeloma patients: A single-center experience

2020 ◽  
Vol 26 (4) ◽  
pp. 506
Author(s):  
NailaA Shaheen ◽  
Maha Alqahtani ◽  
NadaS Alawbthani ◽  
Abin Thomas ◽  
Ahmed Alaskar
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Peripheral Neuropathy ◽  
Health Related Quality ◽  
Single Center ◽  
Single Center Experience ◽  
Related Quality ◽  
Health Related

Extracorporeal Life Support as a Bridge to Lung Transplantation: A Single-Center Experience With an Emphasis on Health-Related Quality of Life

2017 ◽  
Vol 62 (5) ◽  
pp. 588-594 ◽  
Author(s):  
Annemieke Oude Lansink-Hartgring ◽  
Wim van der Bij ◽  
Erik A Verschuuren ◽  
Michiel E Erasmus ◽  
Adrianus J de Vries ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Transplantation ◽  
Life Support ◽  
Extracorporeal Life Support ◽  
Health Related Quality ◽  
Single Center ◽  
Single Center Experience ◽  
Related Quality ◽  
Health Related

Long-term health-related quality of life of living kidney donors: a single-center experience

2015 ◽  
Vol 24 (12) ◽  
pp. 2833-2842 ◽  
Author(s):  
Christian Benzing ◽  
Hans-Michael Hau ◽  
Greta Kurtz ◽  
Moritz Schmelzle ◽  
Hans-Michael Tautenhahn ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Single Center ◽  
Kidney Donors ◽  
Living Kidney Donors ◽  
Single Center Experience ◽  
Related Quality ◽  
Health Related

scholarly journals Exploring the relationship among dispositional optimism, health-related quality of life, and CIPN severity among colorectal cancer patients with chronic peripheral neuropathy

2021 ◽  
Author(s):  
Hester.R. Trompetter ◽  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Gerard Vreugdenhil ◽  
Floortje Mols
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Peripheral Neuropathy ◽  
Cancer Patients ◽  
Anxiety Symptoms ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Purpose Chemotherapy-induced peripheral neuropathy ((CI)PN) becomes chronic in 30% of cancer patients. Knowledge of predictors of chronic (CI)PN and related impairments in health-related quality of life (HRQoL) is lacking. We examined the role of optimism in chronic (CI)PN severity and associated HRQoL in colorectal cancer (CRC) patients up to two years after diagnosis. Methods CRC patients from a prospective cohort study participated, with sensory peripheral neuropathy (SPN) 1 year after diagnosis (n = 142). Multivariable regression analyses examined the cross-sectional association between optimism (measured by the LOT-R) and SPN severity/HRQoL (measured by the EORTC QLQ-CIPN20 and QLQ-C30), as well as the prospective association in a subsample that completed measures 2 years after diagnosis and still experienced SPN (n = 86). Results At 1-year follow-up, higher optimism was associated with better global HRQoL, and better physical, role, emotional, cognitive, and social functioning (all p < .01). Optimism at year one was also prospectively associated with better global HRQoL (p < .05), and emotional and cognitive functioning at 2-year follow-up (both p < .01). Optimism was not related to self-reported SPN severity. Significant associations were retained when controlling for demographic/clinical variables, and became non-significant after controlling for depressive and anxiety symptoms. Conclusions Optimism and depressive and anxiety symptoms are associated with HRQoL in CRC patients with chronic (CI)PN. Future research may illuminate the mechanisms that these factors share, like the use of (non)adaptive coping styles such as avoidance and acceptance that may inform the design of targeted interventions to help patients to adapt to chronic (CI)PN.

scholarly journals The course of peripheral neuropathy and its association with health-related quality of life among colorectal cancer patients

2020 ◽  
Author(s):  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Dareczka K. Wasowicz ◽  
Laurens V. Beerepoot ◽  
Gerard Vreugdenhil ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Peripheral Neuropathy ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
The Impact

Abstract Purpose To gain more insight into the course of chemotherapy-induced peripheral neuropathy (CIPN) and its impact on health-related quality of life (HRQoL) in a population-based sample of colorectal cancer (CRC) patients up to 2 years after diagnosis. Methods All newly diagnosed CRC patients from four hospitals in the Netherlands were eligible for participation in an ongoing prospective cohort study. Patients (n = 340) completed questions on CIPN (EORTC QLQ-CIPN20) and HRQoL (EORTC QLQ-C30) before initial treatment (baseline) and 1 and 2 years after diagnosis. Results Among chemotherapy-treated patients (n = 105), a high sensory peripheral neuropathy (SPN) level was reported by 57% of patients at 1 year, and 47% at 2-year follow-up, whereas a high motor peripheral neuropathy (MPN) level was reported by 47% and 28%, at years 1 and 2, respectively. Linear mixed model analyses showed that SPN and MPN symptoms significantly increased from baseline to 1-year follow-up and did not return to baseline level after 2 years. Patients with a high SPN or MPN level reported a worse global quality of life and a worse physical, role, emotional, cognitive, and social functioning compared with those with a low SPN or MPN level. Conclusions Future studies should focus on understanding the mechanisms underlying CIPN so targeted interventions can be developed to reduce the impact of CIPN on patient’s lives. Implications for cancer survivors Patients need to be informed of both CIPN and the impact on HRQoL.

Measurement of health‐related quality of life in multiple myeloma

1996 ◽  
Vol 92 (3) ◽  
pp. 604-613 ◽  
Author(s):  
Finn Wisløff ◽  
Sverre Eika ◽  
Erik Hippe ◽  
Martin Hjorth ◽  
Erik Holmberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related
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