The value of arterial blood gas parameters for prediction of mortality in survivors of Out-of-hospital cardiac arrest

AbstractWe aimed to investigate the prognostic value of dynamic changes in arterial blood gas analysis (ABGA) measured after the start of cardiopulmonary resuscitation (CPR) for return of spontaneous circulation (ROSC) in patients with out-of-hospital cardiac arrest (OHCA). This prospective observational study was conducted at the emergency department of a university hospital from February 2018 to February 2020. All blood samples for gas analysis were collected from a radial or femoral arterial line, which was inserted during CPR. Changes in ABGA parameters were expressed as delta (Δ), defined as the values of the second ABGA minus the values of the initial ABGA. The primary outcome was sustained ROSC. Out of the 80 patients included in the analysis, 13 achieved sustained ROSC after in-hospital resuscitation. Multivariable logistic analysis revealed that ΔpaO2 (odds ratio [OR] = 1.023; 95% confidence interval [CI] = 1.004–1.043, p = 0.020) along with prehospital shockable rhythm (OR = 84.680; 95% CI = 2.561–2799.939, p = 0.013) and total resuscitation duration (OR = 0.881; 95% CI = 0.805–0.964, p = 0.006) were significant predictors for sustained ROSC. Our study suggests a possible association between ΔpaO2 in ABGA during CPR and an increased rate of sustained ROSC in the late phase of OHCA.

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Arterial Blood Gas Tensions After Resuscitation From Out-of-Hospital Cardiac Arrest

Critical Care Medicine ◽

10.1097/ccm.0000000000000228 ◽

2014 ◽

Vol 42 (6) ◽

pp. 1463-1470 ◽

Cited By ~ 102

Author(s):

Jukka Vaahersalo ◽

Stepani Bendel ◽

Matti Reinikainen ◽

Jouni Kurola ◽

Marjaana Tiainen ◽

...

Keyword(s):

Cardiac Arrest ◽

Blood Gas ◽

Arterial Blood Gas ◽

Arterial Blood ◽

Hospital Cardiac Arrest

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The utility of arterial blood gas parameters and chest radiography in predicting appropriate intubations in burn patients with suspected inhalation injury- a retrospective cohort study

Burns ◽

10.1016/j.burns.2021.02.018 ◽

2021 ◽

Author(s):

Minesh Chotalia ◽

Christine Pirrone ◽

Muzzammil Ali ◽

Randeep Mullhi ◽

Barbara Torlinska ◽

...

Keyword(s):

Cohort Study ◽

Retrospective Cohort Study ◽

Chest Radiography ◽

Retrospective Cohort ◽

Inhalation Injury ◽

Burn Patients ◽

Blood Gas ◽

Arterial Blood Gas ◽

Arterial Blood ◽

Blood Gas Parameters

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Sedative and cardiopulmonary effects of acepromazine, midazolam, butorphanol, acepromazine-butorphanol and midazolam-butorphanol on propofol anaesthesia in goats

Journal of the South African Veterinary Association ◽

10.4102/jsava.v80i1.162 ◽

2009 ◽

Vol 80 (1) ◽

Author(s):

T.B. Dzikitia ◽

G.F. Stegmanna ◽

L.J. Hellebrekers ◽

R.E.J. Auer ◽

L.N. Dzikiti

Keyword(s):

Saline Group ◽

Control Group ◽

Blood Gas ◽

Arterial Blood Gas ◽

Induction Dose ◽

Normal Limits ◽

Arterial Blood ◽

Blood Gas Parameters ◽

Induction Of Anaesthesia

The sedative, propofol-sparing and cardiopulmonary effects of acepromazine, midazolam, butorphanol and combinations of butorphanol with acepromazine or midazolam in goats were evaluated. Six healthy Boer - Indigenous African crossbreed goats were by randomised cross-over designated to 6 groups: Group SAL that received saline, Group ACE that received acepromazine, Group MID that received midazolam, Group BUT that received butorphanol, Group ACEBUT that received acepromazine and butorphanol and Group MIDBUT that received midazolam and butorphanol as premedication agents intramuscularly on different occasions at least 3 weeks apart. The degree of sedation was assessed 20 minutes after administration of the premedication agents. Thirty minutes after premedication, the dose of propofol required for induction of anaesthesia adequate to allow placement of an endotracheal tube was determined. Cardiovascular, respiratory and arterial blood-gas parameters were assessed up to 30 minutes after induction of general anaesthesia. Acepromazine and midazolam produced significant sedation when administered alone, but premedication regimens incorporating butorphanol produced inconsistent results. The dose of propofol required for induction of anaesthesia was significantly reduced in goats that received midazolam alone, or midazolam combined with either acepromazine or butorphanol. The quality of induction of anaesthesia was good in all groups, including the control group. Cardiovascular, respiratory and blood-gas parameters were within normal limits in all groups and not significantly different between or within all groups. In conclusion: sedation with midazolam alone, or midazolam combined with either acepromazine or butorphanol significantly reduces the induction dose of propofol with minimal cardiopulmonary effects in goats.

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An update report on the harmonization of adult reference intervals in Australasia

Clinical Chemistry and Laboratory Medicine (CCLM) ◽

10.1515/cclm-2017-0920 ◽

2018 ◽

Vol 0 (0) ◽

Cited By ~ 1

Author(s):

Gus Koerbin ◽

Ken Sikaris ◽

Graham R.D. Jones ◽

Robert Flatman ◽

Jillian R. Tate

Keyword(s):

Royal College ◽

Clinical Chemistry ◽

Metrological Traceability ◽

Reference Intervals ◽

Evidence Based ◽

Blood Gas ◽

Arterial Blood Gas ◽

The Past ◽

Arterial Blood ◽

Blood Gas Parameters

Abstract The Australasian Association of Clinical Biochemists (AACB) has over the past 5 years been actively working to achieve harmonized reference intervals (RIs) for common clinical chemistry analytes using an evidence-based checklist approach where there is sound calibration and metrological traceability. It has now recommended harmonized RIs for 18 common clinical chemistry analytes which are performed in most routine laboratories and these have been endorsed by the Royal College of Pathologists of Australasia (RCPA). In 2017 another group of analytes including urea, albumin and arterial blood gas parameters were considered and suggested harmonized RIs proposed. This report provides an update of those harmonization efforts.

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The effects of lung volume reduction treatment on diffusing capacity and gas exchange

European Respiratory Review ◽

10.1183/16000617.0171-2019 ◽

2020 ◽

Vol 29 (158) ◽

pp. 190171

Author(s):

Marlies van Dijk ◽

Karin Klooster ◽

Nick H.T. Ten Hacken ◽

Frank Sciurba ◽

Huib. A.M. Kerstjens ◽

...

Keyword(s):

Gas Exchange ◽

Lung Volume ◽

Diagnostic Techniques ◽

Volume Reduction ◽

Diffusing Capacity ◽

Blood Gas ◽

Lung Volume Reduction ◽

Arterial Blood Gas ◽

Arterial Blood ◽

Blood Gas Parameters

Lung volume reduction (LVR) treatment in patients with severe emphysema has been shown to have a positive effect on hyperinflation, expiratory flow, exercise capacity and quality of life. However, the effects on diffusing capacity of the lungs and gas exchange are less clear. In this review, the possible mechanisms by which LVR treatment can affect diffusing capacity of the lung for carbon monoxide (DLCO) and arterial gas parameters are discussed, the use of DLCO in LVR treatment is evaluated and other diagnostic techniques reflecting diffusing capacity and regional ventilation (V′)/perfusion (Q′) mismatch are considered.A systematic review of the literature was performed for studies reporting on DLCO and arterial blood gas parameters before and after LVR surgery or endoscopic LVR with endobronchial valves (EBV). DLCO after these LVR treatments improved (40 studies, n=1855) and the mean absolute change from baseline in % predicted DLCO was +5.7% (range −4.6% to +29%), with no real change in blood gas parameters. Improvement in V′ inhomogeneity and V′/Q′ mismatch are plausible explanations for the improvement in DLCO after LVR treatment.

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