scholarly journals Intravenous ketamine for pain relief in a patient with supraglottic laryngeal cancer (Stage IV-C)

2020 ◽  
Vol 6 (2) ◽  
pp. 8
Author(s):  
Sagar Karia ◽  
Prashant Chaudhari ◽  
Bhumika Shah ◽  
Nilesh Shah ◽  
AvinashDe Sousa
Keyword(s):  
Pain Relief ◽  
Laryngeal Cancer ◽  
Stage Iv ◽  
Cancer Stage ◽  
Intravenous Ketamine

scholarly journals Intra- and Postoperative Very Low Dose Intravenous Ketamine Infusion Does Not Increase Pain Relief after Major Spine Surgery in Patients with Preoperative Narcotic Analgesic Intake

Pain Medicine ◽  
2011 ◽  
Vol 12 (8) ◽  
pp. 1276-1283 ◽  
Author(s):  
Kathirvel Subramaniam ◽  
Vimal Akhouri ◽  
Paul A. Glazer ◽  
Jacob Rachlin ◽  
Lisa Kunze ◽  
...  
Keyword(s):  
Pain Relief ◽  
Spine Surgery ◽  
Low Dose ◽  
Narcotic Analgesic ◽  
Ketamine Infusion ◽  
Intravenous Ketamine

17 Assessment of therapy by the serum markers - TPS and CA15-3 - related to the UICC criteria in breast cancer Stage IV

The Breast ◽  
1995 ◽  
Vol 4 (1) ◽  
pp. 69
Author(s):  
P.-E. Jonsson ◽  
M. Malmberg ◽  
G. Nordin
Keyword(s):  
Breast Cancer ◽  
Stage Iv ◽  
Serum Markers ◽  
Cancer Stage

scholarly journals The Causes of Deaths Occurred in Patients of Early Stage Laryngeal Cancer (Stage I, Stage II)

2005 ◽  
Vol 17 (1) ◽  
pp. 11-16
Author(s):  
Mioko Matsuo ◽  
Fumihide Rikimaru ◽  
Satoshi Tou ◽  
Yuuichirou Higaki ◽  
Kichinobu Tomita
Keyword(s):  
Laryngeal Cancer ◽  
Early Stage ◽  
Stage I ◽  
Stage Ii ◽  
Cancer Stage ◽  
Causes Of Deaths

Breast Cancer Stage Is Associated With Exceeding Target Price in the Oncology Care Model

2021 ◽  
Author(s):  
Ryan B. Thomas ◽  
Vittorio Maio ◽  
Anna Chen ◽  
Seojin Park ◽  
Dexter Waters ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Academic Medical Center ◽  
Stage Iv ◽  
Cost Of Care ◽  
Mean Difference ◽  
Cancer Stage ◽  
Care Model ◽  
Target Price ◽  
Old Patients ◽  
Oncology Care

PURPOSE: To explore mean difference between Oncology Care Model (OCM) total costs and target price among breast cancer episodes by stage under the Centers for Medicare and Medicaid Services OCM payment methodology. METHODS: Breast cancer episodes from OCM performance period 1-4 reconciliation reports (July 1, 2016-July 1, 2018) were linked with health record data from a large, academic medical center. Demographics, total cost of care (TCOC), and target price were measured by stage. Adjusted differences between TCOC and target price were compared across cancer stage using multivariable linear regression. RESULTS: A total of 539 episodes were evaluated from 252 unique patients with breast cancer, of which 235 (44%) were stage I, 124 (23%) stage II, 33 (6%) stage III, and 147 (27%) stage IV. About 37% of episodes exceeded target price. Mean differences from target price were –$1,782, $2,246, –$6,032, and $11,379 all in US dollars (USD) for stages I through IV, respectively. Stage IV episodes had highest mean TCOC ($44,210 USD) and mean target price ($32,831 USD) but also had higher rates of chemotherapy, inpatient admission, and novel therapy use. After adjusting for covariates, stage IV and ≥ 65-year-old patients had the highest mean difference from target price ($17,175 USD; 95% CI, $12,452 to $21,898 USD). CONCLUSION: Breast cancer episodes in older women with distant metastases most frequently exceeded target price, suggesting that target price did not adequately account for complexity of metastatic cancers. A metastatic adjustment introduced in PP7 represents a promising advancement in the target price methodology and an impact evaluation will be needed.

Intravenous ketamine as an analgesia in prehospital adult trauma patients

2022 ◽  
Vol 14 (1) ◽  
pp. 26-36
Author(s):  
Anya Critchley
Keyword(s):  
Pain Relief ◽  
Major Trauma ◽  
Trauma Patients ◽  
First Line ◽  
Exclusion Criteria ◽  
Adequate Pain Relief ◽  
Research Questions ◽  
Effective Pain Relief ◽  
Intravenous Ketamine

Background: Prehospital traumatic pain is common, but the quality of pain management in these patients is poor. Current practice recommends morphine as the first-line analgesia in major trauma but this carries high risks and is often contraindicated. Alternative paramedic-administered analgesia does not provide adequate pain relief or may be contraindicated. As a result, many patients remain in pain. Analgesic ketamine is used safely and effectively in international civilian and military settings and by paramedics with additional training, education and qualifications. Aim: The study had two aims. Namely, these were to find out whether intravenous ketamine: provides effective relief of prehospital traumatic pain in adults; and is safe for prehospital administration by non-specialist paramedics. Method: Three databases, CINAHL, MEDLINE and AMED, were searched to identify articles published between 2009 and 2021. Exclusion criteria were applied and results subjected to critical appraisal and evaluation. Findings: Four studies were included in the review. Two themes were identified for thematic analysis: therapeutic effectiveness; and the safety of IV ketamine administration by paramedics. The evidence drew predominantly homogenous conclusions, but was substandard regarding external validity, which limited the quality of these conclusions. Conclusion: Ketamine provides effective pain relief in line with morphine and is safe for paramedics to administer. However, clear gaps in the evidence mean the research questions are not fully answered, so changes to current paramedic practice cannot be recommended.

scholarly journals Colorectal Signet Ring Cell Carcinoma in a Young Pregnant Woman

2020 ◽  
Vol 13 (1) ◽  
pp. 182-187
Author(s):  
Francisco Ibargüengoitia Ochoa ◽  
Gerardo Miranda Dévora ◽  
Leonardo Silva Lino ◽  
Cintia Sepulveda Rivera ◽  
Diego González Vázquez ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Carcinoma ◽  
Stage Iv ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
High Morbidity ◽  
Cancer Stage ◽  
Signet Ring ◽  
Histologic Differentiation ◽  
Ring Cell

Colorectal cancer during pregnancy is one of the less common neoplasms with an incidence of 0.8 in 100,000 pregnancies. Primary colonic signet ring cell carcinoma is a weird variety, characterized by a poor histologic differentiation, with a high morbidity-mortality rate. The case of a 24-year-old patient with a 22-week-old pregnancy and colorectal cancer stage IV in palliative state is presented, with a devastating result. Early diagnosis represents a challenge because of the presentation form and the histologic aggressiveness of this disease. We suggest that colorectal cancer during pregnancy must be treated by a multidisciplinary team.

Transsphenoidal hypophysectomy for disseminated carcinoma of the prostate gland

1979 ◽  
Vol 50 (3) ◽  
pp. 275-282 ◽  
Author(s):  
George T. Tindall ◽  
Nettleton S. Payne ◽  
Daniel W. Nixon
Keyword(s):  
Pain Relief ◽  
Operative Procedure ◽  
Prostate Gland ◽  
Stage Iv ◽  
Early Postoperative Period ◽  
Significant Feature ◽  
Content Type ◽  
Carcinoma Of The Prostate ◽  
Microsurgical Approach ◽  
Fine Print

✓ Transsphenoidal microsurgical hypophysectomy was performed in 53 men with disseminated carcinoma (Stage IV) of the prostate gland. The mean age was 64.8 years. Forty-three of the 53 men had severe pain due to their disease. Significant pain relief was obtained following hypophysectomy, usually within 24 hours, in 39 (91%) of these 43 patients. Objective remission occurred in 16 (36%) of 45 patients in whom the follow-up review was adequate to make this decision. Although dramatic, pain relief was not permanent in every patient. Four patients died in the early postoperative period, and in one, death was directly related to the operative procedure. Significant complications included partial diabetes insipidus in 40 cases (75.5%), and cerebrospinal fluid leaks in six (11.3%). The authors conclude that hypophysectomy is an appropriate operation in patients with disseminated carcinoma of the prostate gland, particularly when pain is a significant feature of the illness. Further, the transsphenoidal microsurgical approach appears to be the operative procedure of choice for performing hypophysectomy.

Role of surgical resection among chemotherapy-treated patients with colorectal cancer stage IV disease: A survival analysis.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 3564-3564 ◽  
Author(s):  
B. S. Lin ◽  
A. Ziogas ◽  
T. E. Seery ◽  
M. J. Stamos ◽  
J. A. Zell
Keyword(s):  
Colorectal Cancer ◽  
Survival Analysis ◽  
Surgical Resection ◽  
Stage Iv ◽  
Cancer Stage ◽  
Stage Iv Disease

Relationships among patients’ ability to identify their cancer stage, knowledge of care options, and management of transitions.

2014 ◽  
Vol 32 (31_suppl) ◽  
pp. 224-224
Author(s):  
Jenna Hinchey ◽  
Jessica Goldberg ◽  
Sarah Linsky ◽  
Rebecca Linsky ◽  
Sangchoon Jeon ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Depression Scale ◽  
Metastatic Breast ◽  
Stage Iv ◽  
Stage I ◽  
Self Management ◽  
Future Research ◽  
Cancer Stage ◽  
Younger Age ◽  
Stage Iv Breast Cancer

224 Background: Discrepancies may exist between what oncologists communicate and what patients understand about their cancer stage. We explored women’s ability to correctly identify their stage of breast cancer among a sample of women recently diagnosed with nonmetastatic (Stage I-III) disease. Methods: As part of a cancer self-management study, we asked women with non-metastatic breast cancer to identify their stage of disease. Participants’ responses were compared to their electronic medical record (EMR) for validation. We calculated descriptive statistics and used logistic regression to examine relationships between knowledge of stage, demographic and clinical variables, and study outcomes (Control Preferences Scale- CPS, Knowledge of Care Options Test- KOCO, Measurement of Transitions Scale- MOT, Medical Communication Competence Scale- MCCS, Chronic Disease Self-Efficacy Scale- CDSE, Uncertainty in Illness Scale- MUIS-C, and Hospital Anxiety and Depression Scale- HADS). Results: Participants (n= 100) had a mean age of 52.3 years (range 27-72). Per the EMR, 19 participants (19%) had Stage I breast cancer, 57 (57%) had Stage II, and 24 (24%) had Stage III. Twenty-nine participants (29%) were unable to correctly identify their stage of cancer. Of this group, 11 (39.3%) provided vague responses, 11 (39.3%) reported an incorrect stage, and 7 (25%) did not know/want to know their stage. Younger age (p=.0412) and earlier cancer stage (p=.0136) were predictive of correctly identifying cancer stage. Participants who at baseline had a greater knowledge of care options were more likely to correctly identify their cancer stage (KOCO, p=.0482). Those who correctly identified their cancer stage were better able to manage transitions over time (MOT, p=.0564) than those unable to identify their stage. Conclusions: Women who cannot correctly identify their cancer stage may neither understand its implications nor effectively participate in cancer self-management. Conversations about cancer stage should be revisited to ensure patients’ understanding. Future research should include women with Stage IV breast cancer to more completely investigate ability to identify cancer stage.

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