Emancipation of our medical researchers: Long overdue

Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; especially when used along with targeting and triggering techniques. This work traces back the history of chemotherapy, addressing the main challenges that have encouraged the medical researchers to seek a sanctuary in nanotechnological-based drug delivery systems that are grafted with appropriate targeting techniques and drug release mechanisms. A special focus will be directed to acoustically triggered liposomes encapsulating doxorubicin.

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Using increased trust in medical researchers to increase minority recruitment: The RECRUIT cluster randomized clinical trial

Contemporary Clinical Trials ◽

10.1016/j.cct.2021.106519 ◽

2021 ◽

pp. 106519

Author(s):

Barbara C. Tilley ◽

Arch G. Mainous ◽

Rossybelle P. Amorrortu ◽

M. Diane McKee ◽

Daniel W. Smith ◽

...

Keyword(s):

Clinical Trial ◽

Randomized Clinical Trial ◽

Minority Recruitment ◽

Medical Researchers ◽

Cluster Randomized

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Scientists in pyjamas: characterising the working arrangements and productivity of Australian medical researchers during the COVID‐19 pandemic

The Medical Journal of Australia ◽

10.5694/mja2.50860 ◽

2020 ◽

Vol 213 (11) ◽

pp. 516-520 ◽

Cited By ~ 1

Author(s):

David G Chapman ◽

Cindy Thamrin

Keyword(s):

Medical Researchers

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TREASURE: Text Mining Algorithm Based On Affinity Analysis and Set Intersection to Find the Action of Tuberculosis Drugs against Other Pathogens

Applied Sciences ◽

10.3390/app11156834 ◽

2021 ◽

Vol 11 (15) ◽

pp. 6834

Author(s):

Pradeepa Sampath ◽

Nithya Shree Sridhar ◽

Vimal Shanmuganathan ◽

Yangsun Lee

Keyword(s):

Text Mining ◽

Causes Of Death ◽

Intersection Property ◽

Research Papers ◽

Bacterial Diseases ◽

Mining Algorithm ◽

Set Intersection ◽

The World ◽

Medical Researchers

Tuberculosis (TB) is one of the top causes of death in the world. Though TB is known as the world’s most infectious killer, it can be treated with a combination of TB drugs. Some of these drugs can be active against other infective agents, in addition to TB. We propose a framework called TREASURE (Text mining algoRithm basEd on Affinity analysis and Set intersection to find the action of tUberculosis dRugs against other pathogEns), which particularly focuses on the extraction of various drug–pathogen relationships in eight different TB drugs, namely pyrazinamide, moxifloxacin, ethambutol, isoniazid, rifampicin, linezolid, streptomycin and amikacin. More than 1500 research papers from PubMed are collected for each drug. The data collected for this purpose are first preprocessed, and various relation records are generated for each drug using affinity analysis. These records are then filtered based on the maximum co-occurrence value and set intersection property to obtain the required inferences. The inferences produced by this framework can help the medical researchers in finding cures for other bacterial diseases. Additionally, the analysis presented in this model can be utilized by the medical experts in their disease and drug experiments.

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Publishing at any cost: a cross-sectional study of the amount that medical researchers spend on open access publishing each year

BMJ Open ◽

10.1136/bmjopen-2020-047107 ◽

2021 ◽

Vol 11 (2) ◽

pp. e047107

Author(s):

Mallory K. Ellingson ◽

Xiaoting Shi ◽

Joshua J. Skydel ◽

Kate Nyhan ◽

Richard Lehman ◽

...

Keyword(s):

Open Access ◽

Senior Author ◽

High Impact ◽

Open Access Publishing ◽

Original Research ◽

Potential Cost ◽

Cross Sectional ◽

Review Articles ◽

Open Access Journals ◽

Medical Researchers

ObjectiveTo estimate the financial costs paid by individual medical researchers from meeting the article processing charges (APCs) levied by open access journals in 2019.DesignCross-sectional analysis.Data sourcesScopus was used to generate two random samples of researchers, the first with a senior author article indexed in the ‘Medicine’ subject area (general researchers) and the second with an article published in the ten highest-impact factor general clinical medicine journals (high-impact researchers) in 2019. For each researcher, Scopus was used to identify all first and senior author original research or review articles published in 2019. Data were obtained from Scopus, institutional profiles, Journal Citation Reports, publisher databases, the Directory of Open Access Journals, and individual journal websites.Main outcome measuresMedian APCs paid by general and high-impact researchers for all first and senior author research and review articles published in 2019.ResultsThere were 241 general and 246 high-impact researchers identified as eligible for our study. In 2019, the general and high-impact researchers published a total of 914 (median 2, IQR 1–5) and 1471 (4, 2–8) first or senior author research or review articles, respectively. 42% (384/914) of the articles from the general researchers and 29% (428/1471) of the articles from the high-impact medical researchers were published in fully open access journals. The median total APCs paid by general researchers in 2019 was US$191 (US$0–US$2500) and the median total paid by high-impact researchers was US$2900 (US$0–US$5465); the maximum paid by a single researcher in total APCs was US$30115 and US$34676, respectively.ConclusionsMedical researchers in 2019 were found to have paid between US$0 and US$34676 in total APCs. As journals with APCs become more common, it is important to continue to evaluate the potential cost to researchers, especially on individuals who may not have the funding or institutional resources to cover these costs.

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JADE: A tool for medical researchers to explore adverse drug events using health claims data

Applied Clinical Informatics ◽

10.4338/aci-2014-04-ra-0036 ◽

2014 ◽

Vol 05 (03) ◽

pp. 621-629 ◽

Cited By ~ 4

Author(s):

S.K. Sauter ◽

C. Rinner ◽

L.M. Neuhofer ◽

M. Wolzt ◽

W. Grossmann ◽

...

Keyword(s):

Adverse Drug Events ◽

Claims Data ◽

Age Groups ◽

Rule Learning ◽

Health Claims ◽

Drug Event ◽

Study Cohort ◽

Defined Daily Doses ◽

Health Claims Data ◽

Medical Researchers

SummaryObjective: The objective of our project was to create a tool for physicians to explore health claims data with regard to adverse drug reactions. The Java Adverse Drug Event (JADE) tool should enable the analysis of prescribed drugs in connection with diagnoses from hospital stays.Methods: We calculated the number of days drugs were taken by using the defined daily doses and estimated possible interactions between dispensed drugs using the Austria Codex, a database including drug-drug interactions. The JADE tool was implemented using Java, R and a PostgreSQL database.Results: Beside an overview of the study cohort which includes selection of gender and age groups, selected statistical methods like association rule learning, logistic regression model and the number needed to harm have been implemented.Conclusion: The JADE tool can support physicians during their planning of clinical trials by showing the occurrences of adverse drug events with population based information.Citation: Edlinger D, Sauter SK, Rinner C, Neuhofer LM, Wolzt M, Grossmann W, Endel G, Gall W. JADE: A tool for medical researchers to explore adverse drug events using health claims data. Appl Clin Inf 2014; 5: 621–629http://dx.doi.org/10.4338/ACI-2014-04-RA-0036

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Medical researchers set up UK body to raise public profile

Nature ◽

10.1038/35941 ◽

1998 ◽

Vol 391 (6670) ◽

pp. 827-827

Author(s):

Asako Saegusa

Keyword(s):

Medical Researchers ◽

Set Up

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Journal selection behavior among early-career academicians in Iran: how they choose the most appropriate journal for their publications

Global Knowledge Memory and Communication ◽

10.1108/gkmc-09-2021-0146 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Amrollah Shamsi ◽

Brady D_ Lund ◽

Shohreh SeyyedHosseini ◽

Reza BasirianJahromi

Keyword(s):

Early Career ◽

Medical Sciences ◽

Online Questionnaire ◽

Scholarly Journals ◽

Content Type ◽

Academic Promotion ◽

Promotion Policies ◽

Medical Researchers ◽

Selection Behavior ◽

The Right

Purpose Journals are the essential tools of researchers, especially academicians, to present their scientific findings. So, choosing the right journal helps not only science development but also their academic promotion. The purpose of this study is to examine the factors that Iranian medical researchers consider when selecting scholarly journals in which to submit their work. Design/methodology/approach A self-administered online questionnaire was emailed in May 2021, with 101 responses received. The sample included all the faculty members with the role of “lecturer” in Iranian medical universities and who have 1–5 articles in the Scopus database as early-career Iranian medical researchers. The questionnaire consisted of 36 items, divided into five sections: basic information, attitudes and beliefs, ways to choose a journal, problems and familiarity with the components of scientometrics/validity metrics related to journals. Findings The findings indicate that these researchers value the expertise of experienced researchers and professionals, like librarians, when selecting publication venues. They often use journal indexes to guide journal selection. They also consider factors like the length of typical peer review and the complexity of submission guidelines when making decisions. Research limitations/implications The study of one country, though detecting requirements of journal selection behavior, cannot be generalized to the entire region. Practical implications The current study has academic implications as far as decisions on journal selection are concerned. University policymakers in Iran may consider re-examining their emphasis on academicians’ promotion policies at Iranian universities of medical sciences. Originality/value These findings may support the work of early-career researchers and those individuals (e.g., librarians) that serve them, as well as publishers and editors of scholarly journals.

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