Malignant squamous cell carcinoma arising in a previously resected cerebellopontine angle epidermoid

Intracranial epidermoid cysts represent a group of relatively common, benign, indolent tumors most frequently encountered at the cerebellopontine angle. Presentation is usually secondary to compressive neurologic symptoms. Treatment is surgical debulking and generally is curative. As with other epidermoid cysts throughout the body, the risk of degeneration into squamous cell carcinoma is a rare complication that is typically fatal within the CNS.

Download Full-text

Squamous Cell Carcinoma Metastatic to the Cerebellopontine Angle

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949410301115 ◽

1994 ◽

Vol 103 (11) ◽

pp. 908-910 ◽

Cited By ~ 5

Author(s):

Miriam I. Redleaf ◽

John F. Laurenzo ◽

Carol A. Bauer ◽

Bruce J. Gantz

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Cerebellopontine Angle

Download Full-text

Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report

Case Reports in Neurological Medicine ◽

10.1155/2011/525289 ◽

2011 ◽

Vol 2011 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Fayçal Lakhdar ◽

El Mehdi Hakkou ◽

Rachid Gana ◽

Rachid My Maaqili ◽

Fouad Bellakhdar

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Malignant Transformation ◽

Squamous Cell ◽

Epidermoid Cyst ◽

Cerebellopontine Angle ◽

Histopathological Examination ◽

Benign Tumors ◽

Epidermoid Cysts ◽

Intracranial Epidermoid

Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.

Download Full-text

Squamous Cell Carcinoma Arising in a Remnant of an Extirpated Cerebellopontine Angle Epidermoid Tumor: Case Report and Literature Review

Journal of Neurological Surgery Part B Skull Base ◽

10.1055/s-0033-1336404 ◽

2013 ◽

Vol 74 (S 01) ◽

Author(s):

Seth Kaplan ◽

Mara Modest ◽

Christopher Farrell ◽

Gregory Artz

Keyword(s):

Squamous Cell Carcinoma ◽

Case Report ◽

Literature Review ◽

Cell Carcinoma ◽

Squamous Cell ◽

Cerebellopontine Angle ◽

Epidermoid Tumor

Download Full-text

Primary Intracranial Squamous Cell Carcinoma in the Brain Stem with a Cerebellopontine Angle Epidermoid Cyst

Journal of Korean Neurosurgical Society ◽

10.3340/jkns.2008.44.6.401 ◽

2008 ◽

Vol 44 (6) ◽

pp. 401 ◽

Cited By ~ 16

Author(s):

Min-Su Kim ◽

Oh-Lyong Kim

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Brain Stem ◽

Squamous Cell ◽

Epidermoid Cyst ◽

Cerebellopontine Angle ◽

The Brain

Download Full-text

Primary intracranial squamous cell carcinoma of the right cerebellopontine angle

Journal of Neurosurgery ◽

10.3171/jns.1981.54.6.0824 ◽

1981 ◽

Vol 54 (6) ◽

pp. 824-828 ◽

Cited By ~ 46

Author(s):

Carlos A. Garcia ◽

Paul A. McGarry ◽

Fred Rodriguez

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Cerebellopontine Angle ◽

Middle Aged ◽

Content Type ◽

The Right ◽

Fine Print

✓ A case of primary solid squamous cell carcinoma of the right cerebellopontine angle is described, and the literature is reviewed. Thirteen cases selected by strict criteria are analyzed, and the behavior of the lesion is described. This lesion seems to be found predominantly in middle-aged males in the cerebellopontine angle or parapontine region, and grows slowly.

Download Full-text