scholarly journals Application of the Steady-state Variable Nutation Angle Method for Faster Determinations of Long T1S–-an Approach Useful for the Design of Hyperpolarized Mr Molecular Probes

2015 ◽  
Vol 8s1 ◽  
pp. MRI.S29358 ◽  
Author(s):  
Marc Jupin ◽  
Ayelet Gamliel ◽  
Yonatan Hovav ◽  
Jacob Sosna ◽  
J. Moshe Gomori ◽  
...  

In the dissolution-dynamic nuclear polarization technique, molecular probes with long T1s are preferred. 13C nuclei of small molecules with no directly bonded protons or sp313C nuclei with proton positions substituted by deuterons may fulfill this requirement. The T1 determination of such new molecular probes is crucial for the success of the hyperpolarized observation. Although the inversion-recovery approach remained by and large the standard for T1 measurements, we show here that the steady-state variable nutation angle approach is faster and may be better suited for the determination of relatively long T1s in thermal equilibrium. Specifically, the T1 of a new molecular probe, [uniformly labeled (UL)-13C6, UL-2H8]2-deoxy-d-glucose, is determined here and compared to that of [UL-13C6, UL-2H7]d-glucose.

Clean Air ◽  
2007 ◽  
Vol 8 (4) ◽  
pp. 359-371
Author(s):  
A. Medeiros ◽  
R. Edenhofer ◽  
K. Lucka ◽  
H. Kohne

1989 ◽  
Vol 20 (2) ◽  
pp. 85-96 ◽  
Author(s):  
Gunnar Jacks ◽  
Göran Åberg ◽  
P. Joseph Hamilton

Strontium isotopes in precipitation, soil and runoff water can be used to establish a ratio of wet plus dry deposited Sr to Sr released by weathering. This ratio is especially enhanced in areas with old acid Proterozoic rocks (0.6-2.5 Ga) and Archean rocks (>2.5 Ga). Since Sr and Ca behave in an analogous way in the coniferous forest ecosystem the results for Sr can be used for the determination of Ca. If the deposition of calcium can be calculated reasonably accurately the weathering rate can also be estimated. Five catchments have been investigated using this approach. Three of them seem to be close to a steady state, wherein the losses and gains of calcium to the system are equal. In the two southern-most catchments there seems to be an ongoing loss of exchangeable calcium. The loss by runoff occurs with sulphate being the dominant anion. Weathering rates of 1.5 to 4.8 kg Ca/ha year have been estimated.


1996 ◽  
Vol 27 (4) ◽  
pp. 247-254 ◽  
Author(s):  
Zekâi Şen

A simple, approximate but practical graphical method is proposed for estimating the storage coefficient independently from the transmissivity value, provided that quasi-steady state flow data are available from a pumping test. In the past, quasi-steady state flow distance-drawdown data have been used for the determination of transmissivity only. The method is applicable to confined and leaky aquifers. The application of the method has been performed for various aquifer test data available in the groundwater literature. The results are within the practical limits of approximation compared with the unsteady state flow solutions.


1992 ◽  
Vol 26 (9-11) ◽  
pp. 2461-2464 ◽  
Author(s):  
R. D. Tyagi ◽  
Y. G. Du

A steady-statemathematical model of an activated sludgeprocess with a secondary settler was developed. With a limited number of training data samples obtained from the simulation at steady state, a feedforward neural network was established which exhibits an excellent capability for the operational prediction and determination.


2012 ◽  
Vol 22 (4) ◽  
pp. 451-465 ◽  
Author(s):  
Tadeusz Kaczorek

A new modified state variable diagram method is proposed for determination of positive realizations with reduced numbers of delays and without delays of linear discrete-time systems for a given transfer function. Sufficient conditions for the existence of the positive realizations of given proper transfer function are established. It is shown that there exists a positive realization with reduced numbers of delays if there exists a positive realization without delays but with greater dimension. The proposed methods are demonstrated on a numerical example.


2021 ◽  
Vol 11 (4) ◽  
pp. 1717
Author(s):  
Gilberto Gonzalez Avalos ◽  
Noe Barrera Gallegos ◽  
Gerardo Ayala-Jaimes ◽  
Aaron Padilla Garcia

The direct determination of the steady state response for linear time invariant (LTI) systems modeled by multibond graphs is presented. Firstly, a multiport junction structure of a multibond graph in an integral causality assignment (MBGI) to get the state space of the system is introduced. By assigning a derivative causality to the multiport storage elements, the multibond graph in a derivative causality (MBGD) is proposed. Based on this MBGD, a theorem to obtain the steady state response is presented. Two case studies to get the steady state of the state variables are applied. Both cases are modeled by multibond graphs, and the symbolic determination of the steady state is obtained. The simulation results using the 20-SIM software are numerically verified.


1981 ◽  
Vol 256 (7) ◽  
pp. 3399-3404
Author(s):  
G.L. Alonso ◽  
D.M. Arrigo ◽  
M.V. Soliz-Frieldmeier

Neurosurgery ◽  
1985 ◽  
Vol 16 (3) ◽  
pp. 336-340 ◽  
Author(s):  
Michael Kosteljanetz

Abstract Two methods for the determination of resistance to the outflow of cerebrospinal fluid, the bolus injection technique and the constant rate steady state infusion technique, were compared. Thirty-two patients with a variety of intracranial diseases (usually communicating hydrocephalus) were studied. There was a high degree of correlation between the resistance values obtained with the two methods, but values based on the bolus injection technique were systematically and statistically significantly lower than those obtained with the constant rate infusion test. From a practical point of view. both methods were found to be applicable in a clinical setting.


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