scholarly journals Lunasin: A Novel Cancer Preventive Seed Peptide

2008 ◽  
Vol 2 ◽  
pp. PMC.S372 ◽  
Author(s):  
Blanca Hernández-Ledesma ◽  
Ben O. De Lumen
Keyword(s):  
Cancer Prevention ◽  
Anticancer Activity ◽  
Protease Inhibitors ◽  
Bioactive Compounds ◽  
Lifestyle Factors ◽  
Western World ◽  
Significant Protection ◽  
Nutritional Habits ◽  
Adequate Nutrition ◽  
Causes Of Deaths

Cancer is one of the leading causes of deaths in the Western world. Approximately one-third of these deaths are preventable by lifestyle factors, including modification of nutritional habits. Studies have demonstrated that adequate nutrition with certain types of foods containing bioactive compounds might offer significant protection against carcinogenesis. Soybeans contain a variety of phytochemicals with demonstrated anticancer activity, including isoflavones, protease inhibitors, and more recently lunasin, a novel cancer preventive seed peptide. Initially isolated from soybean, lunasin has also been reported in barley and wheat. The purpose of this review is to summarize the most recent evidence on the possible benefits of lunasin for cancer prevention.

scholarly journals Importance of Nutritional Habits in Cancer Prevention: A Molecular Perspective

2021 ◽  
Vol 4 (1) ◽  
pp. 109-122
Author(s):  
Mustafa ÇELEBİER ◽  
Ayşe ERCAN ◽  
Yavuz Bülent KÖSE
Keyword(s):  
Cancer Prevention ◽  
Nutritional Habits

Cancer Prevention by Protease Inhibitors

1993 ◽  
Vol 22 (5) ◽  
pp. 796-811 ◽  
Author(s):  
A.R. Kennedy
Keyword(s):  
Cancer Prevention ◽  
Protease Inhibitors

scholarly journals Modifiable Lifestyle Factors: Opportunities for (Hereditary) Breast Cancer Prevention - a Narrative Review

Breast Care ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. 108-113 ◽  
Author(s):  
Jacqueline Lammert ◽  
Sabine Grill ◽  
Marion Kiechle
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Prevention ◽  
Healthy Lifestyle ◽  
Absolute Risk ◽  
Lifestyle Factors ◽  
Breast Cancer Prevention ◽  
The Impact

Increasing rates of obesity, lack of physical activity, sedentary behavior, and frequent alcohol consumption are major lifestyle-related risk factors for breast cancer. In fact, it has been estimated that about one-third of breast cancer cases are attributable to factors women can change. Most research has focused on examining the impact of one single exposure on breast cancer risk while adjusting for other risk modifiers. Capitalizing on big data, major efforts have been made to evaluate the combined impact of well-established lifestyle factors on overall breast cancer risk. At the individual level, data indicate that even simple behavior modifications could have a considerable impact on breast cancer prevention. Moreover, there is emerging new evidence that adopting a healthy lifestyle may be particularly relevant for women with hereditary susceptibility to breast cancer. On the absolute risk scale, studies suggest that the presence of certain risk factors, such as excessive body weight, had a substantially higher impact on breast cancer risk if women had a hereditary predisposition to cancer. The existing body of knowledge gives the medical professionals guidance as to which factors to focus on when counseling patients. However, well-designed randomized controlled trials utilizing objective methods are crucial to providing concrete recommendations.

Bioactive compounds obtained by immobilisation of serine protease inhibitors

2011 ◽  
Vol 3 (4) ◽  
pp. 335
Author(s):  
Mihaela Carmen Eremia ◽  
Irina Lupescu ◽  
Luminita Tcacenco
Keyword(s):  
Serine Protease ◽  
Protease Inhibitors ◽  
Bioactive Compounds ◽  
Serine Protease Inhibitors

scholarly journals Recent study on the anticancer activity of nobiletin and its metabolites

2021 ◽  
Vol 14 ◽  
Author(s):  
Ke Lv ◽  
Lingling Zhang ◽  
Hui Zhao ◽  
Chi-Tang Ho ◽  
Shiming Li
Keyword(s):  
Cancer Prevention ◽  
Anticancer Activity ◽  
Promising Candidate ◽  
Naturally Occurring ◽  
Antitumor Potential ◽  
Anti Cancer ◽  
Citrus Peels ◽  
Derivatives Of ◽  
Cancer Activity

The exploration of naturally occurring phytochemicals with antitumor potential has been the focus of many studies. Nobiletin, a polymethoxyflavone (PMF) exclusively derived from citrus peels, has been reported as a promising candidate for the prevention and/or treatment of cancers. Additionally, multiple demethylated derivatives of nobiletin from in vivo biotransformation, including 3′-demethylnobiletin (3′-DMN), 4′-demethylnobiletin (4′-DMN), 3′,4′-didemethylnobiletin (3′,4′-DDMN) and 5-demethylnobiletin (5-DMN), among others, have been found to show anti-cancer activity. In this review, the anticancer activity of nobiletin and its derivatives in cancer prevention are comprehensively described.

scholarly journals Anticancer Activity of Natural Bioactive Compounds against Human Carcinoma Cell Lines - A mini review

2019 ◽  
Vol 24 (6) ◽  
pp. 937-944 ◽  
Author(s):  
SAHIBZADA SHAKIR REHMAN ◽  
◽  
AISHA ASHRAF ◽  
ZILL-I-HUMA NAZLI ◽  
ABIDA KAUSAR ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
Bioactive Compounds ◽  
Carcinoma Cell ◽  
Human Carcinoma ◽  
Carcinoma Cell Lines ◽  
Human Carcinoma Cell
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