The impact of European vaccination policies on seasonal influenza vaccination coverage rates in the elderly

Abstract Background Seasonal influenza vaccination (SIV) of health care workers (HCWs) is well recognized as a public health measure that can protect both HCWs from infection and patients from the risk of influenza complications. Nevertheless, vaccination coverage rates among this specific population result generally lower than the recommended target. With our study, we aimed to describe the activities and the outcomes of four different SIV campaigns targeted at HCWs and organized during the season 2018/2019 in four hospitals in Rome. Methods A cross-sectional study involving four teaching hospitals was performed. The collected data were synthetized into a set of descriptors and indicators, validated through a previous study that had involved the same Centers. Results The Medical Directorates, in collaboration with the University Hygiene and Public Health Units of the four hospitals organized different strategies: Hospital 1, 3 and 4 realized educational courses for HCWs and actively promoted the campaigns through e-mail invitations to all HCWs. As for the access to vaccination, all the hospitals provided a dedicated unit for SIV; Hospital 1 and Hospital 4 organized also on-site vaccination sessions in the hospital wards, that required a large number of staff. The vaccination coverage rates resulted: 22.37% in Hospital 1, 18.10% in Hospital 4, 9.28% in Hospital 2 and 8,51% in Hospital 3. Conclusions Our results demonstrate that multi-activity campaigns, involving education, promotion and easy access to vaccination constitute an effective approach to reinforce the value of SIV. Our findings suggest that on-site vaccination may play a key role in determining a higher vaccination coverage. Key messages Multi-activity vaccination campaigns, involving education, promotion and easy access to vaccination constitute an effective approach to reinforce the value of seasonal influenza vaccination for HCWs. On-site vaccination may play a key role in determining a higher vaccination coverage.

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2005 and 2006 seasonal influenza vaccination coverage rates in 10 countries in Africa, Asia Pacific, Europe, Latin America and the Middle East

Journal of Public Health Policy ◽

10.1057/jphp.2008.40 ◽

2009 ◽

Vol 30 (1) ◽

pp. 83-101 ◽

Cited By ~ 34

Author(s):

Camille de Lataillade ◽

Stéphane Auvergne ◽

Isabelle Delannoy

Keyword(s):

Latin America ◽

Middle East ◽

Influenza Vaccination ◽

Vaccination Coverage ◽

Seasonal Influenza ◽

Asia Pacific ◽

Seasonal Influenza Vaccination ◽

Coverage Rates

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The Impact of Missed Opportunities on Seasonal Influenza Vaccination Coverage for Healthy Young Children

Journal of Public Health Management and Practice ◽

10.1097/phh.0b013e31821831c3 ◽

2011 ◽

Vol 17 (6) ◽

pp. 560-564 ◽

Cited By ~ 14

Author(s):

Norma J. Allred ◽

Katherine A. Poehling ◽

Peter G. Szilagyi ◽

Fan Zhang ◽

Kathryn M. Edwards ◽

...

Keyword(s):

Young Children ◽

Influenza Vaccination ◽

Vaccination Coverage ◽

Seasonal Influenza ◽

Missed Opportunities ◽

Seasonal Influenza Vaccination ◽

The Impact

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Impact of European vaccination policies on seasonal influenza vaccination coverage rates: An update seven years later

Human Vaccines & Immunotherapeutics ◽

10.1080/21645515.2018.1489948 ◽

2018 ◽

pp. 1-9 ◽

Cited By ~ 2

Author(s):

Patricia R. Blank ◽

Gerrit Adrianus van Essen ◽

Raúl Ortiz de Lejarazu ◽

Jan Kyncl ◽

Aneta Nitsch-Osuch ◽

...

Keyword(s):

Influenza Vaccination ◽

Vaccination Coverage ◽

Seasonal Influenza ◽

Seasonal Influenza Vaccination ◽

Coverage Rates

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2742. The Impact of Influenza Vaccination on Antibiotic Use in the United States, 2010–2017

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.2419 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S965-S966

Author(s):

Eili Klein ◽

Emily Schueller ◽

Katie K Tseng ◽

Arindam Nandi

Keyword(s):

United States ◽

Antibiotic Resistance ◽

Influenza Vaccination ◽

Vaccination Coverage ◽

Seasonal Influenza ◽

Antibiotic Use ◽

The United States ◽

Antibiotic Prescribing ◽

Coverage Rates ◽

The Impact

Abstract Background Antibiotic resistance is a cause of morbidity and mortality driven by inappropriate prescribing. In the United States, a third of all outpatient antibiotic prescriptions may be inappropriate. Seasonal influenza rates are significantly associated with antibiotic prescribing rates. The impact of influenza vaccination coverage on antibiotic prescribing is unknown. Methods We conducted a retrospective analysis of state-level vaccination coverage and antibiotic prescribing rates from 2010 to 2017. We used fixed effects regression to analyze the relationship between cumulative vaccine coverage rates for a season and the per capita number of prescriptions for systemic antibiotics for the corresponding season (January–March) controlling for temperature, poverty, healthcare infrastructure, population structure, and vaccine effectiveness. Results Rates of vaccination coverage ranged from 33% in Nevada to 52% in Rhode Island for the 2016–2017 season, while antibiotic use rates ranged from 25 prescriptions per 1,000 inhabitants in Alaska to 377 prescriptions per 1,000 inhabitants in West Virginia (Figure 1). Vaccination coverage rates were highly correlated with reduced prescribing rates, and controlling for other factors, we found that a one percent increase in the influenza vaccination rate was associated with 1.40 (95% CI: 2.22–0.57, P < 0.01) fewer antibiotic prescriptions per 1,000 inhabitants (Table 1). Increases in the vaccination coverage rate in the pediatric population (aged 0–18) had the strongest effect, followed by the elderly (aged 65+). Conclusion Vaccination can reduce morbidity and mortality from seasonal influenza. Though coverage rates are far below levels necessary to generate herd immunity, we found that higher coverage rates in a state were associated with lower antibiotic prescribing rates. While the effectiveness of the vaccine varies from year to year and the factors that drive antibiotic prescribing rates are multi-factorial, these results suggest that increased vaccination coverage for influenza would have significant benefit in terms of reducing antibiotic overuse and correspondingly antibiotic resistance. Disclosures All authors: No reported disclosures.

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Impact of national influenza vaccination strategy in severe influenza outcomes among the high-risk Portuguese population

BMC Public Health ◽

10.1186/s12889-019-7958-8 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 1

Author(s):

Ausenda Machado ◽

Irina Kislaya ◽

Amparo Larrauri ◽

Carlos Matias Dias ◽

Baltazar Nunes

Keyword(s):

High Risk ◽

Influenza Vaccination ◽

Seasonal Influenza ◽

Vaccine Coverage ◽

Vaccination Strategy ◽

High Risk Population ◽

Risk Population ◽

Seasonal Influenza Vaccination ◽

Severe Influenza ◽

The Impact

Abstract Background All aged individuals with a chronic condition and those with 65 and more years are at increased risk of severe influenza post-infection complications. There is limited research on cases averted by the yearly vaccination programs in high-risk individuals. The objective was to estimate the impact of trivalent seasonal influenza vaccination on averted hospitalizations and death among the high-risk population in Portugal. Methods The impact of trivalent seasonal influenza vaccination was estimated using vaccine coverage, vaccine effectiveness and the number of influenza-related hospitalizations and deaths. The number of averted events (NAE), prevented fraction (PF) and number needed to vaccinate (NVN) were estimated for seasons 2014/15 to 2016/17. Results The vaccination strategy averted on average approximately 1833 hospitalizations and 383 deaths per season. Highest NAE was observed in the ≥65 years population (85% of hospitalizations and 95% deaths) and in the 2016/17 season (1957 hospitalizations and 439 deaths). On average, seasonal vaccination prevented 21% of hospitalizations in the population aged 65 and more, and 18.5% in the population with chronic conditions. The vaccination also prevented 29% and 19.5% of deaths in each group of the high-risk population. It would be needed to vaccinate 3360 high-risk individuals, to prevent one hospitalization and 60,471 high-risk individuals to prevent one death. Conclusion The yearly influenza vaccination campaigns had a sustained positive benefit for the high-risk population, reducing hospitalizations and deaths. These results can support public health plans toward increased vaccine coverage in high-risk groups.

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