scholarly journals Prevalence of the Metabolic Syndrome among North Indian Adolescents Using Adult Treatment Panel III and Pediatric International Diabetic Federation Definitions

2014 ◽  
Vol 05 (03) ◽  
Author(s):  
Zeeshan Ahmad
Keyword(s):  
Metabolic Syndrome ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
Indian Adolescents ◽  
The Metabolic Syndrome

scholarly journals TSH and free thyroxine concentrations are associated with differing metabolic markers in euthyroid subjects

2010 ◽  
Vol 163 (2) ◽  
pp. 273-278 ◽  
Author(s):  
Jose de Jesus Garduño-Garcia ◽  
Ulices Alvirde-Garcia ◽  
Guadalupe López-Carrasco ◽  
Ma Elena Padilla Mendoza ◽  
Roopa Mehta ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Total Cholesterol ◽  
Thyroid Function ◽  
Free Thyroxine ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
Positive Correlation ◽  
The Metabolic Syndrome

ObjectiveTo examine the association between thyroid function and the components of the metabolic syndrome and insulin resistance in an Hispanic population.DesignCross-sectional study.MethodsSubjects with no history of thyroid disease or diabetes were included. Thyroid function was stratified as euthyroid or subclinical hypothyroidism (SCH) status and subsequently by free thyroxine (FT4) and TSH tertiles. The association of the metabolic syndrome components (defined by 2004 Adult Treatment Panel III criteria) and insulin resistance with thyroid status, TSH, and FT4 were examined.ResultsA total of 3148 subjects were analyzed. The prevalence of SCH was 8.3%. The prevalence of the metabolic syndrome was similar in euthyroid and SCH patients (31.6 vs 32.06%, P=0.89). Total cholesterol was higher in patients with SCH (5.51±1.19 vs 5.34±1.05 mmol/l, P<0.032). Serum TSH values showed a positive correlation (adjusted for age and sex) with total cholesterol, triglycerides, and waist circumference. In contrast, FT4 showed a positive correlation with high-density lipoprotein cholesterol, and an inverse correlation with waist circumference, insulin, and HOMA-IR.ConclusionSCH is not associated with an increased risk for the metabolic syndrome (as conceived as a diagnostic category defined by the National Cholesterol, Education Program, Adult Treatment Panel III criteria). Despite this, low thyroid function (even in the euthyroid state) predisposes to higher cholesterol, glucose, insulin, and HOMA-IR levels. The combined use of TSH and FT4, compared with the assessment based on only FT4, is a more convenient approach to evaluate the association between thyroid function and metabolic variables.

scholarly journals Relationship to Insulin Resistance of the Adult Treatment Panel III Diagnostic Criteria for Identification of the Metabolic Syndrome

Diabetes ◽  
2004 ◽  
Vol 53 (5) ◽  
pp. 1195-1200 ◽  
Author(s):  
K. L. Cheal ◽  
F. Abbasi ◽  
C. Lamendola ◽  
T. McLaughlin ◽  
G. M. Reaven ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Diagnostic Criteria ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
The Metabolic Syndrome

scholarly journals Síndrome metabólico: concepto y aplicación práctica

2014 ◽  
Vol 74 (4) ◽  
pp. 315 ◽  
Author(s):  
Juan Carlos Lizarzaburu Robles
Keyword(s):  
Metabolic Syndrome ◽  
Education Program ◽  
National Cholesterol Education Program ◽  
International Diabetes Federation ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
The Metabolic Syndrome ◽  
Tejido Adiposo ◽  
Síndrome Metabólico ◽  
America Latina

El síndrome metabólico (SM) es un conjunto de anormalidades metabólicas consideradas como un factor de riesgo para desarrollar enfermedad cardiovascular y diabetes. Los componentes del SM se han definido según diferentes guías y consensos. Las definiciones propuestas por el National Cholesterol Education Program Adult Treatment Panel III (ATP III) y la International Diabetes Federation (IDF) son las más utilizadas en las diferentes publicaciones; sin embargo, se han realizado actualizaciones para diferentes poblaciones según la etnia y ubicación geográfica, como es el caso de la Asociación Latinoamericana de Diabetes (ALAD), que define un perímetro abdominal determinado para la región América Latina. En el año 2009, la publicación Harmonizing the Metabolic Syndrome sugirió un consenso para el diagnóstico de SM tratando de unificar los criterios de las diferentes organizaciones. Respecto a la fisiopatología del SM, la resistencia a insulina ha sido considerada como base del desarrollo del conjunto de anormalidades que lo conforman, sugiriendo a la obesidad abdominal o central como responsable del desarrollo de la insulino resistencia. Las adipoquinas producidas por el tejido adiposo abdominal actuarían directa o indirectamente en el desarrollo de los componentes del síndrome. Es importante mencionar que el síndrome metabólico ha sido considerado un equivalente diagnóstico de prediabetes, por ser predictor de diabetes. El incremento en la prevalencia del SM a nivel mundial le ha otorgado una gran importancia en la prevención y control de riesgo de la enfermedad cardiovascular y la diabetes. En el presente artículo revisaremos importantes aspectos sobre la definición y diagnóstico del síndrome metabólico.

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