Harmonizing the Definition of the Metabolic Syndrome: Comparison of the Criteria of the Adult Treatment Panel III and the International Diabetes Federation in United States American and European Populations

2007 ◽  
Vol 99 (4) ◽  
pp. 541-548 ◽  
Author(s):  
Gerd Assmann ◽  
Rudy Guerra ◽  
Garrett Fox ◽  
Paul Cullen ◽  
Helmut Schulte ◽  
...  
Keyword(s):  
United States ◽  
Metabolic Syndrome ◽  
International Diabetes Federation ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
The Metabolic Syndrome ◽  
Definition Of ◽  
European Populations

scholarly journals Síndrome metabólico: concepto y aplicación práctica

2014 ◽  
Vol 74 (4) ◽  
pp. 315 ◽  
Author(s):  
Juan Carlos Lizarzaburu Robles
Keyword(s):  
Metabolic Syndrome ◽  
Education Program ◽  
National Cholesterol Education Program ◽  
International Diabetes Federation ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
The Metabolic Syndrome ◽  
Tejido Adiposo ◽  
Síndrome Metabólico ◽  
America Latina

El síndrome metabólico (SM) es un conjunto de anormalidades metabólicas consideradas como un factor de riesgo para desarrollar enfermedad cardiovascular y diabetes. Los componentes del SM se han definido según diferentes guías y consensos. Las definiciones propuestas por el National Cholesterol Education Program Adult Treatment Panel III (ATP III) y la International Diabetes Federation (IDF) son las más utilizadas en las diferentes publicaciones; sin embargo, se han realizado actualizaciones para diferentes poblaciones según la etnia y ubicación geográfica, como es el caso de la Asociación Latinoamericana de Diabetes (ALAD), que define un perímetro abdominal determinado para la región América Latina. En el año 2009, la publicación Harmonizing the Metabolic Syndrome sugirió un consenso para el diagnóstico de SM tratando de unificar los criterios de las diferentes organizaciones. Respecto a la fisiopatología del SM, la resistencia a insulina ha sido considerada como base del desarrollo del conjunto de anormalidades que lo conforman, sugiriendo a la obesidad abdominal o central como responsable del desarrollo de la insulino resistencia. Las adipoquinas producidas por el tejido adiposo abdominal actuarían directa o indirectamente en el desarrollo de los componentes del síndrome. Es importante mencionar que el síndrome metabólico ha sido considerado un equivalente diagnóstico de prediabetes, por ser predictor de diabetes. El incremento en la prevalencia del SM a nivel mundial le ha otorgado una gran importancia en la prevención y control de riesgo de la enfermedad cardiovascular y la diabetes. En el presente artículo revisaremos importantes aspectos sobre la definición y diagnóstico del síndrome metabólico.

scholarly journals Prevalence of the metabolic syndrome diagnosed using three different definitions and risk of ischemic heart disease among Kaunas adult population

Medicina ◽  
2010 ◽  
Vol 46 (1) ◽  
pp. 61 ◽  
Author(s):  
Dalia Lukšienė ◽  
Miglė Bacevičienė ◽  
Abdonas Tamošiūnas ◽  
Liucija Černiauskienė ◽  
Lilija Margevičienė ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
International Diabetes Federation ◽  
Ischemic Heart ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
International Diabetes Federation Definition ◽  
The Metabolic Syndrome ◽  
The World

The aim of this study was to compare the prevalence of the metabolic syndrome diagnosed using three different definitions and to evaluate its associations with ischemic heart disease in Kaunas adult population. Material and methods. Data of preventive screening carried out in Kaunas in 2001–2002 according to the MONICA study protocol were used for analysis; a total of 1336 persons aged 35–64 years (603 men and 733 women) were recruited. The metabolic syndrome was defined by the World Health Organization, Adult Treatment Panel III, and International Diabetes Federation definitions. Ischemic heart disease was diagnosed based on the following criteria: a documented history of myocardial infarction, angina pectoris, or ischemic changes on electrocardiogram. Results. The metabolic syndrome was identified for 11.3% of men and for 9.4% of women using the World Health Organization definition, for 19.4% of men and for 26.3% of women using the Adult Treatment Panel III definition, and for 30.0% of men and for 37.7% of women using the International Diabetes Federation definition. In male and female groups, the prevalence of the metabolic syndrome (irrespective of definition) significantly increased with age (P<0.05). After adjusting for age, men diagnosed with the metabolic syndrome using the International Diabetes Federation definition (OR=2.30; P=0.001) and Adult Treatment Panel III definition (OR=1.97; P=0.01) and women diagnosed with metabolic syndrome using the International Diabetes Federation definition (OR=1.50; P=0.039) had a significantly higher risk of having ischemic heart disease as compared with those without the metabolic syndrome by the same definitions. The metabolic syndrome diagnosed using the World Health Organization definition was not associated with a significant risk of ischemic heart disease in men and women. Conclusion. In Kaunas population aged 35–64 years, the highest prevalence of the metabolic syndrome was determined according to the International Diabetes Federation definition. Usage of the International Diabetes Federation and the Adult Treatment Panel III definitions in establishing diagnosis of the metabolic syndrome provides more opportunities to identify subjects with ischemic heart disease.

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