Occupational exposure influences control of disease in patients with chronic rhinosinusitis

2021 ◽  
Vol 59 (4) ◽  
pp. 380-386
Author(s):  
D.A.E. Dietz de Loos ◽  
S. Ronsmans ◽  
M.E. Cornet ◽  
P.W. Hellings ◽  
V. Hox ◽  
...  

Background: Chronic rhinosinusitis (CRS) is a frequent condition that is treated by endoscopic sinus surgery (ESS) when medical treatment fails. Irritating or sensitizing airborne agents can contribute to uncontrolled CRS. A prior study showed a linear correlation between occupational exposure and the number of ESS. Methods: In this cross-sectional study we tested the hypothesis that occupational exposure is a risk for undergoing ESS. We sent questionnaires enquiring occupational exposure in patients with CRS with nasal polyps (CRSwNP) or CRS without nasal polyps (CRSsNP). An expert assessed blindly the reported work exposures to inhaled agents. The relationship between occupational exposure on undergoing ESS was analysed. Results: Among all patients who underwent ESS (n=343), 30% reported a relevant occupational exposure, which is significantly higher than the 4.8% found among CRS patients that underwent no prior sinus surgery (n=21). Besides occupational exposure, self-reported doctor-diagnosed asthma were independent variables contributing to the chance of undergoing ESS. Conclusion: In our study we confirm occupational exposure as a risk factor for uncontrolled CRS, if defined by undergoing ESS. In CRS patients with uncontrolled symptoms, despite maximal conservative therapy, the clinician should explore the possible contribution of occupational exposure.

2005 ◽  
Vol 29 (4) ◽  
pp. 357-362 ◽  
Author(s):  
Ana Estela Haddad ◽  
Maria Salete Nahás Pires Correa

The objective of this study is to determine the correlation between the number of erupted primary teeth, the age, sex and the somatic measures of weight and height (length) in a Brazilian population based cross sectional study. A systematic sampling was used. Complete and consistent data were obtained from 870 of a total of 908 children from birth to 36 months of age. Statistical analysis comprised a multiple regression equation, where the number of erupted primary teeth was modeled as the dependent variable and the initial specification included the following independent variables: age, sex, birth-length, birth-weight, weight and length measured at the examination of the child. Results showed that in this study, 86% of the variation of the number of erupted primary teeth was explained by age and height of children (p<0.001). Age and height showed a stronger correlation with the number of erupted primary teeth than all the tested variables together. It was concluded that primary teeth eruption is highly influenced by age and height (length) of the child. Using the best regression equation found, a chart was constructed where the variation of the number of erupted primary teeth is given according to age and height of the child.


2020 ◽  
pp. 341-348

Background. The determination of farmers' knowledge and attitudes towards pesticide use is very important in terms of preventing pesticide use-related short- and long-term damages. Objective. This study was aimed at investigating the relationship between the sociodemographic characteristics of farmers in Karacabey District of Bursa, a province in northwest Turkey, and their knowledge and attitudes towards pesticide use. Material and methods. This cross-sectional study was conducted in Karacabey district between December 2018 and April 2019. The sample size was calculated as 1924 using the Epi info program by assuming the prevalence as 50%, type I error as 5%, standard deviation as 3% and design effect as 2. The dependent variable of the study was the farmers' knowledge of and attitudes towards pesticide use whereas the independent variables were their sociodemographic characteristics. The relationship between the dependent and independent variables was analyzed using the chi-square test and binary logistic regression model. Results. The mean score the participants obtained from the Knowledge and Attitude Index was 12.8±2.8 and the median value was 13. While 49.5% of the participating farmers obtained a score lower than the median, 51.5% of them obtained a score equal to or above the median. While advanced age increased the possibility of getting a low score from the Knowledge and Attitude Index 2.7 times, not being married increased it 35.7 times, not getting formal education increased it 30.1 times, living in a non-crowded household increased it 2.1 times, and low income (2000 Turkish liras equal to ≤$310 according to April 2019 exchange rates) increased it 3.1 times. Conclusion. The study indicated that the participating farmers’ knowledge and attitudes towards the proper use of pesticides were inadequate, and that there was a strong relationship between their Knowledge and Attitude Index scores and their sociodemographic characteristics.


2019 ◽  
Vol 14 (1) ◽  
pp. 13
Author(s):  
Fajar Afrindo ◽  
Merryana Adriani

Physical fitness is the basic capital of a person to perform physical activities efficiently in a long time without fatigue with adequate rest. Good physical fitness can be very influential on the work activities of respondents, and it is also very important for human life. This study aims to analyze the relationship between consuming supplements and nutritional status on the members of Tivoli fitness center in Sidoarjo. The type of the study used in this study was a quantitative approach with Cross Sectional study. This study employed quantitative approach with cross sectional study where each of the respondents was observed or interviewed for once, and dependent and independent variables were observed or interviewed at the same time or following on observation time status. Further, this study applied simple random sampling with sample list of male member respondents in Tivoli fitness center. Variables in this study were independent variables consisting of respondent characteristic, level of knowledge and consumption pattern, and a dependent variable that was physical fitness. Data analysis was done by using statistic test. The results of this study showed that respondents who consumed more supplementshad higher fitness level in which they felt fitter compared to the respondents who did not consume supplements. The result of chi square statistic test from fisher's exact test obtained p value of 0.716. The p value is > 0.05. It can be concluded from the study that consumption of supplements showed no statistically significant relationship with the physical fitness ofthe members of Tivoli fitness center in Sidoarjo.


2014 ◽  
Vol 7 (3) ◽  
pp. 100-104 ◽  
Author(s):  
Anilkumar Suryadev Harugop ◽  
Ramesh Mudhol ◽  
Amit Nargund ◽  
Shailaja Hugar ◽  
Amrit Kapoor ◽  
...  

ABSTRACT Objective To determine whether topical application of mitomycin- C at the conclusion of FESS decreases the incidence of postoperative adhesion formation. Study design Prospective cross-sectional study. Materials and methods Between June 2011 and June 2013, 42 patients (65 sides) aged between 16 and 66 years diagnosed to have chronic rhinosinusitis (CRS) underwent FESS. At the conclusion of the ESS, cotton ribbon wick soaked with 1 ml mitomycin-C (0.4 mg/ml) was placed in right/left/ both middle meati, near the widened sinus ostia for a period of 4 minutes. Following application, nasal cavity was irrigated with sterile normal saline. Patients were examined weekly for 1 month after surgery. Additional examinations were done at the end of 2nd and 3rd months postoperatively. At the end of 3 months follow-up, the outcome was assessed subjectively by symptoms and objectively by endoscopic findings. Results At the end of 3 months follow-up, a significant decrease (80%) in symptom scores was observed (6.64 ± 1.80, p < 0.001). Similarly in sinonasal outcome test (SNOT) score we observed a significant reduction (71%) in scores (17.76 ± 8.17, p < 0.001) and 3.1% cases showed adhesions. Conclusion CRS patients have remarkable improvement in their symptoms after FESS. Topical application of mitomycin-C at the conclusion of FESS/ESS has a role in prevention of adhesion formation. How to cite this article Harugop AS, Mudhol R, Nargund A, Hugar S, Kapoor A, Shetty R. Efficacy of Mitomycin-C for Prevention of Adhesion Formation after Functional Endoscopic Sinus Surgery in Cases of Chronic Rhinosinusitis: A Prospective Cross-sectional Study. Clin Rhinol An Int J 2014;7(3):100-104.


2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Mohammad Nabavi ◽  
Saba Arshi ◽  
Mohammadhasan Bemanian ◽  
Morteza Fallahpour ◽  
Mehdi Torabizadeh

Background: Rhinosinusitis is a nasal and paranasal sinus infection. Chronic infection and allergies are two major causes of nasal polyp formation. Objectives: In this study, we examined the relationship between NO and aeroallergens to determine the relationship between exhaled nitric oxide level and sensitivity to aeroallergens in chronic rhinosinusitis with nasal polyps (CRSwNP) patients referring to Hazrat Rasool Hospital in Tehran from December 2016 to May 2017. Methods: A cross-sectional study was conducted on 72 patients. The prick test and exhaled NO measurements were done to determine allergens in CRSwNP patients. Statistical analysis was done to determine the relationship between the allergy and sensitivity to indoor aeroallergens in patients with CRSwNP. Results: The correlation coefficient of. 0.014 and 0.001 were evaluated for Mosquito and Cockroach respectfully, which were significantly correlated with nitric oxide. The less correlation with nitric oxide was 0.003, which was evaluated for MUCOR. Conclusions: This study showed that most people with CRSwNP had a sensitivity to at least one indoor aeroallergen, and cockroaches were the most common allergen in patients with CRSwNP with a 17.9% prevalence. This study showed that the correlation of FeNO with the sensitivity of these patients to home aeroallergens can be used, and this correlation for mosquito and cockroach aeroallergens is very valuable. The NO level and prick testing of aeroallergens can be used to estimate the relapse or lack of appropriate response to medical treatment in patients with CRSwNP.


2019 ◽  
Vol 64 ◽  
pp. 43-47 ◽  
Author(s):  
D.P. Migueis ◽  
G.C.B. Lacerda ◽  
M.C. Lopes ◽  
L.M.S.F. Azevedo-Soster ◽  
L.C.S. Thuler ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Pascale Audrey Moriconi ◽  
Louise Nadeau

This study compares the relationship between drinking profiles and self-rated health with and without adjusting for other determinants of health among a sample of older adults from the general population. Respondents were 1,494 men and 2,176 women aged between 55 and 74 from the GENACIS Canadian survey. The dependent variable was self-rated health, an individual’s perception of his or her own general health, a measure used as a proxy for health status. The independent variables were drinking profiles (types of drinkers and nondrinkers) as well as other demographic, psychosocial, and health-related variables (control variables). After adjustment for other determinants of health, regression analyses showed that (1) frequent/moderate drinkers were more likely to have a better self-rated health compared with nondrinkers (lifetime abstainers and former drinkers) and (2) self-rated health did not differ significantly between frequent/moderate drinkers and other types of drinkers (frequent/nonmoderate and infrequent drinkers). Our results suggest that drinking is related to a better self-rated health compared with nondrinking regardless of the drinking profile. Drinking and healthy lifestyle guidelines specific to older adults should be studied, discussed, and integrated into public health practices.


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