scholarly journals Utilization of Digoxin among Hospitalized Elderly Patients with Heart Failure and Atrial Fibrillation in Thailand: Prevalence, Associated factors, and Clinical Outcomes

2021 ◽  
Author(s):  
Noppaket Singkham ◽  
Yuttana Wongsalap ◽  
Duangkamon Poolpun ◽  
Sirichok Phetnoo ◽  
Chuthalak Somkhon
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Elderly Patients ◽  
Clinical Outcomes ◽  
Associated Factors ◽  
Hospitalized Elderly ◽  
Patients With Heart Failure ◽  
Hospitalized Elderly Patients

scholarly journals Relationship between Activities of Daily Living and Readmission within 90 Days in Hospitalized Elderly Patients with Heart Failure

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Masahiro Kitamura ◽  
Kazuhiro P. Izawa ◽  
Hiroki Taniue ◽  
Yumi Mimura ◽  
Keita Imamura ◽  
...  
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
Elderly Patients ◽  
Activities Of Daily Living ◽  
Roc Curve ◽  
Daily Living ◽  
Cutoff Value ◽  
Hospitalized Elderly ◽  
Patients With Heart Failure ◽  
Hospitalized Elderly Patients

Aims. To examine the relationship between activities of daily living (ADL) and readmission within 90 days and assess the cutoff value of ADL to predict readmission in hospitalized elderly patients with heart failure (HF). Methods. This cohort study comprised 589 consecutive patients with HF aged ≥65 years, who underwent cardiac rehabilitation from May 2012 to May 2016 and were discharged home. We investigated patients’ characteristics, basic attributes, and ADL (motor and cognitive Functional Independence Measure [FIM]). We analyzed the data using the unpaired t-test, χ2 test, Cox proportional hazard model, receiver operating characteristic (ROC) curve, and Kaplan-Meier method. Results. Of 589 patients, 113 met the criteria, and they were divided into the nonreadmission (n=90) and readmission groups (n=23). Age, body mass index, New York Heart Association class, hemoglobin level, and motor FIM score were significantly different between the two groups (p<0.05). The body mass index (hazard ratio [HR]: 0.87; p<0.05) and motor FIM score (HR: 0.94; p<0.01) remained statistically significant. The cutoff value for the motor FIM score determined by ROC curve analysis was 74.5 points (area under the curve = 0.78; p<0.001). Conclusion. The motor FIM score in elderly patients with HF was an independent predictor of rehospitalization within 90 days.

Impact of Physical Function and Exercise Capacity on the Outcomes In Hospitalized Elderly Patients with Acute Heart Failure

2020 ◽  
Vol 26 (10) ◽  
pp. S114
Author(s):  
Takeshi Kitai ◽  
Takayuki Shimogai ◽  
Kentaro Iwata ◽  
Andrew Xanthopoulos ◽  
Shuichiro Kaji ◽  
...  
Keyword(s):  
Heart Failure ◽  
Elderly Patients ◽  
Physical Function ◽  
Acute Heart Failure ◽  
Exercise Capacity ◽  
Hospitalized Elderly ◽  
Hospitalized Elderly Patients

Effect of nebivolol on outcome in elderly patients with heart failure and atrial fibrillation: insights from SENIORS

2012 ◽  
Vol 14 (10) ◽  
pp. 1171-1178 ◽  
Author(s):  
Bart A. Mulder ◽  
Dirk J. van Veldhuisen ◽  
Harry J.G.M. Crijns ◽  
Michael Böhm ◽  
Alain Cohen-Solal ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Elderly Patients ◽  
Patients With Heart Failure

scholarly journals Efficacy of Tolvaptan in Elderly Patients with Heart Failure and Preserved Ejection Fraction

2019 ◽  
Vol 5 (2) ◽  
pp. 59-65
Author(s):  
Yoriyasu Suzuki ◽  
Akira Murata ◽  
Satoshi Tsujimoto ◽  
Yusuke Ochiumi ◽  
Tatsuya Ito
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Elderly Patients ◽  
Hospital Stay ◽  
Clinical Outcomes ◽  
Rest Period ◽  
Length Of Hospital Stay ◽  
Bed Rest ◽  
Preserved Ejection Fraction ◽  
Patients With Heart Failure

Abstract Background: There is no known therapy with proven efficacy for improving clinical outcomes in elderly patients with heart failure (HF) and preserved ejection fraction (HFpEF). In this study, we aimed to evaluate the efficacy of tolvaptan (TLV) in elderly HFpEF patients. Methods: This retrospective observational study involved 100 consecutive elderly HFpEF patients hospitalized at the Nagoya Heart Center, Japan. Inclusion criteria were: (1) patients aged ≥75 years; (2) first hospitalization secondary to HF; (3) received medical therapy for HF, without invasive treatment; and (4) clinical follow-up for >6 months after discharge. The primary endpoint was rehospitalization due to worsening HF, and the secondary endpoint was worsening renal function (WRF) during hospitalization and at 6 months after discharge. Sixty background-matched HFpEF patients were divided into 2 groups: with TLV therapy (TLV (+), n = 29) and without TLV therapy (TLV (–), n = 31). In the TLV (+) group, TLV therapy was continued after discharge. Clinical outcomes of these patients were evaluated. Results: Bed rest period and length of hospital stay were significantly shorter in the TLV (+) group than in the TLV (−) group. The dose of loop diuretics, mean serum creatinine levels, and incidence of WRF development were significantly lower in the TLV (+) group. Incidence of rehospitalization was also significantly lower in the TLV (+) group (log-rank test; p = 0.018). The multivariate logistic regression analysis demonstrated that TLV therapy reduces the incidence of rehospitalization in elderly patients with HFpEF. Conclusions: TLV therapy reduced the bed rest period, length of hospital stay, and rate of rehospitalization without WRF in elderly HFpEF patients, suggesting that TLV could represent an effective therapy for this group of patients.

P6356Comparisons of clinical outcomes in patients with heart failure with preserved ejection fraction with and without atrial fibrillation: results from a multicenter PURSUIT-HFpEF registry

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Masuda ◽  
T Kanda ◽  
M Asai ◽  
T Mano ◽  
T Yamada ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Ejection Fraction ◽  
Clinical Outcomes ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Preserved Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
Heart Failure Patients ◽  
Patients With Heart Failure

Abstract Background The presence of atrial fibrillation (AF) has been demonstrated to be associated with poor clinical outcomes in heart failure patients with reduced ejection fraction. Objective This study aimed to elucidate the impact of the presence of atrial fibrillation (AF) on the clinical characteristics, therapeutics, and outcomes in patients with heart failure and preserved ejection fraction (HFpEF). Methods PURSUIT-HFpEF is a multicenter prospective observational study including patients hospitalized for acute heart failure with left ventricular ejection fraction of >50%. Patients with acute coronary syndrome or severe valvular disease were excluded. Results Of 486 HFpEF patients (age, 80.8±9.0 years old; male, 47%) from 24 cardiovascular centers, 199 (41%) had AF on admission. Patients with AF had lower systolic blood pressures (142±27 vs. 155±35mmHg, p<0.0001) and higher heart rates (91±29 vs. 82±26bpm, p<0.0001) than those without. There was no difference in the usage of inotropes or mechanical ventilation between the 2 groups. A higher quality of life score (EQ5D, 0.72±0.27 vs. 0.63±0.30, p=0.002) was observed at discharge in patients with than without AF. In addition, AF patients tended to demonstrate lower in-hospital mortality rates (0.5% vs. 2.4%, p=0.09) and shorter hospital stays (20.3±12.1 vs. 22.6±18.4 days, p=0.09) than those without. During a mean follow up of 360±111 days, mortality (14.1% vs. 15.3) and heart failure re-hospitalization rates (13.1% vs. 13.9%) were comparable between the 2 groups. Conclusion In contrast to heart failure patients with reduced ejection fraction, AF on admission was not associated with poor long-term clinical outcomes among HFpEF patients. Several in-hospital outcomes were better in patients with AF than in those without. Acknowledgement/Funding None

scholarly journals Relationships between maintenance of sinus rhythm and clinical outcomes in patients with heart failure with preserved ejection fraction and atrial fibrillation

2019 ◽  
Vol 74 (3) ◽  
pp. 235-244 ◽  
Author(s):  
Tomoko Machino-Ohtsuka ◽  
Yoshihiro Seo ◽  
Tomoko Ishizu ◽  
Masayoshi Yamamoto ◽  
Yoshie Hamada-Harimura ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Ejection Fraction ◽  
Sinus Rhythm ◽  
Clinical Outcomes ◽  
Preserved Ejection Fraction ◽  
Patients With Heart Failure
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