scholarly journals Renal Anastomosing Hemangioma Simulating Angiosarcoma as a Second Primary in a Patient with Breast Cancer

2021 ◽  
Vol 11 (12) ◽  
pp. 466-473
Author(s):  
Daniel Fernando Méndez López ◽  
Jhonatan Gómez Domínguez ◽  
Jorge Antonio Rojas González ◽  
Marco Antonio Ortiz Jiménez ◽  
Omar Santos Moreno
2016 ◽  

Aims and Objectives: To report a series of cases with breast and ovarian carcinomas either in same patient or in a family and identifying the importance of BRCA 1,2 genetic testing in such individuals. Materials and Methods: The medical records of breast and ovarian cancer patients operated over past 3 years at a single institute were reviewed retrospectively and their clinical profile, family history, final pathological reports and follow up data was collected. Results: 8 patients were found to have breast and ovarian malignancies, out of which 3 had synchronous breast and ovarian cancers, 4 had metachronous and 1 patient with ovarian cancer had history of breast cancer in family. Median age of presentation to the hospital was 47 years and median time interval in metachronous disease patients was 5.5 years. Conclusion: About 5% of people who have breast cancer and about 10% of women who have ovarian cancer have HBOC, caused by germline mutation in BRCA1, 2 gene. These individuals have increased risk of developing breast cancer at younger age, TNBC, or developing a second primary in breast or ovary plus an overall risk of breast/ovarian/prostate/pancreatic malignancies in other family members due to inheritable mutation. Identification of BRCA mutation in such individuals can help family members to undergo genetic counseling and follow different screening and prevention guidelines from general population thus reducing the cancer risks.


2020 ◽  
pp. 1-10
Author(s):  
Alexandre M. C. Santos ◽  
Andreas Kotsanis ◽  
Lisa Cunningham ◽  
Scott N. Penfold

2015 ◽  
Vol 151 (3) ◽  
pp. 653-660 ◽  
Author(s):  
Tehillah S. Menes ◽  
Mary Beth Terry ◽  
David Goldgar ◽  
Irene L. Andrulis ◽  
Julia A. Knight ◽  
...  

2021 ◽  
Vol 14 (4) ◽  
pp. e241361
Author(s):  
Jamin Kweku Addae ◽  
Thomas Genuit ◽  
Joseph Colletta ◽  
Kathy Schilling

Accessory breast tissue (ABT) is found in approximately 2%–6% of the female population and are subject to most of the physiological and pathological changes that occur in pectoral breast. Primary breast cancer occurring in ABT is a rare occurrence and a second primary breast cancer occurring in an accessory breast has never been reported. We report the case of a 60-year-old woman with a history of mastectomy for left breast cancer 5 years prior to presentation, who presented with an enlarging right axilla mass found to be a second primary breast cancer in an accessory tissue on biopsy. Many physicians are unfamiliar with the clinical presentation of accessory breast cancer due to the rarity of the condition and this ultimately results in delayed diagnosis and advanced disease at presentation. It is therefore prudent that physicians have a high index of suspicion when patients present with axillary masses.


BMJ ◽  
1988 ◽  
Vol 296 (6639) ◽  
pp. 1755-1756 ◽  
Author(s):  
O Eremin

2018 ◽  
Vol 8 (1) ◽  
pp. 400-407 ◽  
Author(s):  
Guoqiao Zheng ◽  
Akseli Hemminki ◽  
Asta Försti ◽  
Jan Sundquist ◽  
Kristina Sundquist ◽  
...  

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