231. Synchronous and metachronous bilateral breast cancer – A comparison of clinical, histopathological features of the first and second primary breast cancer and BRCA 1 and 2 mutations

2003 ◽  
Vol 8 ◽  
pp. S298-S299
Author(s):  
E. Nowicka ◽  
J. Rogozińska ◽  
E. Grzybowska ◽  
K. Behrendt ◽  
A. Mucha-Małecka ◽  
...  
2015 ◽  
Vol 151 (3) ◽  
pp. 653-660 ◽  
Author(s):  
Tehillah S. Menes ◽  
Mary Beth Terry ◽  
David Goldgar ◽  
Irene L. Andrulis ◽  
Julia A. Knight ◽  
...  

2021 ◽  
Vol 14 (4) ◽  
pp. e241361
Author(s):  
Jamin Kweku Addae ◽  
Thomas Genuit ◽  
Joseph Colletta ◽  
Kathy Schilling

Accessory breast tissue (ABT) is found in approximately 2%–6% of the female population and are subject to most of the physiological and pathological changes that occur in pectoral breast. Primary breast cancer occurring in ABT is a rare occurrence and a second primary breast cancer occurring in an accessory breast has never been reported. We report the case of a 60-year-old woman with a history of mastectomy for left breast cancer 5 years prior to presentation, who presented with an enlarging right axilla mass found to be a second primary breast cancer in an accessory tissue on biopsy. Many physicians are unfamiliar with the clinical presentation of accessory breast cancer due to the rarity of the condition and this ultimately results in delayed diagnosis and advanced disease at presentation. It is therefore prudent that physicians have a high index of suspicion when patients present with axillary masses.


BMJ ◽  
1988 ◽  
Vol 296 (6639) ◽  
pp. 1755-1756 ◽  
Author(s):  
O Eremin

2011 ◽  
Vol 131 (2) ◽  
pp. 571-580 ◽  
Author(s):  
Jennifer D. Brooks ◽  
◽  
Esther M. John ◽  
Lene Mellemkjær ◽  
Anne S. Reiner ◽  
...  

2019 ◽  
Vol 19 (3) ◽  
pp. 305-308
Author(s):  
Rajanigandha Tudu ◽  
Anup Kumar ◽  
Rashmi Singh ◽  
Payal Raina

AbstractBackground:Breast cancer is the most common cancer among females worldwide. Increasing breast cancer incidence rates, improved diagnosis and management modalities and growing life expectancy have resulted in increasing numbers of women at risk of developing contralateral primary breast cancer. Bilateral breast cancer can occur synchronously or metachronously.Material and methods:This study reports three cases of bilateral breast cancer patients treated at our oncology department between March 2018 and March 2019. The features of presentation, investigation, diagnosis and follow-up care are the highlights of this study.Results:Bilateral breast cancer was noted in three patients among the study population in the age group of 35 –55 years. Two of these patients had metachronous bilateral breast cancer, and one patient developed cancer in the second breast during the course of management. The second breast cancers differed histologically from primary breast cancer.Conclusion:Poor awareness on breast cancer care and the lack of national screening guidelines and programmes, and poor infrastructure, all contribute to late presentation and difficult breast cancer management. Proper history, clinical examination and imaging of opposite breast should be done to ensure adequate and timely management of bilateral breast cancer.


2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19593-e19593
Author(s):  
Harveshp D. Mogal ◽  
Emad S. Allam ◽  
Julie A. Margenthaler ◽  
Ling Chen ◽  
Katherine S. Virgo ◽  
...  

e19593 Background: Breast carcinoma is the most common cancer among American women except for skin cancer. Over 200,000 patients are diagnosed with breast cancer annually in the U.S. Most receive curative-intent treatment. About 2.5 million women with a history of breast cancer are now alive and eligible for surveillance. ASCO has published evidence-based guidelines for surveillance after primary breast cancer treatment but dramatic variation in the actual practice patterns of ASCO clinicians has been shown. We sought to evaluate potential factors that motivate expert clinicians as they design their own surveillance strategies. Methods: A custom-designed survey instrument with 11 questions about putative motivating factors was e-mailed to the 3,245 ASCO members who had indicated that breast cancer was a major focus of their clinical practice. Responses were submitted on a 10-level Likert-type scale. The percentage of responses for each point on the scale for each of the potential motivating factors was tabulated. We ranked the factors in accordance with the percentage responses on the scale. Results: 1,013 responses (31%) were submitted; 734 (73%) were evaluable. “Potential detection of a second primary breast cancer” was the strongest motivating factor (53% with a score of "strongly agree"). Conclusions: We believe this is the first empirical evidence about factors that may motivate expert clinicians in selecting surveillance strategies. Understanding these factors may be useful in devising methods to decrease the present variation in these strategies. [Table: see text]


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