scholarly journals Inhibition of subcutaneously implanted human pituitary tumor cells in nude mice by LRIG1

2016 ◽  
Vol 15 (2) ◽  
Author(s):  
X. Wang ◽  
X.J. He ◽  
H.Q. Xu ◽  
Z.W. Chen ◽  
H.H. Fan
Keyword(s):  
Tumor Cells ◽  
Nude Mice ◽  
Pituitary Tumor ◽  
Human Pituitary ◽  
Human Pituitary Tumor

Pertussis toxin inhibits somatostatin-induced K+ conductance in human pituitary tumor cells

1987 ◽  
Vol 253 (1) ◽  
pp. E28-E32 ◽  
Author(s):  
N. Yamashita ◽  
I. Kojima ◽  
N. Shibuya ◽  
E. Ogata
Keyword(s):  
Tumor Cells ◽  
Pertussis Toxin ◽  
Pituitary Tumor ◽  
Action Potentials ◽  
Human Pituitary ◽  
K Current ◽  
Spontaneous Action ◽  
Spontaneous Action Potentials ◽  
Crude Membrane Fraction ◽  
Human Pituitary Tumor

The effect of pertussis toxin on somatostatin-induced K+ current was examined in dissociated human pituitary tumor cells obtained from two acromegalic patients. Somatostatin-induced hyperpolarization or K+ current was observed in 20 of 23 cells in adenoma 1 and 10 of 11 cells in adenoma 2. After treatment with pertussis toxin for 24 h, these responses were completely suppressed (0/14 in adenoma 1, 0/10 in adenoma 2). Spontaneous action potentials, K+, Na+, and Ca2+ currents were well preserved after pertussis toxin treatment. When crude membrane fraction was incubated with [32P]NAD, a 41K protein was ADP-ribosylated by pertussis toxin. Hormone release was inhibited by somatostatin and this inhibition was blocked by pertussis toxin treatment.

scholarly journals Expression of Interleukin-6 and Its Effects on Growth of HP75 Human Pituitary Tumor Cells

2003 ◽  
Vol 88 (10) ◽  
pp. 4938-4944 ◽  
Author(s):  
S. A. Borg ◽  
K. E. Kerry ◽  
L. Baxter ◽  
J. A. Royds ◽  
T. H. Jones
Keyword(s):  
Tumor Cells ◽  
Interleukin 6 ◽  
Pituitary Tumor ◽  
Human Pituitary ◽  
Human Pituitary Tumor

scholarly journals Internalization of the radioiodinated somatostatin analog [125I-Tyr3]octreotide by mouse and human pituitary tumor cells: increase by unlabeled octreotide.

Endocrinology ◽  
1995 ◽  
Vol 136 (9) ◽  
pp. 3698-3706 ◽  
Author(s):  
L J Hofland ◽  
P M van Koetsveld ◽  
M Waaijers ◽  
J Zuyderwijk ◽  
W A Breeman ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Pituitary Tumor ◽  
Somatostatin Analog ◽  
Human Pituitary ◽  
Human Pituitary Tumor

Effects of TGFβ1 on gene expression in the HP75 human pituitary tumor cell line identified by gene expression profiling

Endocrine ◽  
2008 ◽  
Vol 33 (1) ◽  
pp. 62-76 ◽  
Author(s):  
Katharina H. Ruebel ◽  
Alexey A. Leontovich ◽  
Yoshinori Tanizaki ◽  
Long Jin ◽  
Gail A. Stilling ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tumor Cell ◽  
Gene Expression Profiling ◽  
Cell Line ◽  
Expression Profiling ◽  
Pituitary Tumor ◽  
Tumor Cell Line ◽  
Human Pituitary ◽  
Human Pituitary Tumor ◽  
Pituitary Tumor Cell
Sign in / Sign up

Export Citation Format

Share Document