scholarly journals Diabetes and cardiac autonomic neuropathy: Clinical manifestations, cardiovascular consequences, diagnosis and treatment

2015 ◽  
Vol 6 (1) ◽  
pp. 80 ◽  
Author(s):  
Akif Serhat Balcıoğlu
Keyword(s):  
Autonomic Neuropathy ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Cardiac Autonomic Neuropathy

scholarly journals Autonomic neuropathy in diabetes mellitus: Clinical manifestations, diagnosis and treatment

2011 ◽  
Vol 0 (2) ◽  
pp. 25
Author(s):  
Aleksey Nikolaevich Barinov ◽  
M V Novosadova ◽  
Aleksey Nikolayevich Barinov ◽  
M V Novosadova
Keyword(s):  
Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment

scholarly journals Cardiac autonomic neuropathy in diabetic patients

2019 ◽  
pp. 52-56
Author(s):  
A. A. Belyaev ◽  
O. V. Kotova ◽  
E. S. Akarachkova
Keyword(s):  
Autonomic Neuropathy ◽  
Clinical Manifestations ◽  
Cardiac Autonomic Neuropathy ◽  
Diabetic Patients ◽  
Autoimmune Reaction ◽  
Obstructive Sleep ◽  
Key Points ◽  
Patients With Diabetes ◽  
The Impact

Cardiac autonomic neuropathy (CAN) is a common and insufficiently diagnosed complication of diabetes mellitus. This is usually due to the fact that the disease runs asymptomatically until the very late stages. The impact of CAN on patients with diabetes can be devastating, because CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease. CAN prevalence: 17-66% in patients with type 1 diabetes and 31–73% in patients with type 2 diabetes. Hyperglycemia, autoimmune reaction, genetic factors, obstructive sleep apnea, and inflammation are the key points in the pathogenesis of neuropathies in diabetes, in particular, CAN. Clinical manifestations of CAN and risk factors of CAN development in patients with diabetes are considered. Early diagnosis of CAN is of vital importance for the success of therapy, as there is an assumption that denervation of cardiovascular system may be reversible if diagnosed soon after its beginning. Antioxidant, vasoactive and vitamin therapy is used in the treatment of CAN. Emphasis is placed on the use of the injection form of Neuromultivitis.

Mechanism Underlying the Formation of a Cluster of Metabolic Syndrome

2020 ◽  
Vol 20 (4) ◽  
pp. 564-569 ◽  
Author(s):  
Svetlana Igorevna Kseneva ◽  
Elena Valentinovna Borodulina ◽  
Vladimir Vasilievich Udut ◽  
Vladimir Petrovich Fisenko
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Autonomic Neuropathy ◽  
Autonomic Dysfunction ◽  
Reflux Disease ◽  
Prostate Gland ◽  
Clinical Manifestations ◽  
Cardiac Autonomic Neuropathy

Background: The concept of metabolic syndrome (MetS) as a cluster of risk factors of type 2 diabetes and cardiovascular diseases has undergone some evolutionary transformations over the past years. Integrating the autonomic dysfunction into the pathogenesis of MetS creates the possibility of including a range of nosologies affecting treatment and clinical manifestations of pathologies belonging to MetS into the MetS cluster. The purpose of this work is to determine the involvement of autonomic dysfunction in the pathogenesis of associated pathological conditions in patients and MetS. Methods: A cross-sectional study was conducted. The sample consisted of 158 patients with metabolic syndrome. The patients underwent a physical examination, including BMI; a blood chemistry test with the determination of the hormonal status (insulin, testosterone, dihydrotestosterone); a 24-hour monitoring of blood pressure (BP); an assessment of heart rate variability; studies showing the presence of gastric reflux (рН-measurement) or its damaging impact (endoscopy); men were tested with the IPSSQOL questionnaire and underwent transrectal ultrasound of the prostate and ultrasound of the bladder. Results: It is revealed that because of MetS, the occurrence of cardiac autonomic neuropathy reaches 37.5%. Some features of gastroesophageal reflux disease in patients with MetS are shown. Regurgitation prevails in the structure of complaints. In case of fibrogastroduodenoscopy, an endoscopynegative form of the disease occurs in 38%. According to the data of daily pH-measurement, when DeMeester score is high, in the supine position, 25% of the time accounts for alkaline reflux (рН > 7). It is found out that young men experience the enlargement of prostate volume and size; according to the IPSS questionnaire, the scores correspond to the initial manifestations of hyperplastic diseases of the prostate gland due to insulin resistance and normal level of androgens. Conclusions: The paper demonstrates that the autonomic dysfunction of the nervous system (on a par with insulin resistance) is the main link in the development of MetS. This provides the basis for including the mentioned states – cardiac autonomic neuropathy, lower urinary tract symptoms, and gastroesophageal reflux disease – into the MetS cluster..

scholarly journals Cardiac diabetic autonomic neuropathy

2020 ◽  
pp. 94-102
Author(s):  
L. T. Akhmedzhanova ◽  
T. A. Belyakova ◽  
Yu. A. Podkovko ◽  
Yu. M. Shor
Keyword(s):  
Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Clinical Case ◽  
Clinical Symptoms ◽  
Early Stage ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Diabetic Polyneuropathy ◽  
Neurological Complications ◽  
Cardiac Autonomic Neuropathy

The prevalence of diabetes mellitus (DM) is steadily increasing and represents a significant public health problem. At the same time, the incidence of neurological complications of diabetes mellitus, especially diabetic polyneuropathy, is increasing. Cardiac autonomic neuropathy, a form of diabetic polyneuropathy, is the most serious complication of diabetes mellitus, as it is an independent risk factor for cardiovascular complications in patients with diabetes mellitus and is associated with increased mortality. Due to prolonged asymptomatic flow, cardiac autonomic neuropathy is often diagnosed at a late stage when treatment is not very effective. A targeted search for clinical symptoms of the disease and especially the conduct of cardiovascular tests, which make it possible to diagnose the pathology at an early stage, is essential. Clinical manifestations of cardiac autonomic neuropathy, methods of clinical and instrumental diagnostics, treatment of the disease are considered in detail in the article. The clinical case of a patient with type 2 diabetes mellitus and cardiac autonomic neuropathy, represented by orthostatic hypotension, which is the most disabling symptom, is considered. On the example of a clinical case the medicamentous and non-medicamentous approaches to treatment are discussed, as well as the role of antioxidant therapy, in particular, the preparation of alpha-lipoic acid («Berlithion») in the treatment of cardiac autonomic neuropathy.

548-P: Early Liver Dysfunction Predicts Cardiac Autonomic Neuropathy in Adolescents with Type 1 Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 548-P
Author(s):  
VALLIMAYIL VELAYUTHAM ◽  
PAUL Z. BENITEZ-AGUIRRE ◽  
MARIA E. CRAIG ◽  
JANINE CUSUMANO ◽  
GERALD LIEW ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Autonomic Neuropathy ◽  
Liver Dysfunction ◽  
Cardiac Autonomic Neuropathy

Clinical manifestations, diagnosis and treatment of HIV infection of stage 4 (severely symptomatic stage) in the practice of a health professional

2020 ◽  
pp. 27-34
Author(s):  
A. Nikitina ◽  
A. Rusanova ◽  
A. Zhilenkova
Keyword(s):  
Hiv Infection ◽  
Health Professional ◽  
Clinical Picture ◽  
Clinical Manifestations ◽  
Significant Problem ◽  
Diagnosis And Treatment ◽  
Modern World ◽  
Infected People ◽  
Stage 4 ◽  
Future Practice

HIV infection is a significant problem in the modern world, because there are more and more infected people every year. This article will consider: the clinical picture, diagnosis and treatment of this disease in different countries. Based on these data, the following conclusions will be made to help doctors in their future practice correctly approach the diagnosis and treatment of patients with this disease.

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