Data Screening Methods – Application to Differential Diagnosis in Pancreatic Pathology from Radiological Signs

1978 ◽  
Vol 17 (01) ◽  
pp. 36-40 ◽  
Author(s):  
J.-P. Durbec ◽  
Jaqueline Cornée ◽  
P. Berthezene
Keyword(s):  
Differential Diagnosis ◽  
Mutual Information ◽  
Data Processing ◽  
Screening Methods ◽  
Automatic Data ◽  
Chronic Calcifying Pancreatitis ◽  
Number Of Patients ◽  
Calcifying Pancreatitis ◽  
Pancreatic Pathology ◽  
Data Screening

The practice of systematic examinations in hospitals and the increasing development of automatic data processing permits the storing of a great deal of information about a large number of patients belonging to different diagnosis groups.To predict or to characterize these diagnosis groups some descriptors are particularly useful, others carry no information. Data screening based on the properties of mutual information and on the log cross products ratios in contingency tables is developed. The most useful descriptors are selected. For each one the characterized groups are specified.This approach has been performed on a set of binary (presence—absence) radiological variables. Four diagnoses groups are concerned: cancer of pancreas, chronic calcifying pancreatitis, non-calcifying pancreatitis and probable pancreatitis. Only twenty of the three hundred and forty initial radiological variables are selected. The presence of each corresponding sign is associated with one or more diagnosis groups.

scholarly journals Verificatie van data-integriteit, validiteit, en voorwaarden

2019 ◽  
Author(s):  
Gjalt - Jorn Ygram Peters ◽  
Ron Jonathan Pat-El
Keyword(s):  
Data Integrity ◽  
Practical Guide ◽  
Dutch Language ◽  
Data Screening

This is a Dutch-language practical guide to data screening, discussing how to plan for and subsequently check for data integrity, validity, and assumptions of analyses.

scholarly journals Validation of the Aura High Resolution Dynamics Limb Sounder geopotential heights

2014 ◽  
Vol 7 (2) ◽  
pp. 1001-1025
Author(s):  
L. L. Smith ◽  
J. C. Gille
Keyword(s):  
High Resolution ◽  
System Model ◽  
Weather Forecasts ◽  
Atmospheric Research ◽  
Earth Observing System ◽  
Medium Range ◽  
High Bias ◽  
Environmental Prediction ◽  
The Tropics ◽  
Data Screening

Abstract. Global satellite observations from the EOS Aura spacecraft's High Resolution Dynamics Limb Sounder (HIRDLS) of temperature and geopotential height (GPH) are discussed. The accuracy, resolution and precision of the HIRDLS version 7 algorithms are assessed and data screening recommendations are made. Comparisons with GPH from observations, reanalyses and models including European Center for Medium-Range Weather Forecasts Interim Reanalysis (ERA-Interim), National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR) Reanalysis, Goddard Earth Observing System Model (GEOS) version 5, and EOS Aura Microwave Limb Sounder (MLS) illustrate the HIRDLS GPH have a precision ranging from 2 m to 30 m and an accuracy of ±100 m. Comparisons indicate HIRDLS GPH may have a slight low bias in the tropics and a slight high bias at high latitudes. Geostrophic winds computed with HIRDLS GPH qualitatively agree with winds from other data sources including ERA-Interim, NCEP and GEOS-5.

Screening for hypophosphatasia: does biochemistry lead the way?

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Corinna Melanie Held ◽  
Anic Guebelin ◽  
Andreas Krebs ◽  
Jörn Oliver Sass ◽  
Michael Wurm ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Enzyme Replacement Therapy ◽  
Pediatric Population ◽  
Laboratory Data ◽  
Diagnostic Algorithm ◽  
Inorganic Pyrophosphate ◽  
Enzyme Replacement ◽  
Underlying Diseases ◽  
Data Screening ◽  
Serum And Urine

Abstract Objectives Patients with childhood hypophosphatasia (HPP) often have unspecific symptoms. It was our aim to identify patients with mild forms of HPP by laboratory data screening for decreased alkaline phosphatase (AP) within a pediatric population. Methods We conducted a retrospective hospital-based data screening for AP activity below the following limits: Girls: ≤12 years: <125 U/L; >12 years: <50 U/L Boys: ≤14 years: <125 U/L; >14 years: <70 U/L. Screening positive patients with otherwise unexplained hypophosphatasemia were invited for further diagnostics: Re-test of AP activity, pyridoxal 5′-phosphate (PLP) in hemolyzed whole blood, phosphoethanolamine (PEA) in serum and urine, and inorganic pyrophosphate in urine. Sequencing of the ALPL gene was performed in patients with clinical and/or laboratory abnormalities suspicious for HPP. Results We assessed a total of 14,913 samples of 6,731 patients and identified 393 screening-positive patients. The majority of patients were excluded due to known underlying diseases causing AP depression. Of the 30 patients who participated in the study, three had a decrease in AP activity in combination with an increase in PLP and PEA. A heterozygous ALPL mutation was detected in each of them: One patient with a short stature was diagnosed with childhood-HPP and started with enzyme replacement therapy. The remaining two are considered as mutation carriers without osseous manifestation of the disease. Conclusions A diagnostic algorithm based on decreased AP is able to identify patients with ALPL mutation after exclusion of the differential diagnoses of hypophosphatasemia and with additional evidence of increased AP substrates.

Sickness Absence Culture: A Scoping Review

2021 ◽  
Author(s):  
Erlend Pukstad ◽  
Sofie Lorentzen ◽  
Torstein Låg ◽  
Arnstein Mykletun
Keyword(s):  
Sickness Absence ◽  
Scoping Review ◽  
Future Research ◽  
Original Research ◽  
Human Sciences ◽  
Science Base ◽  
Scoping Reviews ◽  
Group Members ◽  
Data Screening ◽  
Broad Overview

Abstract Background: Several studies show that the absence behavior of co-workers’ influence the absence rates of individual group members so that an employee is more likely to be absent when co-workers are often absent. To our knowledge, there are no systematic scoping reviews or other reviews on the concept of sickness absence culture. The objective of this review is to identify and map existing literature on sickness absence culture. We will also investigate what methods and designs are used.Methods: We will be conducting a systematic scoping review with the aim of getting a broad overview of the preexisting literature. This scoping review will consider any publication on sickness absence culture in the field of human sciences, including also reviews, original research, and opinion pieces. The review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and a populated PRISMA-P checklist (Additional file 1). Two reviewers will independently screen all abstracts for inclusion. We will search the electronic databases: MEDLINE, Embase, PsycINFO, Clarivate Web of Science, BASE and CINAHL. We will use Covidence for data screening and extraction. The final stage will include a narrative synthesis of the data.Discussion: The results of this scoping review will contribute to identifying and mapping the existing literature on sickness absence culture, which could facilitate future research on the topic. Systematic review registration: Not registered in publicly accessible registry.

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