Environmental toxicology and health risk assessment in the United States: economic and policy issues

Author(s):  
Mark Dickie
2014 ◽  
Vol 71 ◽  
pp. 42-50 ◽  
Author(s):  
Brooke E. Tvermoes ◽  
Amber M. Banducci ◽  
Kathryn D. Devlin ◽  
Brent D. Kerger ◽  
Mathew M. Abramson ◽  
...  

Author(s):  
A.I. Yaradua ◽  
A. J. Alhassan ◽  
A. Nasir ◽  
S. S. Matazu ◽  
A. Usman ◽  
...  

Vegetable fields in Katsina State are increasingly being loaded with heavy metals through various pollution sources such as agricultural activities mining and traffic. Onion bulb samples from the three senatorial zones that constitute to make up Katsina state in the North West of Nigeria were collected and the concentrations of seven heavy metals (Pb, Cd, Cr, Fe, Zn, Mn and Ni) in all the samples were determined by atomic absorption spectrometry. The health risk assessment methods developed by the United States Environmental Protection Agency (US EPA) were employed to explore the potential health hazards of heavy metals in the samples on the children and adult population. The highest mean concentration (mg/kg) was observed for Fe, followed by Pb, Zn and Mn. While Cd has the lowest concentration with the heavy metals Cr and Ni being below detection level (BDL). Overall hazard index (Hi) for the heavy metals were within the safety limit. The overall cancer risk to the adults based on pseudo-total metal concentrations exceeded the target value, mainly contributed by Pb.  Mn and Zn were the primary heavy metals posing non-cancer risks while Pb caused the greatest cancer risk. It was concluded that consumption of the onion samples from Katsina State may contribute to the population cancer burden.


2021 ◽  
Vol 25 (1) ◽  
pp. 71-77
Author(s):  
Nguyen Thanh Giao ◽  
Phan Kim Anh ◽  
Huynh Thi Hong Nhien

The study was conducted to assess the health risks of workers due to exposure to toxic gases including benzene, toluene, ethylbenzene, m, p-xylene, o-xylene, formaldehyde and acetaldehyde at gasoline retail stations. In this study, data on the  concentrations of the toxic gases were collected from the previously published studies in the qualified scientific journals. The health risk assessment was followed by the process of the United States Environment Protection Agency (U.S. EPA). The results show that the concentrations of benzene, toluene, ethylbenzene, m, p-xylene, o-xylene, formaldehyde, and acetaldehyde were in the range of 12.40 - 357.5, 12.47 - 574.17, 2.05 - 156.5, 4.57 - 218, 2.36 - 77.04, 3.64 - 153.93 and 1.27- 27.83 µg/m3 , respectively. Life time cancer risk for gasoline station workers due to exposure to benzene, ethylbenzene, formaldehyde, and acetaldehyde was calculated in the ranges of 2.13x10-5 - 6.14x10-4 , 4.96x10-7 - 3.79x10-5 , 4.81x10-6 - 2.03x10-4 , and 7.99x10-7 - 1.75x10-5 , respectively. For non-carcinogenic  compounds, the hazard index due to benzene, toluene, m, p-xylene, o-xylene were respectively in the range of 0.13 - 3.81, 7.97x10-4 -  0.04, 0.01 - 0.70 and 0.01 - 0.25. The findings revealed that there is high risk of cancer and non-cancer for the workers working at the gasolines stations if they are not taking good preventive measures. The calculation showed that the limit levels of benzene, toluene, ethylbenzene, xylene, formaldehyde and acetaldehyde should be reduced to 5.82x10-4 , 15.64, 4.13x10- 3 , 0.31, 7.57x10-4 and 1.59x10-3 mg/m3 , respectively to meet the safety levels for the workers at the gasoline stations. Keywords: benzene, toluene, ethylbenzene, xylene, formaldehyde, acetaldehyde, life-time cancer risk, health


2016 ◽  
Vol 8 (1) ◽  
pp. 178 ◽  
Author(s):  
John Kanayochukwu Nduka ◽  
Isaac Omoche Odiba ◽  
Eruemrejovwo Inspector Aghoghome ◽  
Ngozi Lilian Umedum ◽  
Maduabuchi Joseph Nwosu

Forty two different cosmetic samples consisting of 16 facial cosmetics, 6 soaps, 1 shower gel, 12 emulsions, 2 underarm cosmetics, 3 nail cosmetics and 2 perfumes were purchased from department stores and cosmetic shops within Onitsha Main Market and Eke-Awka in Anambra, Nigeria. Seven of these cosmetic (16.67%) were locally manufactured in Nigeria while thirty five (83.33%) were imported into Nigeria. The cosmetics were ashed before digestion and filtration. The filtrates were assayed for mercury and arsenic with AAS SearchTech AA320N. Hydroquinone presence was identified by chromatographic test while steroids, nitrite and N-nitrosamines were identified by colour test and together were assayed by UV-spectrophotometer (Spectrulab 21). The health risk assessment methods developed by the United States Environmental Protection Agency (US EPA) were employed to explore the potential human health risk of Mercury and Arsenic in cosmeticsamples. Results showed that two (2)  of the cosmetic samples contained mercury ( 0.003 + 0.000mg/kg and 0.07 + 0.00mg/kg)  while three cosmetic samples contained arsenic (0.002 + 0.000, 0.002+0.000 and 0.005 +0.000 mg/kg). Hydroquinone concentration ranged from 1.14 + 0.00 – 1.83 + 0.03 mg/kg (1.14E-02 – 1.83E-02 %).Steroid was found in only two samples with concentration of 16.70 + 0.74 mg/kg and 17.63 + 0.74 while N-nitrosamines and nitrite occurred in nine and eleven samples in the range of 4.66 + 0.09 – 43.52 + 0.47 and 0.87 + 0.02 – 13.42 + 2.90 respectively. The total cancer and non-cancer risk results indicated that although the chances of cancer risk and non-cancer risk resulting from the use of these cosmetic products were unlikely, build up of these heavy metals overtime on continuous usage could be detrimental.


Author(s):  
Haseeb Tufail Moryani ◽  
Shuqiong Kong ◽  
Jiangkun Du ◽  
Jianguo Bao

The aim of this study is to identify and investigate levels of toxic heavy metals in PM2.5 fractioned road dust to better understand the associated inhalation risk and potential health impacts. To achieve this aim, concentrations of seven traffic generated heavy metals (Cu, Pb, Zn, Cd, Ni, Sb, and Cr) were determined in the PM2.5 fraction of road dust samples from four different locations (offices, residential, hospital, and school) in two cities (Karachi and Shikarpur) of Pakistan using ICP-MS. The average concentration values of heavy metals in Karachi were as follows: 332.9 mg/kg Cu, 426.6 mg/kg Pb, 4254.4 mg/kg Zn, 62.3 mg/kg Cd, 389.7 mg/kg Ni, 70.4 mg/kg Sb, 148.1 mg/kg Cr, whereas the average concentration values of heavy metals in Shikarpur were 245.8 mg/kg Cu, 538.4 mg/kg Pb, 8351.0 mg/kg Zn, 57.6 mg/kg Cd, 131.7 mg/kg Ni, 314.5 mg/kg Sb, 346.6 mg/kg Cr. The pollution level was assessed through two pollution indices enrichment factor (EF) and geoaccumulation index (Igeo). These indices showed moderate to extreme level pollution in studied areas of both cities. The health risk assessment through inhalation contact was conducted according to the United States Environmental Protection Agency’s (USEPA) model for children and adults. Both non-cancerous and cancerous risks were characterised in the road dust samples for each location. As yet, there is not a single study on the concentrations of heavy metals in PM2.5 fractions of road dust in Karachi and Shikarpur, findings of this research will facilitate researchers for further investigations in current field.


Background: In the Azna-Aligudarz plain, the drinking water is mainly supplied from groundwater. Therefore, it is necessary to estimate the concentration of nitrate and nitrite and determine the groundwater vulnerability potential and related risks in the plain to guarantee the health of consumers. Materials and Methods: The vulnerability potential of the studied plain to pollutants was investigated by the drastic method. To estimate the concentration of nitrate and nitrite, 25 water wells in the study area were sampled within 2018-2019 and analyzed by standard method. Human health risk related to groundwater in the study area was assessed using the USEPA (the United States Environmental Protection Agency) index. Results: The results of the DRASTIC method demonstrated that 45% and 65% of the region has a high (southern part of the plain) and a medium vulnerability potential (northern part of the plain), respectively. According to the obtained results, nitrate in Chaqataram and Ashrafabad villages with 56 and 65 mg/liter, respectively, and nitrite in groundwater of Chamzaman, Aliabad, and Darreh Bagh villages with 3.5, 3.3, and 3.4 mg/liter, was higher than the standard of World Health Organization. According to the health risk assessment results, 83%, 8%, and 4% of children, women, and men are prone to health threats due to nitrate concentration (HQ>1). The accuracy of the vulnerability results was confirmed by calibrating the results of the health risk assessment and the results of the nitrate map. Conclusion: As e evidenced by the obtained results, improper use of nitrate chemical fertilizers and unsafe disposal of human wastewater (urban and rural) is the main cause of increased nitrate and nitrite concentrations in agricultural lands. Based on the results of the present study, the use of contaminated drinking wells is not recommended and continuous monitoring of drinking wells in the study area is essential to protect the health of consumers, especially children.


2021 ◽  
Vol 100 (12) ◽  
pp. 1344-1349
Author(s):  
Michael Brody ◽  
Simon L. Avaliani

Environmental health risk assessment has a long history in both the United States and Russia. Risk assessment methods have arisen and developed to protect against the dangers of the forced use of tens of thousands of chemicals in the modern world. Because chemicals play such an important role, it is impossible to ban their use altogether, and the task of their safe use becomes more and more critical. With the solution of this problem, the creation of modern environmental legislation began, based on an assessment of the hazard or potential hazard associated with the impact of these substances on humans. Risk assessment has become the scientific basis for calculating exposure limits for many chemicals that pollute the environment. Since compliance with environmental legislation is costly to industry, methods have been developed. They are being improved on to quantify the burden of proof and the appropriateness of environmental quality regulation. Environmental Health Risk Assessment was first developed by the United States Environmental Protection Agency (US EPA). Russia has accumulated a great deal of practical experience in assessing environmental risks and developing appropriate methodological recommendations. Thus, the basis was created for long-term cooperation between the two countries. This article summarizes the history of such collaboration, including a joint project to disseminate practical risk assessment in Ukraine.


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