scholarly journals Effect of a Laboratory Result Pager on Provider Behavior in a Neonatal Intensive Care Unit

2011 ◽  
Vol 02 (03) ◽  
pp. 384-394 ◽  
Author(s):  
TA. Stavroudis ◽  
RE. Miller ◽  
HP. Lehmann ◽  
CU. Lehmann ◽  
L. Samal
Keyword(s):  
Intensive Care Unit ◽  
Logistic Regression ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
P Value ◽  
Laboratory Result ◽  
Abnormal Laboratory ◽  
Provider Behavior ◽  
Implementation Period

Summary Background: A computerized laboratory result paging system (LRPS) that alerts providers about abnormal results (“push”) may improve upon active laboratory result review (“pull”). However, implementing such a system in the intensive care setting may be hindered by low signal-to-noise ratio, which may lead to alert fatigue. Objective: To evaluate the impact of an LRPS in a Neonatal Intensive Care Unit. Methods: Utilizing paper chart review, we tallied provider orders following an abnormal laboratory result before and after implementation of an LRPS. Orders were compared with a predefined set of appropriate orders for such an abnormal result. The likelihood of a provider response in the post-implementation period as compared to the pre-implementation period was analyzed using logistic regression. The provider responses were analyzed using logistic regression to control for potential confounders. Results: The likelihood of a provider response to an abnormal laboratory result did not change significantly after implementation of an LRPS. (Odds Ratio 0.90, 95% CI 0.63–1.30, p-value 0.58) However, when providers did respond to an alert, the type of response was different. The proportion of repeat laboratory tests increased. (26/378 vs. 7/278, p-value = 0.02) Conclusion: Although the laboratory result pager altered healthcare provider behavior in the Neonatal Intensive Care Unit, it did not increase the overall likelihood of provider response.

scholarly journals 1412. The utility of respiratory viral panel testing for nosocomial fever in the neonatal intensive care unit

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S713-S713
Author(s):  
Carlo Fopiano Palacios ◽  
Eric Lemmon ◽  
James Campbell
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Linear Regression ◽  
Length Of Stay ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
P Value ◽  
Fisher Exact Test ◽  
The Mean ◽  
Pcr Test

Abstract Background Patients in the neonatal intensive care unit (NICU) often develop fevers during their inpatient stay. Many neonates are empirically started on antibiotics due to their fragile clinical status. We sought to evaluate whether the respiratory viral panel (RVP) PCR test is associated with use of antibiotics in patients who develop a fever in the NICU. Methods We conducted a retrospective chart review on patients admitted to the Level 4 NICU of the University of Maryland Medical Center from November 2015 to June 2018. We included all neonates who developed a fever 48 hours into their admission. We collected demographic information and data on length of stay, fever work-up and diagnostics (including labs, cultures, RVP), and antibiotic use. Descriptive statistics, Fisher exact test, linear regression, and Welch’s ANOVA were performed. Results Among 347 fever episodes, the mean age of neonates was 72.8 ± 21.6 days, and 45.2% were female. Out of 30 total RVP samples analyzed, 2 were positive (6.7%). The most common causes of fever were post-procedural (5.7%), pneumonia (4.8%), urinary tract infection (3.5%), meningitis (2.6%), bacteremia (2.3%), or due to a viral infection (2.0%). Antibiotics were started in 208 patients (60%), while 61 neonates (17.6%) were already on antibiotics. The mean length of antibiotics was 7.5 ± 0.5 days. Neonates were more likely to get started on antibiotics if they had a negative RVP compared to those without a negative RVP (89% vs. 11%, p-value < 0.0001). Patients with a positive RVP had a decreased length of stay compared to those without a positive RVP (30.3 ± 8.7 vs. 96.8 ± 71.3, p-value 0.01). On multivariate linear regression, a positive RVP was not associated with length of stay. Conclusion Neonates with a negative respiratory viral PCR test were more likely to be started on antibiotics for fevers. Respiratory viral PCR testing can be used as a tool to promote antibiotic stewardship in the NICU. Disclosures All Authors: No reported disclosures

Evaluation of the Efficacy of Enoxaparin in the Neonatal Intensive Care Unit

2019 ◽  
Author(s):  
Diane Song ◽  
Jacqueline Magers ◽  
Mahmoud Abdel-Rasoul ◽  
Pavel Prusakov
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Cox Model ◽  
Factor Xa ◽  
Retrospective Chart Review ◽  
P Value ◽  
Bleeding Events ◽  
Days Of Therapy

Abstract Objective This article evaluates the efficacy of enoxaparin when targeting anti-factor Xa levels of 0.5 to 1 units per milliliter in the neonatal intensive care unit. Study Design This is a retrospective chart review of 45 neonates receiving enoxaparin for the treatment of venous thromboembolism. Enoxaparin dosing and corresponding anti-factor Xa levels were collected. Time to resolution of clot was confirmed by imaging and compared between clots in various locations. Results The median time to clot resolution was 76 days (interquartile range 40–91 days). Clot location, postnatal age, and sex at the clot onset were significantly associated with time to clot resolution in a multivariable Cox model (p-value: 0.03, 0.03, and < 0.01, respectively). Of the 54 patients analyzed for safety, 5 patients (9.3%) experienced bleeding events resulting in the discontinuation of enoxaparin. Conclusion Based on our findings, 50% of all patients evaluated, regardless of thrombus location, achieved resolution within the first 76 days of therapy. Clots located in the extremities tended to resolve sooner, hence earlier reimaging should be considered.

scholarly journals Pengaruh Musik Keroncong selama Pelaksanaan Kangaroo Mother Care terhadap Respons Fisiologis dan Lama Rawat Bayi dengan Berat Badan Lahir Rendah

2015 ◽  
Vol 10 (2) ◽  
pp. 93
Author(s):  
Anita Rahmawati ◽  
Endah Marianingsih Theresia ◽  
Yuliasti Eka Purnamaningrum
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Low Birthweight ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Purposive Sampling

AbstrakKangaroo mother care (KMC) merupakan metode merawat bayi beratbadan lahir rendah (BBLR). Beberapa intervensi perawatan di neonatal intensive care unit seperti pijat bayi, KMC, dan mendengarkan musik bermanfaat untuk pertumbuhan bayi berupa respons fisiologis BBLR dan mengurangi lama rawat. Penelitian ini bertujuan untuk mengetahui manfaat musik keroncong terhadap respons BBLR selama KMC dan lama rawat. Rancangan penelitian adalah quasi eksperimental dengan pretest dan posttest dengan desain grup kontrol. Pada Juli - September 2014 populasi penelitian adalah ibu dan bayi BBLR yang melaksanakan KMC. Pengambilan sampel dengan purposive sampling sebanyak 60 bayi. Kriteria inklusi bayi BBLR yang ditetapkan adalah berat badan bayi 1.500 – 2.499 gram, tanpa memandang usia kehamilan, bayi mampu menghisap walaupun masih lemah, tidak mengalami kesulitan pernapasan. Kriteriaeksklusi adalah bayi dengan kelainan kongenital, gejala sepsis, dan bayi yang dilakukan foto terapi. Uji statistik menggunakan uji-t berpasangan, ujit independen dengan nilai p < 0,05 dan CI 95%. Setelah perlakuan hari ketiga, terjadi penurunan nadi pada bayi dengan BBLR 8,13 kali/menit (nilai p = 0,000), respirasi penurunannya 2,36 kali/menit (nilai p = 0,000). Rerata lama rawat bayi pada kelompok perlakuan adalah 8,57 hari, sedangkan kelompok kontrol adalah 11,87 hari (nilai p = 0,038). Suhu hasilnya tidak bermakna (nilai p > 0,05). Dapat disimpulkan bahwa musik keroncong berpengaruh terhadap penurunan nadi, respirasi selama KMC, dan lama rawat bayi.AbstractKangaroo Mother Care (KMC) is nursing care method for low birthweight(LBW) infants. Some care interventions in neonatal intensive care unit, such as infant massage, KMC and listening to music have advantage for infant growth in form of physiological responses and reduce LBW infant-nursing length. This study aimed to determine advantage of keroncong music toward LBW infant’s response during KMC and nursing length. The study design was quasi experimental using pretest and posttest using control group design. Population was mothers and LBW infants implementing KMC. Samples were 60 infants taken by purposive sampling. Inclusion criteria determined for LBW infants were having weight 1,500 – 2,499 gram, without considering pregnancy age, having ability to suckle though still weak, not suffering breathing distress. Meanwhile, exclusion criteria were infants with congenital disorder, sepsis symptoms and infants during therapy photo. Statistical test used paired t-test, independent t-test with p value < 0.05 and confidence interval (CI) 95%. After third day of treatment, LBW pulse decreased 8.13 times/minute (p value = 0.000), respiration decreased 2.36 times/minute (p value = 0.000). Nursing length mean on the treatment group was 8.57 days, while the control group was 11.87 days (p value = 0.038). Temperature result was insignificant (p value > 0.05). In conclusion, keroncong music influences on decrease of pulse, respiration during KMC and length of infant nursing.

scholarly journals Perinatal outcome of meconium stained amniotic fluid among labouring mothers at teaching referral hospital in urban Ethiopia

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242025
Author(s):  
Lemi Belay Tolu ◽  
Malede Birara ◽  
Tesfalem Teshome ◽  
Garumma Tolu Feyissa
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Amniotic Fluid ◽  
Neonatal Sepsis ◽  
Perinatal Outcome ◽  
Neonatal Intensive Care ◽  
P Value ◽  
Operative Delivery ◽  
Meconium Stained Amniotic Fluid

Objective To determine the perinatal outcome of labouring mothers with meconium-stained amniotic fluid (MSAF) compared with clear amniotic fluid at teaching referral hospital in urban Ethiopia. Methods A prospective cohort study was conducted among labouring mothers with meconium-stained amniotic fluid from July 1 to December 30, 2019. Data was collected with pretested structured questionnaires. A Chi-square test used to check statistical associations between variables. Those variables with a p-value of less than 0.05 were selected for cross-tabulation and binary logistic regression. P-value set at 0.05, and 95% CI was used to determine the significance of the association. Relative risk was used to determine the strength and direction of the association. Result Among 438 participants, there where 75(52.1%) primigravida in a stained fluid group compared to112 (38.5%) of the non-stained fluid group. Labour was induced in 25 (17.4%) of the stained fluid group compared to 25(8.6%) of a non-stained fluid group and has a statistically significant association with meconium staining. The stained fluid group was twice more likely to undergo operative delivery compared with a non-stained fluid group. There were more low Apgar scores at birth (36.8% versus 13.2%), birth asphyxias (9% versus 2.4%), neonatal sepsis (1% versus 5.6%), neonatal death (1% versus 9%), and increased admissions to neonatal intensive care unit (6.2% versus 21.5%) among the meconium-stained group as compared to the non-stained group. Meconium aspiration syndrome was seen in 9(6.3%) of the stained fluid group. Conclusion Meconium-stained amniotic fluid is associated with increased frequency of operative delivery, birth asphyxia, neonatal sepsis, and neonatal intensive care unit admissions compared to clear amniotic fluid.

scholarly journals 1140. Evaluation of Neonatal Sepsis Guidelines in a Neonatal Intensive Care Unit

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S406-S406
Author(s):  
Priya V Patel ◽  
Colleen B Nash ◽  
Betty N Vu
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Preliminary Data ◽  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
Chi Square ◽  
Before And After ◽  
Implementation Period ◽  
Culture Negative

Abstract Background Clinical practice surrounding neonatal sepsis varies significantly among physicians. In efforts to confront the challenge of inappropriate and overuse of antimicrobials in our Neonatal Intensive Care Unit (NICU), a multidisciplinary team developed a guideline for the evaluation and management of suspected and proven sepsis within the NICU in preterm infants. We evaluated the antimicrobial utilization before and after the implementation of our guideline, developed in July 2018. Methods All infants <37 gestational weeks born in July and August of 2016, 2017, and 2018 were retrospectively reviewed and compared before and after implementation of the guideline. The primary outcome was the percentage of antibiotic-free days per admission. Secondary outcomes include percentage of directive treatment courses and percentage of antibiotic days for culture-negative sepsis. Chi-square and Mann–Whitney U tests were performed, as appropriate. Results A total of 75 and 37 patients were included for preliminary data analysis in the pre- and post-implementation periods, respectively. Chi-square and Mann–Whitney U tests were performed, as appropriate. The percentage of antibiotic-free days per admission per patient born in the pre-implementation period was lower (84.4% vs. 86.5%, P = 0.028). There is no statistical difference in the percentage of directive treatment between the two groups. The percentages of culture-negative antibiotic days were not statistically significant (69.2% vs. 80.5%, P = 0.296). The average birth weights were lower (1,719.7 grams vs. 1,420.7 grams, P = 0.02) and gestational ages were younger (31.4 weeks vs. 29 weeks, P = 0.001) in the post-implementation period. Conclusion Our preliminary data did not show a significant decline in the percentage of antibiotic-free days or culture-negative antibiotic days after the implementation of our guideline; however, this may be confounded by the differences noted in our patient populations and is based on preliminary data. Implementation of this guideline is feasible and may reduce the inappropriate use of antimicrobials. Further data collection is ongoing to fully assess the impact of this guideline. Disclosures All authors: No reported disclosures.

scholarly journals Neonatal Mortality and Its Associated Factors among Neonates Admitted to Wollega University Referral Hospital Neonatal Intensive Care Unit, East Wollega, Ethiopia

2021 ◽  
Vol 8 ◽  
pp. 2333794X2110301
Author(s):  
Tesfaye Abera ◽  
Lami Bayisa ◽  
Teshome Bekele ◽  
Mulugeta Dessalegn ◽  
Diriba Mulisa ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Mortality ◽  
Logistic Regression Analysis ◽  
Neonatal Intensive Care ◽  
Multiple Logistic Regression Analysis ◽  
Birth Asphyxia

Ethiopia has a high neonatal mortality rate in spite of dearth of study. Therefore we aimed to assess magnitude and associated factors of neonatal mortality among neonates admitted to neonatal intensive care units of Wollega University Referral Hospital. Accordingly, a facility based cross-sectional study was conducted on 289 by reviewing medical records of neonates admitted to neonatal intensive care unit. The collected data were entered in to Epi data version 3.1 and Stata version 14 used for analysis. Variables with P-value  < 0.25 at with 95% confidence interval in binary logistic regression analysis were taken to the multiple logistic regression analysis. Finally, variables with Likewise, variable with P-value < 0.05 at 95% confidence interval in multiple logistic regression analysis were considered as statistically significant. Among 289 neonates admitted to neonatal intensive care unit, 53 (18.34 %) were died. Majority 42(79.25%) of those deaths occurred at ≤ 7 days of birth. Preterm [AOR 4.15, 95% CI (1.67-10.33)], neonates faced birth asphyxia [AOR 3.26, 95% CI (1.33-7.98)], neonates who developed sepsis [AOR 2.29 95% CI (1.01-5.20)] and neonates encountered with jaundice [(AOR 11.08, 95% CI (1.03-119.59)] were more at risk to die. In general, the magnitude of neonatal mortality among neonates admitted to neonatal intensive care unit was high. Gestational age (maturity of new born), birth asphyxia, neonatal sepsis and neonatal jaundice were predictors of neonatal mortality. Neonates admitted to neonatal intensive care unit with sepsis, jaundice, and birth asphyxia demand special attention to reduce neonatal mortality.

scholarly journals Emphasise the role of kangaroo mother care in stabilisation of vitals and weight gain pattern in low birth weight babies inside neonatal intensive care unit

2021 ◽  
Vol 8 (4) ◽  
pp. 721
Author(s):  
Shwetal M. Bhatt ◽  
Khushboo N. Mehta ◽  
Ankita Maheshwari ◽  
Priyanka C. Parmar
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Weight Gain ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Kangaroo Mother Care ◽  
P Value

Background: Kangaroo mother care (KMC) is routinely practiced in post-natal wards for care of stable low birth weight (LBW) infants. Objectives of the study were conducted to emphasize on the role of KMC in vitals stabilization and weight gain in LBW babies inside neonatal intensive care unit (NICU).Methods: Cross-sectional analytical quantitative study.Results: A total of 80 babies (48 males and 32 females) were enrolled and given KMC inside NICU. Mean birth weight was 1330 grams. Mean gestational age was 33 weeks (range 30-38 weeks). KMC was initiated within 72 hours of life in majority of babies (71%). Though 65% of them required oxygen support via prongs, KMC was started in them, with monitoring of vitals. No episode of apnea was observed during KMC sessions. Mean duration of KMC was 6 days (3-14 days). Heart rate dropped by 3-4 beats per minute (150+2.12 to 146+1.63, Respiratory rate decreased from 53+3.9 to 49+2.7, Oxygen saturation improved by 2-3% (93+0.42 to 96+0.71). Temperature rose from 36.78+0.01 to 37.07+0.02. P value for all vitals was 0.0001, which is considered significant (<0.05). Average weight gain was 76 grams during the average 6 days of KMC inside NICU, (p value=0.0001).  Conclusions: KMC was found to be effective for stabilization of vitals in NICU, early initiation and upgradation of feeding, early achievement of weight gain pattern, and early shift to postnatal ward by mother’s side. Also, no adverse effects were noted on the babies.

scholarly journals Neonatal outcome in neonatal intensive care unit Sanglah Hospital: Assessed by SNAPPE- II score

2021 ◽  
Vol 8 (2) ◽  
pp. 038-044
Author(s):  
Ida Ayu Agung Wijayanti ◽  
Putu Junara Putra ◽  
I Made Kardana ◽  
I Wayan Dharma Artana ◽  
Made Sukmawati
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Length Of Stay ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Mortality ◽  
Neonatal Intensive Care ◽  
Neonatal Outcome ◽  
Antibiotic Usage ◽  
P Value ◽  
Mortality And Morbidity

Neonatal mortality is topic of concern for many medical faculties. Recently Score for Neonatal Acute Physiology with Perinatal Extension-II (SNAPPE-II) is used to predict the mortality and morbidity of neonates in neonatal intensive care unit (NICU). This study aimed to find the association of mortality and morbidity among neonates using SNAPPE-II score in NICU of Sanglah Hospital with cross-sectional design. All newborns admitted in NICU within 48 hours of birth since January - December 2020 were recruited as sample and assessed by using SNAPPE-II. Statistical analysis was performed by using Chi-square test and Mann–Whitney U test. Eighty-three newborns fulfilled inclusion criteria. In the mortality group, 75.6% had SNAPPE score ≥ 37 and 24% had SNAPPE score <37. SNAPPE-II score ≥ 37 showed an association with mortality group in NICU (p-value 0.000). Moreover, subgroup analyst of neonatal outcome in survived group related to SNAPPE-II score showed significant different in length of stay (P=0.033), ventilator usage (P=0.017) and duration of antibiotic usage (P=0.049). The Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE-II) is a useful tool to assess severity of illness and mortality. SNAPPE-II score > 37 is associated with neonatal mortality. The high SNAPPE-II score in the survived group also affects length of stay in NICU, ventilator and antibiotic usage. These findings imply that SNAPPE-II can be applied routinely in NICU to know the most critical newborn for prioritizing the management of care and for counselling the parents.

scholarly journals SNAPPE II: ANALYSIS OF ACCURACY AND DETERMINATION OF THE CUTOFF POINT AS A DEATH PREDICTOR IN A BRAZILIAN NEONATAL INTENSIVE CARE UNIT

2020 ◽  
Vol 38 ◽  
Author(s):  
Maria Marcia Farias Trajano Fontenele ◽  
Cristiana Ferreira Silva ◽  
Álvaro Jorge Madeiro Leite ◽  
Eveline Campos Monteiro Castro ◽  
Francisco Herlânio Costa Carvalho ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Logistic Regression ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Cutoff Point ◽  
Bivariate Analysis ◽  
Multiple Logistic Regression ◽  
Operating Characteristics ◽  
Prospective Longitudinal

ABSTRACT Objective: To analyze the accuracy of the Score for Neonatal Acute Physiology Perinatal Extension (SNAPPE II) as a death predictor, to determine the cutoff point for mortality, and to analyze the association of independent variables with death. Methods: Prospective, longitudinal, hospital-based study on newborns admitted to the Neonatal Intensive Care Unit (NICU) for the first time from November 1, 2016 to April 30, 2017. Newborns with less than 12 hours of length of stay at the NICU, out-of-hospital births, major congenital malformations, and inter-hospital transfer were excluded. Variables were grouped according to hierarchical framework, related to maternal characteristics (distal level), prenatal and childbirth care (intermediate level), and birth conditions (proximal level). Descriptive analyses of SNAPPE II score ranges, Receiver Operating Characteristics Curve (ROC curve) to define the cutoff point for mortality, and bivariate analysis by the Wald test and multiple logistic regression were conducted. Results: After selection, the sample consisted of 247 newborns. In this study, the SNAPPE II cutoff point for mortality was 27, with sensitivity of 84.1% and specificity of 82.4%. 61% of those with a score ≥27 died. Multiple logistic regression showed an association between death and proximal-level variables: sepsis (Odds Ratio [OR] 10.68; 95% confidence interval [95%CI] 2.82–40.48; p<0.001); SNAPPE II ≥27 (OR 5.85; 95%CI 1.90–18.05; p=0.002); birth weight 750–999 g (OR 4.15; 95%CI 1.06–16.14; p=0.040); and nonuse of surfactant (OR 0.159; 95%CI 0.04–0.53; p=0.003). Conclusions: Neonatal mortality was directly proportional to increase in SNAPPE II. Score≥27 increased the odds of dying by six times compared with neonates with lower scores. The proximal variables related to health conditions and neonatal care were associated with death.

scholarly journals Frequency of Confirmed Congenital Renal Malformations in Neonates with Antenatal Diagnosis of Renal Anomalies Presenting In Neonatal Intensive Care Unit of a Tertiary Care Setting of a Low Income Country.

2021 ◽  
Author(s):  
Qurat-Ul-Ain Siddique ◽  
ABID JAMALI ◽  
Sanober Fatima ◽  
Jai Parkash
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Antenatal Diagnosis ◽  
P Value ◽  
Renal Anomalies ◽  
Renal Malformation ◽  
Renal Malformations

Abstract INTRODUCTION:: Approximately 20 to 30% of all anomalies identified in the prenatal period are congenital anomalies of the kidney and urinary tract (CAKUT). Widespread antenatal screening has resulted in increased detection of anomalies of the kidneys and urinary tract. There are limited studies on the postnatal confirmation of these antenatally detected renal malformations. Moreover, there is no local data available in this regard. So, we conducted the study so that we can obtain local data as well as we can plan management and prevention protocols for such chronically, and sometimes critically, ill neonates. MATERIALS AND METHODS:: It was a cross-sectional study conducted at the neonatal intensive care unit (NICU) at the National Institute of Child Health, Karachi during 2017-2018. The sample size was 100 cases. The sampling technique was non-probability consecutive sampling. All neonates aged 1-28 days of either gender admitted in NICU with antenatal diagnosis of congenital renal anomalies on anomaly scan were included in the study. Preterm neonates (gestational age below 34 weeks) and neonates having siblings with similar congenital problems were excluded. RESULTS:: The mean age of the neonates in our study was 10.17 ±9.30 days and the mean gestational age at birth was 36.65 ±1.16 weeks. The majority of the neonates, that is 65%, were males while 35% were females. Sixty-six per cent (66%) neonates were ≤10 days of age while 34% were >10 days of age. Fifty five% of the neonates were ≤36 weeks of gestation at birth while 45% were >36 weeks of gestation at birth. Frequency of postnatally confirmed congenital renal malformation was observed in 78 (78%) neonates. Neonates whose age at presentation was >10 days were slightly more likely to have confirmed congenital renal malformation as compared to neonates with ≤10 days of age, which is 85.3 % vs 74.2 % (p-value 0.206). Males and females were found to have almost equal postnatally confirmed congenital renal malformations (78.5 % in males and 77.1% in females) (p-value 0.879). Postnatally confirmed congenital renal malformations were observed more commonly in neonates who were >36 weeks of gestational age (80%) as compared to those ≤36 weeks of gestational age (76.4%) (p-value 0.662). CONCLUSION::The frequency of confirmed congenital renal malformation was found higher in neonates presenting with antenatal diagnosis of renal anomalies presenting in the neonatal intensive care unit.

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