Use of a combined acellular vaccine against pertussis infection in children over four years of age: a cross-sectional study

An increase in the incidence of whooping cough has been noted in recent years in both unvaccinated and vaccinated children and adults. In Russia, recently, new possibilities of protection against pertussis infection have appeared for children over four years old and adults. Purpose: to analyze the specific immunoprophylaxis and safety of the vaccine against diphtheria, tetanus and pertussis for children over four years old in Krasnodar. Materials and methods. We examined 393 children over four years and 125 adults who were immunized with a vaccine for the prevention of diphtheria (with a reduced antigen content), tetanus, pertussis (acellular), combined, adsorbed (Adasel) at the SKIB city hospital in Krasnodar in the period from July 2018 until October 2019. The respondents had a vaccination history and did not suffer from whooping cough, according to medical records. Results. The number of people vaccinated with acellular vaccine doubled among the child population (2018 - 129; 2019 - 264) and adults (2018 - 39; 2019 - 86). General post-vaccination reactions among children amounted to 12.2% (48), weak responses prevailed - 36 (9.2%), strong responses were found in 12 people (3%). In adults, general post-vaccination responses were not observed. Local post-vaccination reactions among children amounted to 38.2% (150), weak reactions prevailed - 103 (26.2%), strong ones were found in 47 children (12%). Conclusions. During the study period, immunoprophylaxis with this vaccine doubled, showing a satisfactory safety profile. However, to reduce the incidence of whooping cough, it is advisable to examine the immunological protection and conduct revaccination with a booster dose to achieve stable post-vaccination immunity.

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Afebrile pneumonia (whooping cough) syndrome in infants at Hospital Universitario del Valle, Cali, 2001-2007

Colombia Medica ◽

10.25100/cm.v43i2.1138 ◽

2012 ◽

pp. 114-118 ◽

Cited By ~ 5

Author(s):

Dolly Villegas ◽

Connie Alejandra Echandía-Villegas ◽

Carlos Armando Echandía

Keyword(s):

Medical Records ◽

Whooping Cough ◽

Developed Countries ◽

Cross Sectional Study ◽

Vaccination Status ◽

Sectional Study ◽

Cross Sectional ◽

Young Infants ◽

Atypical Pathogens ◽

Etiologic Diagnosis

Introduction: Afebrile pneumonia syndrome in infants, also called infant pneumonitis, pneumonia caused by atypical pathogens or whooping cough syndrome is a major cause of severe lower respiratory infection in young infants, both in developing countries and in developed countries. Objective: To describe children with afebrile pneumonia syndrome. Methods: Through a cross-sectional study, we reviewed the medical records of children diagnosed with afebrile pneumonia treated at Hospital Universitario del Valle, a reference center in southwestern Colombia, between June 2001 and December 2007. We obtained data on maternal age and origin, prenatal care, the child’s birth, breastfeeding, vaccination status, symptoms, signs, diagnosis, treatment, and complications. Results: We evaluated 101 children with this entity, noting a stationary presentation: June-August and November- December. A total of 73% of the children were under 4 months of age; the most common symptoms were: cyanotic and spasmodic cough (100%), respiratory distress (70%), and unquantified fever (68%). The most common findings: rales (crackles) (50%), wheezing and expiratory stridor (37%); 66% were classified as mild and of the remaining 33%, half of them required attention in the intensive care unit. In all, there was clinical diagnosis of afebrile pneumonia syndrome in infants, but no etiologic diagnosis was made and despite this, 94% of the children received macrolides. Conclusions: These data support the hypothesis that most of these patients acquired the disease by airway, possibly caused by viral infection and did not require the indiscriminate use of macrolides.

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Clinical pattern and predictors of stroke treatment outcome among hospitalised patients who had a stroke at Felege Hiwot comprehensive specialised hospital, northwest Ethiopia: a retrospective cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2020-040238 ◽

2020 ◽

Vol 10 (12) ◽

pp. e040238

Author(s):

Belayneh Kefale ◽

Amien Ewunetei ◽

Mulugeta Molla ◽

Gobezie Temesgen Tegegne ◽

Amsalu Degu

Keyword(s):

Treatment Outcome ◽

Treatment Outcomes ◽

Medical Records ◽

Cross Sectional Study ◽

Northwest Ethiopia ◽

Cross Sectional ◽

Stroke Treatment ◽

Clinical Pattern ◽

Hospitalised Patients ◽

Poor Treatment

ObjectivesThis study aimed to assess the clinical pattern and predictors of stroke treatment outcomes among hospitalised patients in Felege Hiwot comprehensive specialised hospital (FHCSH) in northwest Ethiopia.DesignA retrospective cross-sectional study.SettingThe study was conducted medical ward of FHCSH.ParticipantsThe medical records of 597 adult patients who had a stroke were included in the study. All adult (≥18 years) patients who had a stroke had been admitted to the medical ward of FHSCH during 2015–2019 were included in the study. However, patients with incomplete medical records (ie, incomplete treatment regimen and the status of the patients after treatment) were excluded in the study.ResultsIn the present study, 317 (53.1%) were males, and the mean age of the study participants was 61.08±13.76 years. About two-thirds of patients (392, 65.7%) were diagnosed with ischaemic stroke. Regarding clinical pattern, about 203 (34.0%) of patients complained of right-side body weakness and the major comorbid condition identified was hypertension (216, 64.9%). Overall, 276 (46.2%) of them had poor treatment outcomes, and 101 (16.9%) of them died. Patients who cannot read and write (AOR=42.89, 95% CI 13.23 to 111.28, p<0.001), attend primary school (AOR=22.11, 95% CI 6.98 to 55.99, p<0.001) and secondary school (AOR=4.20, 95% CI 1.42 to 12.51, p<0.001), diagnosed with haemorrhagic stroke (AOR=2.68, 95% CI 1.62 to 4.43, p<0.001) and delayed hospital arrival more than 24 hours (AOR=2.92, 95% CI 1.83 to 4.66, p=0.001) were the independent predictors of poor treatment outcome.ConclusionsApproximately half of the patients who had a stroke had poor treatment outcomes. Ischaemic stroke was the most predominantly diagnosed stroke type. Education status, types of stroke and the median time from onset of symptoms to hospitalisation were the predictors of treatment outcome. Health education should be given to patients regarding clinical symptoms of stroke. In addition, local healthcare providers need to consider the above risk factors while managing stroke.

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Inadequate Gestational Weight Gain and Exposure to Second-Hand Smoke during Pregnancy Increase the Risk of Low Birth Weight: A Cross-Sectional Study among Full-Term Infants

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18031068 ◽

2021 ◽

Vol 18 (3) ◽

pp. 1068

Author(s):

Muliana Edi ◽

Yit Chin ◽

Fui Woon ◽

Geeta Appannah ◽

Poh Lim ◽

...

Keyword(s):

Weight Gain ◽

Birth Weight ◽

Pregnant Women ◽

Medical Records ◽

Cross Sectional Study ◽

Second Hand Smoke ◽

Sectional Study ◽

Cross Sectional ◽

Shs Exposure ◽

At Home

Despite the advancement of the healthcare system, low birth weight (LBW) remains as one of the leading causes of under-five mortality. This cross-sectional study aimed to determine the prevalence of LBW and its associated factors among 483 third trimester pregnant women recruited from six selected public health clinics in the Federal Territory of Kuala Lumpur and the state of Selangor, Malaysia. Pregnant women were interviewed for information on socio-demographic characteristics, smoking behaviour, and second-hand smoke (SHS) exposure at home and in the workplace. Information on the obstetrical history and prenatal care visits history were retrieved from the maternal medical records, while infant’s birth outcomes were retrieved from infant medical records. The prevalence of LBW (<2.5 kg) in infants was 10.4%, with a mean birth weight of 3.0 [standard deviation (SD) 0.4] kg. Results from the multivariable logistic regression model showed that inadequate weight gained during pregnancy [odds ratio (OR) = 2.41, 95% confidence interval (CI) = 1.18–4.90] and exposure to SHS at home (OR = 1.92, 95% CI = 1.03–3.55) were significantly associated with LBW. In conclusion, pregnant women should monitor their rate of weight gain throughout pregnancy and avoid SHS exposure at home to reduce the risk of delivering LBW infants.

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Ophthalmologists and WhatsApp: Teleophthalmology is already here

European Journal of Ophthalmology ◽

10.1177/11206721211002694 ◽

2021 ◽

pp. 112067212110026

Author(s):

Edward Barayev ◽

Ofri Vorobichik Berar ◽

Gad Dotan ◽

Alon Skaat ◽

Orly Gal-Or ◽

...

Keyword(s):

Medical Records ◽

Cross Sectional Study ◽

Work Hours ◽

Clinical Settings ◽

Sectional Study ◽

Cross Sectional ◽

Policy Makers ◽

Media Messages ◽

Rapid Responses ◽

Wide Availability

Purpose: To estimate the extent of WhatsApp utilization using text and media messages for inter-physician consultations among ophthalmologists (residents and specialists) at various clinical settings and its perceived benefits for ophthalmologists and their patients. We also aimed to detect obstacles that concern ophthalmologists when using WhatsApp as a consultation platform. Methods: This was a cross-sectional study using a self-administered survey through Google Forms, which was sent to 660 practicing ophthalmologists during April to May 2020. Results: One hundred and ninety-two ophthalmologists completed the questionnaire, 151 of which (78.6%) were specialists and 41 (21.4%) were residents. Most ophthalmologists reported using WhatsApp at least once a day for both personal and professional use. Residents reported lower rates of contacting patients using WhatsApp than specialists (1.51 ± 0.98 vs 2.72 ± 1.32, p < 0.001). Respondents reported WhatsApp consultations frequently replaced referrals of patients to other physicians, with a median of once a week. 97.8% of residents and 91.4% of specialists reported the ability to share media is a major advantage of WhatsApp over other medias, followed by rapid responses for consultations. Conclusion: Many ophthalmologists already use WhatsApp as a tool for professional consultations with other providers, mainly thanks to its simplicity and wide availability. Residents use it more frequently than specialists, and ranked it higher when asked how much WhatsApp has improved the clinical setting. Policy makers should address concerns brought up by physicians, such as documentation in medical records and proper compensation for consulting ophthalmologists during and after work hours.

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Radiologic imaging of congenital gastrointestinal anomalies in infants

Paediatrica Indonesiana ◽

10.14238/pi52.6.2012.341-5 ◽

2012 ◽

Vol 52 (6) ◽

pp. 341

Author(s):

Leny Zabidi ◽

Gatot Irawan Sarosa ◽

Farah Prabowo

Keyword(s):

Medical Records ◽

Cross Sectional Study ◽

Duodenal Atresia ◽

Congenital Megacolon ◽

Time Data ◽

Pyloric Atresia ◽

Cross Sectional ◽

Radiologic Findings ◽

Radiologic Imaging ◽

Congenital Gastrointestinal Anomalies

Background Congenital gastrointestinal anomalies may manifestsigns or symptoms in the first few days of life, most commonly inthe fonn of obstructions. Radiologic imaging plays an importantrole in diagnosis confirmation and surgical correction plans. Mostcases may be diagnosed by plain radiographs alone, but cr scansand MRI may be needed to make accurate diagnoses, especiallyin difficult cases.Objective To report radiologic imaging findings in infants Mthcongenital gastrointestinal anomalies.Methods For this retrospective, cross􀁊sectional study we tooksecondary data from medical records of infants 'With congenitalgastrointestinal anomalies in Dr. Kariadi Hospital, Semarang,Indonesia from January 2010 - June 2011. Diagnosis of congenitalanomalies was confirmed by clinical manifestation and radiologicimaging. Radiologic findings were reviewed by a single radiologiston duty at that time. Data is presented in the form of frequencydistribution.Results Subjects consisted of 50 males and 23 females. The mostcormnon complaints were vorrritingin 14 subjects (19%), alxlominaldistension in 31 subjects (43%), and fecal passage dysfunction in28 subjects (38%). Radiologic imaging of subjects with congenitalgastrointestinal anomalies revealed the folloMng conditions: analatresia in 28 subjects (38%), congenital megacolon in 21 subjects(29%), esophageal atresia in 14 subjects (19%), duodenal atresia in9 subjects (12%), and pyloric atresia in 1 subject (2%).Conclusion Using radiologic imaging of infants with congenitalgastrointestinal anomalies, the most to least common conditionsfound were anal atresia, congenital megacolon, esophagealatresia, duodenal atresia, and pyloric atresia. [Paediatr Indones.2012;52:341-5].

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Mohs micrographic surgery: a study of 83 cases

Anais Brasileiros de Dermatologia ◽

10.1590/s0365-05962012000200006 ◽

2012 ◽

Vol 87 (2) ◽

pp. 228-234 ◽

Cited By ~ 7

Author(s):

Flavianne Sobral Cardoso Chagas ◽

Bruno de Santana Silva

Keyword(s):

Cell Carcinoma ◽

Medical Records ◽

Cross Sectional Study ◽

Mohs Micrographic Surgery ◽

Micrographic Surgery ◽

Cross Sectional ◽

The Mean ◽

Nasal Region ◽

Cure Rates ◽

Observation Period

BACKGROUND: Mohs micrographic surgery can achieve high cure rates in the treatment of skin cancer and remove a minimum of healthy tissue. OBJECTIVES: To characterize patients undergoing Mohs micrographic surgery and study issues related to the number of surgical stages. METHODS: A descriptive, retrospective, cross-sectional study was conducted in a micrographic surgery reference center for the period of 2004 to 2010. Data was collected from medical records of 79 patients (83 surgeries). RESULTS: We studied 43 women and 36 men. The mean age was 57.5 ± 14,6 years. Skin types II and III were the most frequent, accounting for 41% and 36.1%, respectively. The most frequent tumor was the basal cell carcinoma (89.1%), and the solid subtype was the most common (44.6%), followed by sclerodermiform histological subtype (32%).The most frequent location was the nasal region (44.6%). The large majority of the operated tumors were recurrent lesions (72.7%). Half of the tumors measured 2 cm or more. In 68.7% of the cases two or more surgical stages were necessary for the removal of the tumors. The observation period was 2 or more years in 75% of the tumors. There was 01 post-Mohs recurrence and 02 patients had metastases during the observation period (both with squamous cell carcinoma). CONCLUSION: The findings coincide with those of the literature, recurrent tumors and tumors larger than 2cm needed more surgical stages for their removal, although there was no statistic difference (p=0,12 and 0,44 respectively).

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PROFILE OF PATIENTS RECEIVING TOTAL KNEE ARTHROPLASTY: A CROSS-SECTIONAL STUDY

Acta Ortopédica Brasileira ◽

10.1590/1413-785220172505168806 ◽

2017 ◽

Vol 25 (5) ◽

pp. 202-205 ◽

Cited By ~ 1

Author(s):

MARCELO JOSÉ CORTEZ BEZERRA ◽

IGOR MAGALHÃES BARBOSA ◽

THALES GONÇALVES DE SOUSA ◽

LARISSA MEIRELES FERNANDES ◽

DIEGO LEONARDO MENEZES MAIA ◽

...

Keyword(s):

Medical Records ◽

Severe Disease ◽

Functional Limitation ◽

Cross Sectional Study ◽

Level Of Evidence ◽

Cross Sectional ◽

Lequesne Index ◽

Total Knee ◽

Epidemiological Profile

ABSTRACT Objective: To describe the epidemiological profile, presented deformities, associated comorbidities, and impact on quality of life in patients with knee osteoarthritis. This study was conducted in a philanthropic hospital in Fortaleza from 2014 to 2015. Methods: Data were collected from medical records, epidemiological forms, and by applying the Lequesne index questionnaire, which contains several questions related to pain, discomfort and functional limitation to assess the severity of symptoms. Results: Females were more prevalent (76.7%), as were patients over 65 years of age (61.6%) and non-whites (81.6%). As for comorbidities, 83.3% had hypertension and 31.7% had diabetes. Of the total, 76.5% cases were genu varum, and 23.5% genu valgum. According to the Lequesne index findings, 61.6% cases were “extremely severe,” and women had higher scores. Conclusion: Females were more prevalent and whites were less prevalent. The most frequent comorbidity was hypertension. Female and elderly patients have more severe disease according to Lequesne index score, and these findings were statistically significant. Level of Evidence II, Prospective Study.

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Identification of inappropriate prescribing in a Brazilian nursing home using STOPP/START screening tools and the Beers' Criteria

Brazilian Journal of Pharmaceutical Sciences ◽

10.1590/s1984-82502014000400027 ◽

2014 ◽

Vol 50 (4) ◽

pp. 911-918 ◽

Cited By ~ 3

Author(s):

Mariana Martins Gonzaga Nascimento ◽

Andréia Queiroz Ribeiro ◽

Mariana Linhares Pereira ◽

Adriana Cristina Soares ◽

Antônio Ignácio de Loyola Filho ◽

...

Keyword(s):

Nursing Home ◽

Medical Records ◽

Inappropriate Medication ◽

Inappropriate Prescribing ◽

Cross Sectional Study ◽

Screening Tools ◽

Beers Criteria ◽

Cross Sectional ◽

The Past ◽

Prescribing Omissions

The objective of this study was to determine the prevalence of Potentially Inappropriate Medication (PIM) use and associated factors, as well as the prevalence of Prescribing Omissions (PO). A cross-sectional study was conducted in a philanthropic Brazilian nursing home involving 46 individuals aged 60 years or older. The following information was collected from medical records and drug prescriptions: gender, age, health conditions and drugs used in the past thirty days. PIM and PO were identified according to the Beers' Criteria and the STOPP/START screening tools. Over one third (37%) of the population used at least one PIM according to the Beers' Criteria (n=17) and 60.9% according to the STOPP tool. A significant association was found between polypharmacy (use of five or more drugs) and use of PIM according to the Beers' Criteria, but not according to the STOPP. Eight residents (17.4%) were exposed to eight PO. This study allowed the diagnosis of a concerning drug utilization profile with use of a high number of PIMs. Thus, there is an evident need to implement strategies for improving geriatric prescription.

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Hepatitis B antibody titers in Indonesian adolescents who received the primary hepatitis B vaccine during infancy

Paediatrica Indonesiana ◽

10.14238/pi53.3.2013.160-6 ◽

2013 ◽

Vol 53 (3) ◽

pp. 160

Author(s):

Hartono Gunardi ◽

Adra Firmansyah ◽

Sri Rezeki S Harun ◽

Sudigdo Sastroasmoro

Keyword(s):

Hepatitis B ◽

Booster Dose ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Blood Tests ◽

Vaccination History ◽

Antibody Titers ◽

Hb Vaccine ◽

Over Time

Backgi-ound Hepatitis B (HB) has been classified as moderate-tohighlyendemic in Indonesia. HB vaccination, the most effectivemethod to prevent HB viral transmission, induces protectiveantibodies against HB surface antigen (anti-HBs). However, theseantibodies decline in titer over time. Studies on the duration ofprotection and the prevalence of n on-responders in Indonesianadolescents have been limited.Objectives To determine anti-HBs titers in 15-17-year oldIndonesian adolescents given primary HB vaccine during infancyand the prevalence of non-responders after a HB vaccine boosterdosage.Methods This cross-sectional study was performed from Februaryto September 2008 on adolescents aged 15-17 years in threesenior high schools in Jakarta who received complete primary HBvaccines during infancy, based on parents' recall. Investigationsincluded HB vaccination history, anthropometric measurements,and blood tests for anti-HBs before and 4-6 weeks after a boosterdose ofHB vaccine.Results Of 94 subjects, 35 had protective anti-HBs and 59 hadundetectable anti-HBs. A booster dose was administered to 5 8 of then on-protected subjects, of which 33 showed anamnestic responses.However, 25 subjects failed to generate protective anti-HBs. Takinginto consideration the adolescents with protective anti-HBs beforeand after the booster dose, serologic protection was demonstratedin 73%. Non-responder prevalence was 27%. The high prevalenceof non-responders may indicate bias of parents' recall.Conclusion Protective anti-HBs is detected in less than half ofIndonesian adolescents given primary HB vaccine during infancy.Following booster dosage, anamnestic responses are n oted in onethirdof subjects. The prevalence of non-responders is 27%, butconfirmation with further study is needed.

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Chronic stress, work-related daily challenges and medicolegal investigations: a cross-sectional study among German general practitioners

BMC Family Practice ◽

10.1186/s12875-019-1032-6 ◽

2019 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Christine Kersting ◽

Lena Zimmer ◽

Anika Thielmann ◽

Birgitta Weltermann

Keyword(s):

Regression Model ◽

General Practitioners ◽

Chronic Stress ◽

Medical Records ◽

High Strain ◽

Well Being ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Work Related

Abstract Background The prevalence of chronic stress among German general practitioners (GPs) was shown to be twice as high as in the general population. Because chronic stress negatively influences well-being and poor physician well-being is associated with poor patient outcomes, targeted strategies are needed. This analysis focuses on work-related factors associated with high chronic stress in GPs. Methods This cross-sectional study measured chronic stress among German GPs using the validated and standardized Trier Inventory for the Assessment of Chronic Stress (TICS-SSCS). Based on the TICS, GPs were categorized as either having low strain (≤ 25th percentile) or high strain (≥ 75th percentile) due to chronic stress. Questions on work-related challenges assessed the frequency and the subjectively perceived strain of single challenges. For exploratory analyses, these items were combined to dichotomous variables reflecting challenges that are common and that cause high strain. Variables significant in bivariate analyses were included in a multivariate logistic regression model analyzing their association with high chronic stress. Results Data of 109 GPs categorized as having low strain (n = 53) or high strain (n = 56) due to chronic stress were analyzed. Based on bivariate analyses, challenges regarding personnel matters, practice software, complexity of patients, difficult patients, care facilities, scheduling of appointments, keeping medical records up-to-date, fee structures, and expectations versus reality of care were included in the regression model. Keeping medical records up-to-date had the strongest association with high chronic stress (odds ratio 4.95, 95% confidence interval 1.29–19.06). A non-significant trend showed that medicolegal investigations were more common among GPs with high chronic stress. Conclusions This exploratory research shows that chronic stress is predominantly associated with administrative challenges. Treatment documentation, which represents a legal safeguard and is closely linked to existential concerns, has the strongest influence.

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