scholarly journals A Study on Prevalence of Serum Resistant & Sensitive Escherichia Coli in Urinary Tract Infection

2020 ◽  
Vol 9 (4) ◽  
pp. 1-6
Author(s):  
K. Prakash ◽  
J. Shravan Kumar ◽  
J. Rajamouli ◽  
Sachin Gurnule

Background: Escherichia coli is the commonest organism causing urinary tract infection in women and children especially in those with uncom- plicated infections. It has been traditionally described Serotypes of Escherichia coli were consistently associated with Uropathogenicity and designated as Uropathogenic Escherichia coli.It is now recognized that a subset of fecal Escherichia coli can be colonized in the peri-urethral area, enter the urinary tract and cause symptomatic disease. These are currently defined as Uropathogenic Escherichia coli. The aims & objectives are to the isolation of Escherichia coli in Urinary tract infection. 2. To determine the prevalence of Serum resistant Uropathogenic Escherichia coli. 3. To compare antimicrobial efficacy in Serum resistant and Serum sensitive Uropathogenic Escherichia coli. Subjects & Methods: An observational study was conducted on 100 patients and urine samples collected from suspected and suffering from urinary tract infection. Study period from August 2018 to July 20019 attending General medicine OP in Hospital. Escherichia coli were isolated and identified by conventional techniques Mackie & Mc Cartney. The strains were subjected to multiple drugs to study serum resistance and sensitivity. Results: From 100 urine samples 71 Uropathogenic, 18 males & 53 females. 40% Sero-resistant and 60% Sero-sensitive among them 2 to 18 years males and > 40 years females resistant, above 40 years males and 19 to 40 years females are sensitive to multiple antibiotics. Conclusion: it emphasizes Serum resistance is an important virulence factor, It may lead to pyelonephritis and septicemia. Serum resistant E. coli are multiple drug-resistant, so the present study formulating guidelines for planning effective treatment and Periodic surveillance to monitor resistance.

2020 ◽  
Vol 17 (35) ◽  
pp. 621-627
Author(s):  
May Ali Hussien UMRAN ◽  
Sumaya Najim AL-KHATEEB

The bacterium Escherichia coli is one of the best free-living organisms studied in depth. It is a surprisingly diverse species, since some strains of E. coli live in the intestine of animals as harmless commensals, while other distinct genotypes, such as an enteropathogenic or enterohemorrhagic E. coli, for example, cause morbidity and death marked as human intestinal pathogens. The purpose of this study was to develop and validate a PCR assay for a known and suspected uropathogenic E. coli virulence factor (kpsMT) gene region to determine the distribution of the gene and its role in the development of clinical diseases of the urinary system. A total of 25 urine samples were collected from patients with urinary tract infection (UTI) at Azadi and Kirkuk hospitals in the city of Kirkuk, Iraq. Samples of both genders and different ages were collected from patients with suspected urinary tract infection according to the clinical manifestations and symptoms diagnosed by the examining physician. The samples were cultured and positive samples were subjected to the IMViC test to identify E. coli bacteria and subsequently identified using the Vitek 2 compact system. Among 25 samples, 24 (96%) showed positive results for bacterial cultural growth. Of these, 17 (68%) were identified as Escherichia coli. Of the total of 17 isolates, 14 from patients with mild urinary tract infection, and 3 from patients with Urosepsis. The kpsMT gene was present in 14 isolates (82.3%), including 11 (78.5%) isolates from patients with mild urinary tract infection, and 3 (100%) isolates from patients with Urosepsis. It was concluded that Escherichia coli is the most prevalent in urine tract infection samples. Due to the abundance of the kpsMT gene in uropathogenic Escherichia coli (UPEC), this gene plays an important role in developing UTI if it is not treated correctly and quickly; mild cases of UTI can turn into Urosepsis.


2015 ◽  
Vol 2 (4) ◽  
pp. 31990-31990 ◽  
Author(s):  
Fariha Akhter Chowdhury ◽  
Mohammad Nurul Islam ◽  
Anamika Saha ◽  
Sabrina Mahboob ◽  
Abu Syed Md. Mosaddek ◽  
...  

2020 ◽  
Vol 9 (33) ◽  
Author(s):  
Belle M. Sharon ◽  
Amber Nguyen ◽  
Amanda P. Arute ◽  
Neha V. Hulyalkar ◽  
Vivian H. Nguyen ◽  
...  

ABSTRACT Uropathogenic Escherichia coli (UPEC) is the most common cause of urinary tract infection (UTI). This disease disproportionately affects women and frequently develops into recurrent UTI (rUTI) in postmenopausal women. Here, we report the complete genome sequences of seven UPEC isolates obtained from the urine of postmenopausal women with rUTI.


2018 ◽  
Vol 40 (6) ◽  
pp. 625-634 ◽  
Author(s):  
Dong Ho Kim ◽  
Bindu Subhadra ◽  
Hee Young Kang ◽  
Kyungho Woo ◽  
Jaeseok Kim ◽  
...  

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