scholarly journals Relationship of Scabies and Iron Deficiency Anemia in Children of 3-12 Year Age Group: A Hospital Based Survey

Author(s):  
Dr Jagriti Narayan ◽  
Author(s):  
Muhammed Nizamudheen C H ◽  
Soumya S B

This study is an attempt to clinically analyze the independent effect of Karimbirumbadi kashayam and Vasaguluchiadi kashayam in Panduroga and also compare their efficacy. Aims and Objectives: To evaluate the comparative efficacy of Karimbirumbadi kashayam and Vasaguluchyadi kashayam in Panduroga with special reference to iron deficiency anemia in the reproductive age group of women. Methodology: Among 46 registered subjects, 22 were registered in group A and 24were registered in group B. Out of which 20 subjects of A group and 20 subjects of B group completed the study. Group A was administered with 25ml of Karimbirumbadi kashayam with 40ml of luke warm water twice daily before food for 2 months and Group B was administered with 25ml of Vasaguluchyadi kashayam with 40ml of luke warm water and 10ml of Madhu as Anupana twice daily before food for 2 months. Objective and subjective parameters were analyzed using paired T test and Wilcoxon signed rank test respectively. Independent T test and Mann-Whitney U test were used to compare the parameters between the groups. Result: There was statistically significant improvement in the objective and subjective parameters (p<0.05 was observed). Conclusion: The study shows that both Karimbirumbadi kashayam and Vasaguluchyadi kashayam are effective in relieving the symptoms of Panduroga. Symptomatic relief was seen in both the group A & B, but there was no statistically significant difference between the groups in relieving these symptoms.


Author(s):  
Rashmi Pareek Ayatullah Hosne Asif ◽  
Nisha Kumari Ojha

Background: Anemia in adolescent girls possess greatest burden on their health as it leads to poor cognitive development, poor reproductive health and if not treated may lead to intrauterine growth retardation in their developing fetus. The prevalence of anemia among adolescent is 27% in developing country and 6% in developed country. The Government of India has launched National Anemia Control Programme, to prevent and control anaemia in children and adolescents. But the problem is still persisting because of many issues like - poor palatability, intolerance to the drug used, poor absorption of the drugs used, constipation, discoloration of stool, unpleasant odor and taste etc. result in poor compliance and therefore non adherence to the therapy which finally results in poor improvement. By looking at the magnitude of the problem, an Ayurveda drug Vajravatakmandura has been selected for the study and the present study was undertaken to evaluate the efficacy of the trial drug in iron deficiency anemia in adolescent girls. Material and methods: 100 subjects satisfying inclusion and exclusion criteria were selected and were randomly divided in two groups. In group A, the trial drug Vajravatakmaņdura was administered and in group B, IFA tablets were given for two month of duration with follow up at every fortnight. Result: Both the trial and control groups showed extremely significant result over subjective parameters. Trial drug Vajravatakmaņdura in group A was found more effective over the subjective parameters - weakness, palpitation, pallor and loss of appetite with % gain of 39.77%, 39.39%, 39.17%, 38.09% respectively. Statistical analysis between before and after treatment findings of objective parameters, extremely significant (P less than 0.0001) improvement was found in both groups in all parameters, except for RBC count in group A, which was significant. No adverse effects were reported during entire period of study by any of the patients in trial group treated with trial drug. Conclusion: The trial drug “Vajravatakmandura” is effective, safe and palatable for the management of iron deficiency anemia in adolescent girls.


2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Efrat Broide ◽  
Ram Reifen ◽  
Shay Matalon ◽  
Zipi Berkovich ◽  
Haim Shirin

The role of iron transport proteins in the pathogenesis of anemia in patients with diabetes mellitus (T2DM) is still unclear. We investigated the expression of duodenal transporter proteins in diabetic patients with and without iron deficiency anemia (IDA). Methods. Overall, 39 patients were included: 16 with T2DM and IDA (group A), 11 with T2DM without IDA (group B), and 12 controls (group C). Duodenal mucosal expression of divalent metal transporter 1 (DMT1), ferroportin 1 (FPN), hephaestin (HEPH), and transferrin receptor 1 (TfR) was evaluated by Western blotting. Chronic disease activity markers were measured as well. Results. FPN expression was increased in group A compared to group B and controls: 1.17 (0.72–1.46), 0.76 (0.53–1.04), and 0.71 (0.64–0.86), respectively (p=0.011). TfR levels were over expressed in groups A and B compared to controls: 0.39 (0.26–0.61), 0.36 (0.24–0.43), and 0.18 (0.16–0.24), respectively, (p=0.004). The three groups did not differ significantly with regard to cellular HEPH and DMT1 expression. The normal CRP and serum ferritin levels, accompanied with normal FPN among diabetic patients without IDA, do not support the association of IDA with chronic inflammatory state. Conclusion. In patients with T2DM and IDA, duodenal iron transport protein expression might be dependent on body iron stores rather than by chronic inflammation or diabetes per se.


Author(s):  
Dr. Manish Kumar

Iron deficiency results in the decreased synthesis of important molecules including iron containing enzymes thereby inducing cellular organic functional disturbances. If not corrected in a timely manner, iron deficiency anemia (IDA) will ensue. The consequences of iron deficiency anemia (IDA) range from impaired psychological and physical well-being and decreased occupational abilities to developmental troubles in children and increased morbidity and mortality in some patient populations. Moreover, iron deficiency is a risk factor in various medical settings because it impedes erythropoietic response to acute and chronic anemia. Hence based on above findings the present study was planned to evaluate the levels of iron in rheumatoid The present study was planned in Department of General Medicine, All India Institute of Medical Sciences, Patna from jan 2018 to june 2018. Group A consist of 30 informed male and female consented patients diagnosed with Rheumatoid arthritis were enrolled for the study. The group B consist of 30 control patients for comparative evaluation. Hence from present study it can be concluded that, there is no known prevention for iron deficiency anaemia in rheumatoid arthritis (RA) patients other than the reduction of contributory factors. Therapy goals are to reduce pain and inflammation and improve quality of life. Surgery to repair, replace or fuse joints may help in serious conditions. Keywords: Rheumatoid Arthritis, Iron Deficiency, Heamoglobon, Iron, etc.


2021 ◽  
Vol 74 (10) ◽  
pp. 2433-2438
Author(s):  
Zoriana I. Piskur ◽  
Lidiia I. Mykolyshyn

The aim: To study the structure of clinical forms of tuberculosis (TB) which are combined with the comorbidities, to prevent the development, and to improve the diagnostics of TB among children with nonspecific diseases. Materials and methods: A retrospective, selective research of 330 cards of children for the age group from 0 to 15 years old who were treated on local forms of pulmonary and extrapulmonary TB in a specialized pediatric department for the last 30 years was conducted. Results: Among 92.9 % children with comorbidities, the specific process of respiratory system was detected. Every seventh child has developed generalized forms of pulmonary TB. 43.8 % of children had extrapulmonary TB. In the structure of comorbidities among children with extrapulmonary TB were observed iron deficiency anemia, the diseases of digestive and endocrine systems, malnutrition, cachexia and rickets. The iron deficiency anemia was accompanied by TB of the peripheral LN and TB of the CNS. TB of the rare localization and TB of the CNS were combined with diseases of the digestive system. At pulmonary TB were detected infectious and parasitic diseases. The concomitant pathology of the respiratory and cardiovascular systems was often detected with the TB of intrathoracic LN, and concomitant pathology of the eyes, ears and CNS – with primary tuberculosis complex. The variety of comorbidities and extrapulmonary TB has led to the diagnostic errors and prolonged stay of children in several somatic hospitals. Conclusions: To prevent the development of TB among children with non-specific diseases, it is necessary to strengthen anti-TB measures among them.


2014 ◽  
Vol 36 (2) ◽  
pp. 134-139 ◽  
Author(s):  
Natalina Miguel ◽  
Emília Costa ◽  
Marta Santalha ◽  
Rosa Lima ◽  
José Ramon Vizcaino ◽  
...  

Author(s):  
Urvashi Verma ◽  
Saroj Singh ◽  
Shikha Singh ◽  
Anu Pathak ◽  
Poonam Yadav ◽  
...  

Background: Objective of present study was to evaluate the efficacy and safety of intravenous bolus iron sucrose for iron deficiency anemia during pregnancy during second and third trimester women presenting at S.N. medical college, Agra.Methods: It was a prospective controlled trial and study was carried out in Department of Obstetrics and Gynecology, S.N. medical college, Agra in the year 2014-2016. 100Pregnant women with proved iron deficiency anemia having hemoglobin between 4-9gm/dl was included in this study. Total Iron deficit was calculated by standard formula. Target haemoglobin was 11gm/dl. Iron sucrose was administered by intravenous bolus and intravenous infusion techniques. Hemoglobin was repeated at 2 weeks, 4 weeks and 8 weeks after the last dose of intravenous iron sucroseResults: In Group A (bolus group n=50) 22 women had gestational age >24-28weeks and 20 women gestational age >18-24 weeks, with Mean gestational age of 24.36±3.78 weeks. In Group B (infusion group n=50) most of the patients 24 (48%) had gestational age >24-28 weeks, 18 (36%) had gestational age >18-24 weeks, with Mean gestational age of 24.94±3.51 weeks. Target hemoglobin was achieved in group A in all 50 (100%) cases and in group B in 49 (98%) cases. There were no allergic reactions.Conclusions: This study showed a significant improvement in the hemoglobin of the patients after receiving intravenous bolus and intravenous infusion of iron sucrose. Patients achieved the target hemoglobin of 11gm/dl. Both therapies are safe, effective and faster acting for the treatment of iron deficiency anaemia during pregnancy. The bolus push technique is more convenient to women and care provider, less time consuming as well as cost effective.


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