scholarly journals Indigenous wisdom of Ayurvedic drugs to treat Urinary tract infections

2020 ◽  
Vol 11 (3) ◽  
pp. 370-377
Author(s):  
Prashant S Bhokardankar ◽  
Bharat Rathi

Urinary tract infections (UTI) in all ages are related with high morbidity and long term difficulties. Use of antibiotics is useful in cases of UTI, consequently opposition of pathogenic microorganisms to antibiotics  is of high clinical concern. According to Ayurveda drugs especially important components which have been utilized for the treatment of various diseases. The review paper highlighted different clinical studies and scientific studies which are useful to prove the adequacy of Ayurveda drugs against urinary tract infections. Ayurvedic  drugs were reviewed in the current paper in the awake of evaluating their well being for the clinical condition like UTI. Ayurvedic medications showed good anti bacterial properties against both gram positive and negative microscopic organisms causing UTI. Other aspects are highlighted  likewise mitigating, diuretic, cell reinforcement, nephroprotective and antiurolithiatic properties helpful in the administration of UTI and all medications are protected even in high dosages subsequently can be adequately utilized for UTI conditions. In this paper an attempt is made to highlight the research work of herbal drugs of Ayurveda which would be effective in the treatment of UTI. 

2019 ◽  
Vol 13 (3) ◽  
pp. 125-132 ◽  
Author(s):  
Nikos Sabanis ◽  
Eleni Paschou ◽  
Panagiota Papanikolaou ◽  
Georgios Zagkotsis

Background/Aims: Purple urine bag syndrome (PUBS) is an uncommon clinical entity characterized by purple urine discoloration in the setting of urinary tract infections. Pa-thophysiology of PUBS has been correlated to aberrant metabolism of tryptophan. Multiple predisposing factors have been recognized, namely: female gender, advanced age, constipation, institutionalization, long-term catheter-ization, dementia and chronic kidney disease. Herein, we present a comprehensive review of all PUBS cases reported in PubMed, focusing on the predisposing factors and the microorganisms related to PUBS. Methods: We performed a search in PubMed database for articles referring to PUBS, published in English, French, Spanish and German from January 1978 until November 2017. The literature recruitment strategy was based on several keywords and Medical Subject Heading combination such as “purple urine bag syndrome” or PUBS or “urine discoloration”. The finally selected articles were categorized into case reports/series (88 articles including 112 patients) and studies (10 articles including 134 patients). Demographical data as well as predisposing factors were recorded and further analyzed. Results: According to our findings, mean age of PUBS patients was 78.9 ± 12.3 years, 70.7% were female while 90.1% were suffering from constipation, 76.1% were in a bedridden situation, 45.1% were experiencing long-term catheterization, 42.8% had been diagnosed with dementia, 14.3% had recurrent urinary tract infections and 14.1% were chronic kidney disease patients. 91.3% of patients presenting with PUBS alkaline urine were observed while the most common microbe in urine cultures was E. coli. Conclusions: PUBS is considered benign process in the majority of catheterized patients. Clinicians should be aware of the syndrome that may indicate serious comorbidities.


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