The Relationship Between Periodontal Disease And Blood Glucose Level Among Type II Diabetic Patients

2001 ◽  
Vol 2 (4) ◽  
pp. 1-6 ◽  
Author(s):  
Khalid Almas ◽  
Mohammed Al-Qahtani ◽  
Marzouk Al-Yami ◽  
Nazeer Khan

Abstract The aim of this study was to determine the relationship between periodontal disease and the blood glucose level among type II non-insulin dependent diabetic mellitus (NIDDM) subjects. Forty subjects, 20 in each group, of healthy and diabetic subjects, ages ranged 20-70 years, were examined at King Saud University, College of Dentistry. Clinical examination included frequency of oral hygiene practices, periodontal status by using the Community Periodontal Index of Treatment Needs (CPITN), fasting blood glucose level (FBGL), and random blood glucose level (RBGL). Unstandardized orthopantomograms (OPGs) were taken for radiographic findings. The number of missing teeth (tooth loss) was assessed from the radiographs. The results showed that periodontal disease severity was high among diabetic subjects. Diabetic subjects brushed less frequently, and they had a higher blood glucose level than healthy subjects. The mean CPITN score was compared with mean blood glucose level and the severity of periodontal disease. There was a steady increase in blood glucose level with increase in CPITN scores, i.e., CPITN score 13.5 to 19.12 corresponded with 142 mg/dl and 173.2 mg/dl FBGL, and 184.2 and 199.12 mg/dl RBGL among diabetic subjects. The study indicated that diabetic subjects should improve their oral hygiene practices and control of blood glucose levels should be emphasized. Further studies are needed among diabetics and healthy subjects from the general population with better sampling techniques and a larger sample size. Citation Almas K, Al-Qahtani M, Al-Yami M, Khan N. The Relationship Between Periodontal Disease And Blood Glucose Level Among Type II Diabetic Patients. J Contemp Dent Pract 2001 Nov;(2)4: 018-025.

1969 ◽  
Vol 3 (2) ◽  
pp. 346-349
Author(s):  
HARESH KUMAR ◽  
MONA RANI ◽  
MOHAMMAD HANIF ◽  
KHEMOMAL A. KARIRA ◽  
MOHAMMAD MUNIB ◽  
...  

BACKGROUND: Hair is a dead tissue and is composed of keratin and related proteins. Hair is a protein offew growing cells at the base of the hair root. If the patient is diabetic glycosylation occurs in these growingcells.Since the extent of glycation of hair protein varies with the distance from the hair root, we hypothesizedthat glycation of hair protein might provide insight into blood glucose level over a period of several mouthsto one year.So hemoglobin Ale (HbAIc) may be established as an indicator of long-term blood glucosecontrol in diabetic patients. It is formed by non-enzymatic reaction of glucose with Hb.The objective of thisstudy was to estimate the furosine(an intermediate in the breaking down of amadori compounds likeglycosylated proteins) level by HPLC of glycosylated hair proteins, to find interrelation of fasting glucosewith HbAIc and furosine in diabetic patients, to determine the efficacy of Glycosylation of HbA,c andfurosinemay be a reliable marker in diabetic patients.STUDY DESIGN: This study was carried out in the department of Biochemistry Basic Medical SciencesInstitute (BMSI) Jinnah Postgraduate Medical Centre Karachi.METHODS: A total of 200 subjects were included in the study. 100 diagnosed type II and 100 controlnormal subjects. Hair from the scalp 12 cm long and 50 mg in weight was collected from each subject tomeasure furosine level. Furosine level was determined by HPLC and HbAIc, FBSand serumprotein byenzymatic kit method.RESULTS: When the mean values were compared with that of control it depicted significantly high level(0.001) of furosine, HbAIc and FBS.CONCLUSION: The furosine, HbAIc and FBS levels increases in diabetic patients while total serumprotein were unaffected. Weight and BMI increases in diabetic but height was unaffected.KEYWORDS: Diabetes mellitus type II, furosine, HbAIc, fasting blood sugar, glycation ofhair protein


1969 ◽  
Vol 11 (4) ◽  
pp. 181-184
Author(s):  
Muhammad Tariq Khan ◽  
Muhammad Ilyas ◽  
Salman Khan ◽  
Jawad Ahmad Kundi ◽  
Fariha Kifayat

Background: The rate of type II diabetic patients is increasing and results in oral manifestations. The oral surgery needsextraordinary measures in these patients.Objective: To assess the effect of anesthetic agent with 1:100,000 epinephrine and without epinephrine in the blood glucose levelof diabetic patients.Material and Methods: This was a randomized study of 60 patients having type 2 diabetes mellitus who were undergoing toothextraction. The study was double blind. 30-70years aged patients were selected. Blood glucose level was monitored 15 minutesbefore giving local anesthesia and after 20 minutes of the injection. ANOVA was used for comparison between groups.Results: No significant difference was seen in glycemic level using local anesthesia with 1:100,000 epinephrine (p=0.345). Therewas slight decrease noted in the blood glucose level of both groups.Conclusion: The use of 2% local anesthesia with 1:100,000epinephrine didn't cause hyperglycemia in diabetic patients.Keywords: Diabetes Mellitus, Local Anesthesia, Epinephrine, Tooth Extraction, Lidocaine.


Author(s):  
M. Sagana ◽  
Sreedevi Dharman

Diabetes mellitus (DM) is a clinical syndrome characterized by hyperglycemia because of the absolute or relative deficiency of insulin. It requires frequent monitoring of glucose levels in the body which requires multiple pricking at regular intervals. It could be physically and psychologically traumatic to the patient. This necessitates an alternative to measure the glucose level. This study aims to correlate the salivary glucose level with the blood glucose level in diabetes patients. The cross-sectional study was conducted in 60 patients. Patients were categorized into two groups as Group A- 30 patients with diabetes and Group B- 30 healthy subjects. The blood and saliva samples were collected from the patients and the glucose levels were recorded. All these data were entered in Microsoft Excel and analyzed statistically using SPSS software. The mean (±SD) value of the random blood and salivary glucose level in diabetic patients were found to be 251.4±82.66 and 2.85±0.85 respectively and the mean blood and salivary glucose level in healthy subjects were found to be 101.12±10.14 and 0.875±0.13 respectively. There was a significant correlation between the salivary glucose levels and blood glucose levels among diabetes (p-0.00) and healthy individuals (p-0.00). From the data, the diagnostic accuracy was found to be 100%. Thus, Saliva could be used as an alternative to blood for monitoring the glucose status in diabetes patients.


2020 ◽  

Background and Objectives: Diabetes is one of the most rampant chronic diseases that is accompanied by numerous psychological problems. The present study aimed to compare the effectiveness of compassion-focused therapy (CFT) and attachment-based compassion therapy (ABCT) on blood glucose level and medication adherence in diabetic patients. Materials and Methods: This quasi-experimental study was conducted based on a pretest and posttest design. At first, using the available voluntary sampling method, a number of 45 individuals were selected from 300 diabetic patients referred to Alborz Diabetes Association, Alborz, Iran. They were randomly divided into two experimental and one control groups. At the outset, in addition to the hemoglobin (Hb) A1c blood test, they completed a medication adherence questionnaire. Afterward, the first experimental group participated in eight two-h sessions of the compassionate therapy training course, and the second experimental group participated in 10 90-min sessions of the ABCT training course. All three groups received standard treatment for diabetic patients. At the end of the treatment, the HbA1c levels of blood in all three groups were re-evaluated, and again all patients completed the medication adherence questionnaire at the post-test stage. It should be mentioned that the collected data were analyzed using the analysis of covariance. Results: Based on the results, CFT and ABCT could reduce blood glucose level (HbA1c) (F=5.13, P<0.008, Eta= 0.20) and increase medication adherence (F=2.82, P<0.035, Eta= 0.12) in both of the experimental groups. Conclusion: The CFT and ABCT can be effective in improving medication adherence and blood glucose control (HbA1c) in diabetic patients. Therefore, it is suggested to provide such training together with other medical interventions as part of comprehensive therapy of diabetes.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Riyan Al Islam Reshad ◽  
Sumaiya Hafiz Riana ◽  
Mohammad Al-baruni Chowdhury ◽  
Abu Tayab Moin ◽  
Faruque Miah ◽  
...  

Abstract Background The recent pandemic of coronavirus disease 19 (COVID-19) has been causing intense stress among the global population. In the case of hospitalized and ICU-admitted COVID-19 patients with comorbidities, it has been observed that a major portion of them are diabetic. Therefore, researchers had indicated a link between diabetes mellitus (DM) and COVID-19. Furthermore, DM is a potential risk factor for the severity of COVID-19 cases. Thus, in this study, the correlation existing between diabetic patients and COVID-19 was summarized. Main body of the abstract Diabetic patients have a weaker immune system, less viral clearance rate, malfunctions of metabolic activity due to their high blood glucose level, and other associated problems. This does not increase the susceptibility for the patients to be infected with COVID-19. However, the severity of COVID-19 can worsen due to the comorbidity of DM. Short conclusion Proper management, appropriate use of drugs that do not increase the ACE2 expression, lowering blood glucose level, decreasing the susceptibility of SARS-CoV-2, and maintaining a healthy lifestyle could be effective.


Author(s):  
I. Iwanegbe ◽  
M. Suleiman ◽  
A. Jimah

Aims: To investigate the effect of food blends (plantain, soybean and ginger) on the blood glucose, lipid profile and haematological indices on streptozotocin induced diabetic rats. Methodology: A total of 35 rats of mean body weight 219.07 g separated into7 groups (5 per group) where induced by a single intraperitoneal (I.P) injection of streptozotocin (0.1 g dissolved in 5 ml of freshly prepared sodium citrate buffer 0.1 M, pH 4.5) at a dose of 40 mg/kg body weight after fasting for 12 hours and fed with flours/blends. The flours were produced from plant materials for different treatments/blends (blend A=100% unripe plantain, B=80% unripe plantain, 14% soybean, 6% ginger, C=70% unripe plantain, 26% soybean, 4% ginger, D= 60% unripe plantain, 38% soybean, 2% ginger, E= 50% unripe plantain, 50% soybean) and the phytochemicals and minerals content were determined. Blood glucose was determined at 5 days interval for 25 days. Diabetes was confirmed in rats with blood glucose concentrations >200 mg/dl. After 25 days rats were anaesthetized with chloroform vapour and blood samples collected by cardiac puncture for haematology and lipid profile determination. Results: The results showed that unripe plantain, soya beans and ginger in adequate proportion(C=70% unripe plantain, 26% soybean, 4% ginger or D= 60% unripe plantain, 38% soybean, 2% ginger) could help to reduce blood glucose, improve haematological parameters and lipid profile. Significant reduction was observed in the blood glucose level of rats fed blends C and D from 286 to 85 mg/dl and 307 to 90 mg/dl respectively at the end of experiment. These results also demonstrated that the inclusion of ginger at 6% causes rise in blood glucose level. Total cholesterol (TC) increased in all the blends. However, the lowest concentration of TC was observed in blends C and D. The highest packed cell volume (60%) and Haemoglobin (20 g/dl) level observed in rats fed blend C was significantly higher than the normal control fed conventional feeds. The increase in packed cell volume (PCV) (50%) and Hb (17 g/dl) in diabetic rats demonstrated that the formulated blend C was able to raise PCV and Hb above 50% and 17 g/dl (Normal control NC) respectively. Significant increase (P<0.05) in low density lipoprotein cholesterol (LDLc) was also observed in all the blends with blend C having the least (4.0 mg/dl) close to NC (2.0 mg/dl). Conclusion: From the results it is evident that blend C will manage and improve the health status of diabetic patients.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mrs. Vanitha. S s ◽  
Dr. Pramjit kaur

Challenges in lifestyle, such as increasesin energy intake and decreasesin physical activity are causing overweight and obesity leading to epidemic increases in type II Diabetes Mellitus. The research approach used for this study was evaluative approach and the research design was true experimental design. 60 patients with type II diabetes, 30 in experimental group and 30 in control group were selected for this study by using purposive sampling technique. Data was collected with the help of self-structured interview schedule. Descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (chi-square, paired ‘t’ test) were used to analyse the data and to test the hypotheses. In the experimental group,the pre-test mean score was 2.966, mean percentage was 59% and standard deviation was 1.129 and in post-testmean score was 2.533, mean percentage was 50.66% and standard deviation was 1.074 with effectiveness of 8.34% and paired‘t’ test value of t=3.971,which was statistically significant (p<0.05) which is an evidence ofthe effectiveness of Amla juice in reducing blood glucose level. Comparison of blood glucose levels in experimental and control groups, shows that the value is statistically highly significant, as was observed from the unpaired ‘t’ test value of 13.39 with P value of <0.05, which is an evidence indicatingthe effect of Amla juice in reducing postprandial blood glucose levels. The resultsfound that the administration of Amla juice did have aneffect in reducing blood glucose level in the experimental group. By comparing the findings of pre-test and post test between the experimental group and the control group,the effect was identified (assessed). The study concluded that the Amlajuice is effective in reducing blood glucose level.


2022 ◽  
pp. 96-101
Author(s):  
RT Reethika Rathan ◽  
Saramma Mathew Fenn ◽  
R Karthik ◽  
PT Ravikumar ◽  
Sabitha Gokulraj ◽  
...  

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