scholarly journals Effect of Local Anesthesia with 1:100,000 Epinephrine on Glycemic Level of Type II Diabetic Patients Undergoing Oral Surgery

1969 ◽  
Vol 11 (4) ◽  
pp. 181-184
Author(s):  
Muhammad Tariq Khan ◽  
Muhammad Ilyas ◽  
Salman Khan ◽  
Jawad Ahmad Kundi ◽  
Fariha Kifayat
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Local Anesthesia ◽  
Glucose Level ◽  
Oral Surgery ◽  
Diabetic Patients ◽  
Type Ii ◽  
Glycemic Level ◽  
Significant Difference

Background: The rate of type II diabetic patients is increasing and results in oral manifestations. The oral surgery needsextraordinary measures in these patients.Objective: To assess the effect of anesthetic agent with 1:100,000 epinephrine and without epinephrine in the blood glucose levelof diabetic patients.Material and Methods: This was a randomized study of 60 patients having type 2 diabetes mellitus who were undergoing toothextraction. The study was double blind. 30-70years aged patients were selected. Blood glucose level was monitored 15 minutesbefore giving local anesthesia and after 20 minutes of the injection. ANOVA was used for comparison between groups.Results: No significant difference was seen in glycemic level using local anesthesia with 1:100,000 epinephrine (p=0.345). Therewas slight decrease noted in the blood glucose level of both groups.Conclusion: The use of 2% local anesthesia with 1:100,000epinephrine didn't cause hyperglycemia in diabetic patients.Keywords: Diabetes Mellitus, Local Anesthesia, Epinephrine, Tooth Extraction, Lidocaine.

TO STUDY THE RELATIONSHIP BETWEEN THE GLYCOSYLATED HAIR PROTEIN AND HBA1C FOR ASSESSMENT OF BLOOD GLUCOSE LEVEL IN DIABETES MELLITUS TYPE II

1969 ◽  
Vol 3 (2) ◽  
pp. 346-349
Author(s):  
HARESH KUMAR ◽  
MONA RANI ◽  
MOHAMMAD HANIF ◽  
KHEMOMAL A. KARIRA ◽  
MOHAMMAD MUNIB ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Enzymatic Reaction ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Type Ii ◽  
Hair Root ◽  
Diabetes Mellitus Type Ii

BACKGROUND: Hair is a dead tissue and is composed of keratin and related proteins. Hair is a protein offew growing cells at the base of the hair root. If the patient is diabetic glycosylation occurs in these growingcells.Since the extent of glycation of hair protein varies with the distance from the hair root, we hypothesizedthat glycation of hair protein might provide insight into blood glucose level over a period of several mouthsto one year.So hemoglobin Ale (HbAIc) may be established as an indicator of long-term blood glucosecontrol in diabetic patients. It is formed by non-enzymatic reaction of glucose with Hb.The objective of thisstudy was to estimate the furosine(an intermediate in the breaking down of amadori compounds likeglycosylated proteins) level by HPLC of glycosylated hair proteins, to find interrelation of fasting glucosewith HbAIc and furosine in diabetic patients, to determine the efficacy of Glycosylation of HbA,c andfurosinemay be a reliable marker in diabetic patients.STUDY DESIGN: This study was carried out in the department of Biochemistry Basic Medical SciencesInstitute (BMSI) Jinnah Postgraduate Medical Centre Karachi.METHODS: A total of 200 subjects were included in the study. 100 diagnosed type II and 100 controlnormal subjects. Hair from the scalp 12 cm long and 50 mg in weight was collected from each subject tomeasure furosine level. Furosine level was determined by HPLC and HbAIc, FBSand serumprotein byenzymatic kit method.RESULTS: When the mean values were compared with that of control it depicted significantly high level(0.001) of furosine, HbAIc and FBS.CONCLUSION: The furosine, HbAIc and FBS levels increases in diabetic patients while total serumprotein were unaffected. Weight and BMI increases in diabetic but height was unaffected.KEYWORDS: Diabetes mellitus type II, furosine, HbAIc, fasting blood sugar, glycation ofhair protein

scholarly journals EFFECT OF AEROBIC EXERCISES AND RESISTANCE TRAINING ON GLUCOSE LEVELS IN TYPE 2 DIABETIC SUBJECTS.

2017 ◽  
Vol 10 (7) ◽  
pp. 360
Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Resistance Training ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.

scholarly journals Ekstrak air daun ceplikan (Ruellia tuberosa L.) serta pengaruhnya terhadap kadar glukosa darah dan gambaran histologis pankreas tikus putih (Rattus norvegicus) diabetes mellitus

2009 ◽  
Vol 6 (2) ◽  
pp. 64
Author(s):  
Taufan Hendra Tandri ◽  
Wiryatun Lestariana ◽  
Fatma Zuhrotun Nisa
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Rattus Norvegicus ◽  
Diabetic Rats ◽  
Effective Control ◽  
White Rats ◽  
Group I ◽  
Significant Difference

Background: Effective control of blood glucose and activities of antioxidant are key factors that prevent diabetes mellitus (DM) and its complications. There are lots of herbal plants that have those both effects. Ceplikan leaves (Ruellia tuberosa L.) is a traditional medicine which is empirically used to lower blood glucose level. Instead of antioxidant compound, there is assumed other compound in ceplikan leaves that has side effect to pancreatic beta cells.Objective: To identify the effect of ceplikan leaves extract to blood glucose level and pancreas histology description in white diabetic rats (Rattus norvegicus).Method: Thirty subjects of Wistar strain male white rats of 2-3 months old and of 150-200 grams weight were made diabetic with aloxan and randomly divided into 5 groups. Group I consisted of diabetic rats with aquadest, group II with glibenclamide, and Group III-V were given extract of ceplikan leaves in different concentrations that were 1.6 mg, 3.2 mg, and 6.4mg, respectively. Treatment was given orally per day within 30 days. Level of blood glucose was measured in the day of 0, 3, 4, and 30. Statistical analysis used repeated measures and t-test.Result: The supply of ceplikan leaves extract could reduce level of blood glucose of diabetic rats, although the decrease was insignificant. Average diameter of wider Langerhans island occurred to the group of diabetic rats that were given extract of ceplikan leaves dosage 6.4 mg. There was no significant difference (p > 0.05) in changes of blood glucose level before and after experiment in diabetic rats. Pancreas histological description of rats showed that there was improvement as indicated by greater quantity of Langerhans Island and wider diameter of Langerhans Island.Conclusion: Ceplikan leaves was safe and efficacious, so that self-medication of DM using ceplikan leaves could be sustained through formal approach.

scholarly journals Effectiveness of Coriander Seed Extract in decreasing Blood Glucose level among Diabetic Patients

2020 ◽  
Vol 11 (3) ◽  
pp. 2879-2883
Author(s):  
Sheela R ◽  
Merlin Shiny Sheeba ◽  
Poornima ◽  
Priya
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Low Income ◽  
Seed Extract ◽  
Medical Expenditure ◽  
Diabetic Patients ◽  
Treatment Of Diabetes ◽  
Coriander Seed

Diabetes Mellitus (DM) belongs to a group of metabolic disorders. It is characterised by Chronic Hyperglycemia and disturbance of carbohydrate, lipid and protein metabolism. The cause for this condition arises from a disease in insulin secretion. The International Diabetes Federation (IDF) expresses that worldwide 415 million individuals have Diabetes Mellitus. It also predicts that by 2040 this will ascend to 642 billion. The other prediction is that 77% of individuals with Diabetes live in middle and low-income countries. 12% of the worldwide population spend on the treatment of Diabetes. With the escalating medical expenditure in treating Diabetes, a person from middle or low income may find it challenging to meet the expenses. It is an expected tendency for an individual from this category to opt for a more straightforward treatment that suits their pocket. In the recent past, all over the world, people from all walks of life know essential things about natural remedies. A lot of researches are going on in support of using natural products per se. One such study is this – on the Effectiveness of Coriander Seed Extract in decreasing Blood Glucose level among Diabetic Patients.Coriandrum Sativum is a plant that has been utilised in the administration of Diabetes. It is a herbaceous plant originally from the Mediterranean and Middle Eastern locales, having a place in the family Apiaceae. It is known to have antifungal, antibacterial, free radical searching, and lipid peroxidation activities. The study was conducted to assess the level of pretest and posttest blood glucose level. And, also to evaluate the effect of coriander seed extract in the treatment of Diabetes Mellitus. An experimental study was chosen to assess the effectiveness of coriander seed extract among diabetic clients. The present study was conducted at Mappedu. 60 male and female who come under inclusion criteria were selected by purposive sampling technique. Data was collected by using a socio-demographic variable, and random blood glucose was assessed by CBG machine. The results revealed that coriander seed extract has a significant effect on decreasing blood glucose level among diabetic patients.

scholarly journals Biochemical markers in saliva of patients with diabetes mellitus

2012 ◽  
Vol 59 (4) ◽  
pp. 198-204 ◽  
Author(s):  
Biljana Andjelski-Radicevic ◽  
Radica Dozic ◽  
Tatjana Todorovic ◽  
Ivan Dozic
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Diabetic Patients ◽  
Non Invasive ◽  
Stress Markers ◽  
Frequent Monitoring ◽  
Patients With Diabetes ◽  
Protein Components

Diabetes mellitus is metabolic syndrome characterized by disorder in metabolism of carbon hydrates, lipids and proteins. The diagnosis of diabetes is established by measuring the blood glucose level using standardized methods. Frequent monitoring of blood glucose level could be inconvenient for patients because of possible pain during blood sample taking. In the last few years biological materials with non invasive sampling, like saliva, have been analyzed. Research has confirmed that some organic and inorganic components of saliva are modified in diabetic patients (glucose, lipid and protein components, oxidative stress markers, electrolytes). Beside other markers, the analysis of glucose in saliva is an attempt to find a non-invasive and painless way for frequent monitoring of glucose concentration in diabetic patients. Collecting saliva is simple and economical, it neither requires expensive equipment nor specially trained staff. Saliva can be taken many times and in unlimited quantity. In regards to the data about the possibilities for using saliva as biological sample in monitoring diabetes mellitus, which could be alternative to blood serum or plasma, the conclusion is that saliva becomes more important in this context.

scholarly journals Anti-Diabetic Activity of Polypeptide-K Isolated from Momordica Charantia: A Retrospective Study of 142 Cases

2021 ◽  
Vol 14 (4) ◽  
pp. 2007-2015
Author(s):  
Yong Yean Sirn ◽  
Lee Cheng Lok ◽  
Pak Hoe Weng ◽  
Zuraini Ahmad ◽  
Muhammad Nazrul Hakim
Keyword(s):  
Retrospective Study ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Momordica Charantia ◽  
T Test ◽  
Post Treatment ◽  
Diabetic Patients ◽  
Paired Sample ◽  
Significant Difference

Diabetes Mellitus occurs when the pancreas fails to produce sufficient insulin, or the body is unable to use the insulin produced effectively. In order to regulate the blood glucose of diabetic patients, Diabegard®, a herbal antidiabetic medicine and daily supplement, contains polypeptide-k which exists in the seed of Momordica Charantia (bitter gourd) was prescribed. Purpose: A retrospective study is therefore done with the aim to examine the effectiveness of Diabegard®, polypeptide-k in regulating the blood glucose and cholesterol level of diabetic patients who took Diabegard® for four weeks with a dose of 60 mg per day. Methods: A database record of 105 male and 37 female (ages 25-81) treated with Diabegard®, polypeptide-k was assessed. The effectiveness of Diabegard®, polypeptide-k in blood glucose regulation was determined based on four aspects: gender, three different age categories, four different categories of duration of the disease and five different categories of severity of the disease. The Pearson's correlation was used to find the correlation among variables. Paired sample t-test was used to compare the means of pre- and post-treatment of blood glucose level. One-way ANOVA was used to compare the means of different groups for each aspect. Results: Result showed that age and duration of disease (r2=0.469), pre-treatment of blood glucose and post-treatment of blood glucose (r2=0.606) showed positive relationship. Both paired sample T-test of pre-and post-treatment of blood glucose showed significant difference (p<0.05). Categories with very mild (7 mmol/L), severe (13.9-19.4mmol/L) and very severe (>19.4mmol/L) diabetes showed significant difference (p<0.05). Other tests showed no significant difference. Conclusion: In conclusion, this present retrospective study showed that Diabegard®, polypeptide-k was effective in controlling blood glucose level of all diabetic patients especially in patients with mild (26.87% reduction), severe (40.43% reduction) and very severe diabetes (49.27% reduction).

scholarly journals Achievement of Awareness in a Diabetic Population

1970 ◽  
pp. 7-10
Author(s):  
Mirza Azizul Hoque ◽  
Md Sirajul Islam ◽  
Md Abdul Maleque Khan ◽  
Rehana Aziz ◽  
HAM Nazmul Ahasan
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Educational Status ◽  
Diabetic Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Educational Group ◽  
Diabetic Clinic ◽  
Significant Difference

This cross-sectional survey was carried out during the period, October 2005 to December 2005, among 184 randomly chosen diabetic patients in Khulna Diabetic Centre, Khulna, Bangladesh, to evaluate the knowledge of the patients for their control of diabetes mellitus and also to explore the association(s) of their attitude and knowledge regarding diabetic awareness towards educational status and socio-demographic profile. In this study, we found a significant difference, in diabetic awareness to keep correct blood glucose level, in different educational group. But, it did not influence the subjects of different educational group to visit the diabetic clinic. There was no significant difference in the knowledge of correct blood glucose level and in regularity of visit to the diabetic clinic, in rural and urban people. Knowledge of correct blood glucose level varied significantly among male and female patients, although, no significant variation was found among them in visiting to the diabetic clinic. We can conclude that, diabetic education programs can improve self-regulatory behavior and in the long run, can reduce morbidity and mortality.   doi:10.3329/jom.v10i3.2008 J Medicine 2009; 10 (Supplement 1): 7-10  

The Relationship Between Periodontal Disease And Blood Glucose Level Among Type II Diabetic Patients

2001 ◽  
Vol 2 (4) ◽  
pp. 1-6 ◽  
Author(s):  
Khalid Almas ◽  
Mohammed Al-Qahtani ◽  
Marzouk Al-Yami ◽  
Nazeer Khan
Keyword(s):  
Blood Glucose ◽  
Periodontal Disease ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Oral Hygiene ◽  
Healthy Subjects ◽  
Diabetic Patients ◽  
Type Ii ◽  
Hygiene Practices ◽  
The Relationship

Abstract The aim of this study was to determine the relationship between periodontal disease and the blood glucose level among type II non-insulin dependent diabetic mellitus (NIDDM) subjects. Forty subjects, 20 in each group, of healthy and diabetic subjects, ages ranged 20-70 years, were examined at King Saud University, College of Dentistry. Clinical examination included frequency of oral hygiene practices, periodontal status by using the Community Periodontal Index of Treatment Needs (CPITN), fasting blood glucose level (FBGL), and random blood glucose level (RBGL). Unstandardized orthopantomograms (OPGs) were taken for radiographic findings. The number of missing teeth (tooth loss) was assessed from the radiographs. The results showed that periodontal disease severity was high among diabetic subjects. Diabetic subjects brushed less frequently, and they had a higher blood glucose level than healthy subjects. The mean CPITN score was compared with mean blood glucose level and the severity of periodontal disease. There was a steady increase in blood glucose level with increase in CPITN scores, i.e., CPITN score 13.5 to 19.12 corresponded with 142 mg/dl and 173.2 mg/dl FBGL, and 184.2 and 199.12 mg/dl RBGL among diabetic subjects. The study indicated that diabetic subjects should improve their oral hygiene practices and control of blood glucose levels should be emphasized. Further studies are needed among diabetics and healthy subjects from the general population with better sampling techniques and a larger sample size. Citation Almas K, Al-Qahtani M, Al-Yami M, Khan N. The Relationship Between Periodontal Disease And Blood Glucose Level Among Type II Diabetic Patients. J Contemp Dent Pract 2001 Nov;(2)4: 018-025.

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