Implant Surface Modification and Osseointegration-Past, Present and Future

2014 ◽  
Vol 8 (2) ◽  
pp. 113-118 ◽  
Author(s):  
A Kumar ◽  
V Kumar ◽  
M Goel ◽  
R Mehta ◽  
G Bhayana ◽  
...  
Keyword(s):  
Surface Modification ◽  
Surface Properties ◽  
Dental Implant ◽  
Research Evidence ◽  
Surface Modifications ◽  
Biological Fixation ◽  
Implant Surface ◽  
Jaw Bones

ABSTRACT Biological fixation between the dental implant surfaces and jaw bones should be considered a prerequisite for the long-term success of implant-supported prostheses. The implant surface modifications gained an important and decisive place in implant research over the last years. Nowadays, a large number of implant types with a great variety of surface properties and other features are commercially available and have to be treated with caution. Although surface modifications have been shown to enhance osseointegration at early implantation times, for example, the clinician should look for research evidence before selecting a dental implant for a specific use.

scholarly journals Influence of implant surfaces on osseointegration

2010 ◽  
Vol 21 (6) ◽  
pp. 471-481 ◽  
Author(s):  
Arthur Belém Novaes Jr ◽  
Sérgio Luis Scombatti de Souza ◽  
Raquel Rezende Martins de Barros ◽  
Karina Kimiko Yamashina Pereira ◽  
Giovanna Iezzi ◽  
...  
Keyword(s):  
Dental Implant ◽  
Bone Morphogenetic Proteins ◽  
Dental Treatment ◽  
Surface Modifications ◽  
In Vivo Studies ◽  
Treatment Modalities ◽  
Biological Fixation ◽  
Implant Surface

The biological fixation between the dental implant surfaces and jaw bones should be considered a prerequisite for the long-term success of implant-supported prostheses. In this context, the implant surface modifications gained an important and decisive place in implant research over the last years. As the most investigated topic in, it aided the development of enhanced dental treatment modalities and the expansion of dental implant use. Nowadays, a large number of implant types with a great variety of surface properties and other features are commercially available and have to be treated with caution. Although surface modifications have been shown to enhance osseointegration at early implantation times, for example, the clinician should look for research evidence before selecting a dental implant for a specific use. This paper reviews the literature on dental implant surfaces by assessing in vitro and in vivo studies to show the current perspective of implant development. The review comprises quantitative and qualitative results on the analysis of bone-implant interface using micro and nano implant surface topographies. Furthermore, the perspective of incorporating biomimetic molecules (e.g.: peptides and bone morphogenetic proteins) to the implant surface and their effects on bone formation and remodeling around implants are discussed.

scholarly journals The Impact of Dental Implant Surface Modifications on Osseointegration and Biofilm Formation

2021 ◽  
Vol 10 (8) ◽  
pp. 1641
Author(s):  
Stefanie Kligman ◽  
Zhi Ren ◽  
Chun-Hsi Chung ◽  
Michael Angelo Perillo ◽  
Yu-Cheng Chang ◽  
...  
Keyword(s):  
Dental Implant ◽  
Biofilm Formation ◽  
Bacterial Colonization ◽  
Surface Modifications ◽  
Implant Surface ◽  
Oral Rehabilitation ◽  
Surface Design ◽  
Polyether Ether Ketone ◽  
Dental Implant Surface ◽  
The Impact

Implant surface design has evolved to meet oral rehabilitation challenges in both healthy and compromised bone. For example, to conquer the most common dental implant-related complications, peri-implantitis, and subsequent implant loss, implant surfaces have been modified to introduce desired properties to a dental implant and thus increase the implant success rate and expand their indications. Until now, a diversity of implant surface modifications, including different physical, chemical, and biological techniques, have been applied to a broad range of materials, such as titanium, zirconia, and polyether ether ketone, to achieve these goals. Ideal modifications enhance the interaction between the implant’s surface and its surrounding bone which will facilitate osseointegration while minimizing the bacterial colonization to reduce the risk of biofilm formation. This review article aims to comprehensively discuss currently available implant surface modifications commonly used in implantology in terms of their impact on osseointegration and biofilm formation, which is critical for clinicians to choose the most suitable materials to improve the success and survival of implantation.

Comparison of two dental implant surface modifications on implants with same macrodesign: an experimental study in the pelvic sheep model

2014 ◽  
Vol 26 (8) ◽  
pp. 898-908 ◽  
Author(s):  
Sabrina Ernst ◽  
Stefan Stübinger ◽  
Peter Schüpbach ◽  
Michéle Sidler ◽  
Karina Klein ◽  
...  
Keyword(s):  
Experimental Study ◽  
Dental Implant ◽  
Surface Modifications ◽  
Implant Surface ◽  
Sheep Model ◽  
Dental Implant Surface

scholarly journals Surface Modification of Dental Implants - A Review

2021 ◽  
Vol 10 (17) ◽  
pp. 1246-1250
Author(s):  
Shamaa Anjum ◽  
Arvina Rajasekar
Keyword(s):  
Surface Roughness ◽  
Surface Modification ◽  
Dental Implants ◽  
Surface Engineering ◽  
Surface Modifications ◽  
Calcium Phosphate Coating ◽  
Acid Etching ◽  
Success Rates ◽  
Implant Surface ◽  
Osteoblast Activity

The use of dental implants for the replacement of missing teeth has increased in the last 30 years. The success rates for implant placement depend on a series of both biological and clinical steps which starts with primary stability that is being provided by the amount, quality and the distribution of bone within the proposed implant site. The most important factor in implant osseointegration is surface roughness, which shows increased osteoblast activity at 1 to 100 μm of the surface roughness when compared to a smooth surface. Rough surfaces have excellent osseointegration than smooth surfaces, but the results of research have been diverse, and it is evident that multiple treatments provide good results. The surfaces of a dental implant have been modified in several ways to improve its biocompatibility and speed up osseointegration. Literature says that any surface modification provides a good surface for osseointegration of the implant when the surface roughness is about 0.44 ~ 8.68 μm. It is also said that acid etching and coating are the most preferred methods for creating good roughness of the implant surface. From animal studies, it is known that implant surface modifications provided by biomolecular coating seemed to enhance the osseointegration by promoting peri-implant bone formation in the early stages of healing. It also seemed to improve histomorphometric analysis and biomechanical testing results. This article reviews the surface modifications of dental implants for the achievement of better success rates. Various methods are used to modify the topography or the chemistry of the implant surfaces which includes acid etching, anodic oxidation, blasting, treatment with fluoride, and calcium phosphate coating. These modifications provide a faster and a stronger osseointegration.1 Recently, hydrophilic properties added to the roughened surfaces or some osteogenic peptides coated on the surfaces shows higher biocompatibility and have induced faster osseointegration compared to the existing modified surfaces. With development in surface engineering techniques, new information on the properties, behaviour, and the reaction of various materials could be discovered which in turn allows the discovery of new materials, modification techniques and design of bio implants for the future. KEY WORDS Dental Implants, Surface Modifications, Biocompatibility, Surface Topography

scholarly journals Surface Modification of Porous Polyethylene Implants with an Albumin-Based Nanocarrier-Release System

Biomedicines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1485
Author(s):  
Jonas Eckrich ◽  
Niklas Hoormann ◽  
Erik Kersten ◽  
Keti Piradashvili ◽  
Frederik R. Wurm ◽  
...  
Keyword(s):  
Surface Modification ◽  
Release Kinetics ◽  
Dip Coating ◽  
Porous Polyethylene ◽  
Implant Surface ◽  
High Molar Mass ◽  
Dorsal Skinfold Chamber ◽  
Factor Release

Background: Porous polyethylene (PPE) implants are used for the reconstruction of tissue defects but have a risk of rejection in case of insufficient ingrowth into the host tissue. Various growth factors can promote implant ingrowth, yet a long-term gradient is a prerequisite for the mediation of these effects. As modification of the implant surface with nanocarriers may facilitate a long-term gradient by sustained factor release, implants modified with crosslinked albumin nanocarriers were evaluated in vivo. Methods: Nanocarriers from murine serum albumin (MSA) were prepared by an inverse miniemulsion technique encapsulating either a low- or high-molar mass fluorescent cargo. PPE implants were subsequently coated with these nanocarriers. In control cohorts, the implant was coated with the homologue non-encapsulated cargo substance by dip coating. Implants were consequently analyzed in vivo using repetitive fluorescence microscopy utilizing the dorsal skinfold chamber in mice for ten days post implantation. Results: Implant-modification with MSA nanocarriers significantly prolonged the presence of the encapsulated small molecules while macromolecules were detectable during the investigated timeframe regardless of the form of application. Conclusions: Surface modification of PPE implants with MSA nanocarriers results in the alternation of release kinetics especially when small molecular substances are used and therefore allows a prolonged factor release for the promotion of implant integration.

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