scholarly journals Hoarseness of Voice: A Retrospective Study of 251 Cases

2011 ◽  
Vol 1 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Digvijay Singh ◽  
Hansa Banjara ◽  
Varsha Mungutwar ◽  
Anuj Gupta

ABSTRACT Aims Hoarseness of voice is a common symptom in otolaryngological practice and it is the earliest manifestation of a large variety of conditions directly or indirectly affecting the larynx, ranging from benign to most malignant. This study was undertaken to find out clinical profile, predisposing factors and etiology of hoarseness of voice. Methods A retrospective cohort analysis was carried out in Department of ENT, Pt JNM Medical College, Raipur, in 251 cases of change in voice for 3 years duration. All cases were analyzed for detailed history and underwent pre- and postoperatively stroboscopic examination to reach the diagnosis. Results Total 251 cases with M:F ratio of 1.9:1 were analyzed. Patients age ranged from 11 to 80 years and majority of patients equally presented in 4th and 6th decade. Nonvocal/nonprofessional group constituted as a single largest group (85.26%). Smoking was commonest predisposing factor (44.22%) followed by vocal abuse (30.28%). Out of 251 cases, 83.67% cases were organic and 16.33% cases were functional in origin.

2012 ◽  
Vol 2 (1) ◽  
pp. 23-29
Author(s):  
Rauf Ahmad ◽  
Raja Salman Khurshid ◽  
Mukhtar Ahmad Khan

ABSTRACT Aim This study was undertaken to study the clinical profile of hoarseness and the role of conservative (nonsurgical) and surgical modes of intervention. Materials and methods A prospective cohort analysis was carried out in Department of ENT, Government Medical College, Srinagar, in 145 cases of change in voice for 2 years duration. All cases were analyzed for detailed history and pre- and postoperative fiber optic laryngeal examination. The cases were managed by conventional conservative methods or underwent phonosurgery in nonresolving cases. Results Total 145 cases with M:F ratio of 1.37:1 were analyzed. Patients’ age ranged from 5 to 80 years and majority of patients equally presented in 4th and 6th decade and about 75% had duration of hoarseness of more than 3 months. A voice demanding profession was present in 34% of cases. Vocal abuse was the commonest predisposing factor (about 40%) followed by larygopharyngeal reflux disease (26%). Functional voice disorders were found in 15.85% of cases while 62.06% of patients had a definite organic disorder. Conservative treatment (primary) was employed in 103 cases (71%), surgical treatment (primary) in 42 cases (29%) and surgical treatment after failure of conservative was given in 22 cases (15%). How to cite this article Khurshid RS, Khan MA, Ahmad R. Clinical Profile of Hoarseness and its Management Options: A 2 years Prospective Study of 145 Patients. Int J Phonosurg Laryngol 2012;2(1):23-29.


2020 ◽  
Vol 72 (2) ◽  
Author(s):  
Silvia Alboresi ◽  
Alice Sghedoni ◽  
Giulia Borelli ◽  
Stefania Costi ◽  
Laura Beccani ◽  
...  

Author(s):  
Serena Xodo ◽  
Fabiana Cecchini ◽  
Lisa Celante ◽  
Alice Novak ◽  
Emma Rossetti ◽  
...  

2021 ◽  
Vol 10 (5) ◽  
pp. 1058
Author(s):  
Grégoire Rocher ◽  
Thomas Gaillard ◽  
Catherine Uzan ◽  
Pierre Collinet ◽  
Pierre-Adrien Bolze ◽  
...  

To determine if the time-to-chemotherapy (TTC) after primary macroscopic complete cytoreductive surgery (CRS) influences recurrence-free survival (RFS) and overall survival (OS) in patients with epithelial ovarian cancer (EOC). We conducted an observational multicenter retrospective cohort analysis of women with EOC treated from September 2006 to November 2016 in nine institutions in France (FRANCOGYN research group) with maintained EOC databases. We included women with EOC (all FIGO stages) who underwent primary complete macroscopic CRS prior to platinum-based adjuvant chemotherapy. Two hundred thirty-three patients were included: 73 (31.3%) in the early-stage group (ESG) (FIGO I-II), and 160 (68.7%) in the advanced-stage group (ASG) (FIGO III-IV). Median TTC was 43 days (36–56). The median OS was 77.2 months (65.9–106.6). OS was lower in the ASG when TTC exceeded 8 weeks (70.5 vs. 59.3 months, p = 0.04). No impact on OS was found when TTC was below or above 6 weeks (78.5 and 66.8 months, respectively, p = 0.25). In the whole population, TTC had no impact on RFS or OS. None of the factors studied were associated with an increase in TTC. Chemotherapy should be initiated as soon as possible after CRS. A TTC greater than 8 weeks is associated with poorer OS in patients with advanced stage EOC.


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