scholarly journals Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint

2018 ◽  
Vol 19 (2) ◽  
pp. 242-245 ◽  
Author(s):  
Supriya M Kheur ◽  
Sheetal S Choudhari ◽  
Deepak G Kulkarni ◽  
Sangeeta Patankar
Keyword(s):  
Clinical Significance ◽  
Oral Submucous Fibrosis ◽  
Therapeutic Strategies ◽  
Pathological Angiogenesis ◽  
Prevention And Treatment ◽  
New Strategy ◽  
Submucous Fibrosis ◽  
Fibrotic Disorders

ABSTRACT Oral submucous fibrosis (OSF) is characterized by excessive fibrosis of submucosa. The degree of vascularity in OSF has always been a matter of debate. Angiogenesis is the key mechanism involved in regeneration and repair. It also plays an important role in various pathologic conditions. Angiogenesis may contribute to the progression of fibrosis in fibrotic disorders. Inhibition of pathological angiogenesis is considered to be a new strategy for the treatment of various fibrotic disorders. In OSF, angiogenesis can be related to progression fibrosis. This article briefly describes the role of angiogenesis in pathogenesis of fibrosis in OSF and the importance of inhibition of pathologic angiogenesis in its prevention and treatment. Clinical significance Understanding the association between angiogenesis and fibrogenesis can help in developing new therapeutic strategies for treatment of OSF. How to cite this article Choudhari SS, Kulkarni DG, Patankar S, Kheur SM, Sarode SC, Sarode GS, Patil S. Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint. J Contemp Dent Pract 2018;19(2):242-245.

Stem Cells from Human Exfoliated Deciduous Teeth and their Promise as Preventive and Therapeutic Strategies for Neurological Diseases and Injuries

2021 ◽  
Vol 17 ◽  
Author(s):  
Lingyi Huang ◽  
Zizhuo Zheng ◽  
Ding Bai ◽  
Xianglong Han
Keyword(s):  
Stem Cells ◽  
Potential Role ◽  
Neurological Diseases ◽  
Therapeutic Strategies ◽  
Deciduous Teeth ◽  
Research Attention ◽  
Considerable Potential ◽  
Prevention And Treatment ◽  
Human Exfoliated Deciduous Teeth

Abstract: Stem cells from human exfoliated deciduous teeth (SHEDs) are relatively easy to isolate from exfoliated deciduous teeth, which are obtained via dental therapy as biological waste. SHEDs originate from the embryonic neural crest and therefore have considerable potential for neurogenic differentiation. Currently, an increasing amount of research attention is focused on the therapeutic applications of SHEDs in neurological diseases and injuries. In this article, we summarize the biological characteristics of SHEDs and the potential role of SHEDs and their derivatives, including conditioned medium from SHEDs and the exosomes they secrete, in the prevention and treatment of neurological diseases and injuries.

OI0446 Role of betamethasone in oral submucous fibrosis

2014 ◽  
Vol 117 (5) ◽  
pp. e340
Author(s):  
Kaustubh Sansare ◽  
Heena Sonawane ◽  
Neha Bansal ◽  
Freny Karjodkar
Keyword(s):  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

P140. Role of matrix metallo-proteinase-3 promoter (-1171 5A/6A) polymorphism in oral submucous fibrosis and head and neck lesions

Oral Oncology ◽  
2011 ◽  
Vol 47 ◽  
pp. S119-S120
Author(s):  
A.K. Chaudhary ◽  
S. Pandya ◽  
M. Singh ◽  
A.C. Bharti ◽  
M. Singh ◽  
...  
Keyword(s):  
Head And Neck ◽  
Oral Submucous Fibrosis ◽  
Proteinase 3 ◽  
Submucous Fibrosis

scholarly journals Study of the Role of Salivary Lactate Dehydrogenase in Habitual Tobacco Chewers, Oral Submucous Fibrosis and Oral Cancer as a Biomarker

2019 ◽  
Vol 20 (8) ◽  
pp. 970-973 ◽  
Author(s):  
Sanjay G Thete ◽  
Tejashree Mantri ◽  
Vijayalaxmi Male ◽  
Renu Yadav ◽  
Ishita Grover ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Oral Cancer ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Aloe vera in the management of oral submucous fibrosis

2017 ◽  
Vol 04 ◽  
pp. 1
Author(s):  
Vagish Kumar L Shanbhag ◽  
◽  
Keyword(s):  
Sri Lanka ◽  
Oral Submucous Fibrosis ◽  
Aloe Vera ◽  
Mouth Opening ◽  
Malignant Potential ◽  
Progressive Reduction ◽  
Submucous Fibrosis ◽  
Current Article ◽  
Malignant Condition

Oral submucous fibrosis is a pre-malignant condition commonly prevalent in India, Pakistan, Taiwan and Sri Lanka. Patients characteristically exhibit progressive reduction in mouth opening. The disease has a high malignant potential and thus should be diagnosed and treated at the earliest. However, none of the currently used medical therapies show promising results. The current article briefly reviews the role of Aloe vera in the management of oral submucous fibrosis.

scholarly journals Effectiveness of Long Term Supervised and Assisted Physiotherapy in Postsurgery Oral Submucous Fibrosis Patients

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
S. Kale ◽  
N. Srivastava ◽  
V. Bagga ◽  
A. Shetty
Keyword(s):  
Treatment Options ◽  
Oral Submucous Fibrosis ◽  
Scar Contracture ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Conservative And Surgical Treatment ◽  
Subsequent Relapse

Oral submucous fibrosis is one of the leading potentially malignant disorders prevailing in India. A number of conservative and surgical treatment options have been suggested for this potentially malignant disorder (Arakeri and Brennan, 2013). While the role of physiotherapy has been highlighted in the conservative management, its importance in postsurgical cases to avoid scar contracture and subsequent relapse has not been given due importance in the literature. The following is a case report of a male patient surgically treated for OSMF (oral submucous fibrosis) and meticulously followed up for recalls and physiotherapy. The constant supervision and motivation for physiotherapy along with the constant assistance helped achieve satisfying results.

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