Prospective Memory Assessed by the Virtual Week in Older Adults With HIV

2021 ◽  
Vol 75 (Supplement_2) ◽  
pp. 7512505122p1-7512505122p1
Author(s):  
Yves Carlo Pinpin ◽  
Erin Foster ◽  
Beau M. Ances

Abstract Date Presented 04/21/21 Prospective memory (PM) impairment is common and limits daily function among individuals with HIV. We investigated PM and the relationships between PM, clinical characteristics, and cognitive test performance among older adults with HIV. Time-based PM tasks are problematic in this population potentially due to their memory and executive function demands. Thus, OT practitioners should implement compensatory strategies based on event-based PM to increase participation in meaningful activities. Primary Author and Speaker: Yves Carlo Pinpin

2020 ◽  
Vol 34 (3) ◽  
pp. 198-205 ◽  
Author(s):  
Fabian W. Corlier ◽  
Crystal Shaw ◽  
Eleanor Hayes-Larson ◽  
Dan Mungas ◽  
Sarah Tomaszewski Farias ◽  
...  

2017 ◽  
Vol 23 (8) ◽  
pp. 700-705 ◽  
Author(s):  
Lisa Manderino ◽  
Ian Carroll ◽  
M. Andrea Azcarate-Peril ◽  
Amber Rochette ◽  
Leslie Heinberg ◽  
...  

AbstractObjectives: Dysbiosis of the gut microbiome is implicated in numerous human health conditions. Animal studies have linked microbiome disruption to changes in cognitive functioning, although no study has examined this possibility in neurologically healthy older adults. Methods: Participants were 43 community-dwelling older adults (50–85 years) that completed a brief cognitive test battery and provided stool samples for gut microbiome sequencing. Participants performing≥1 SD below normative performance on two or more tests were compared to persons with one or fewer impaired scores. Results: Mann Whitney U tests revealed different distributions of Bacteroidetes (p=.01), Firmicutes (p=.02), Proteobacteria (p=.04), and Verrucomicrobia (p=.003) between Intact and Impaired groups. These phyla were significantly correlated with cognitive test performances, particularly Verrucomicrobia and attention/executive function measures. Conclusions: The current findings suggest that composition of the gut microbiome is associated with cognitive test performance in neurologically healthy older adults. Future studies are needed to confirm these findings and explore possible mechanisms. (JINS, 2017, 23, 700–705)


2015 ◽  
Vol 21 (2) ◽  
pp. 156-168 ◽  
Author(s):  
Cynthia A. Honan ◽  
Rhonda F. Brown ◽  
Jennifer Batchelor

AbstractPerceived cognitive difficulties and cognitive impairment are important determinants of employment in people with multiple sclerosis (pwMS). However, it is not clear how they are related to adverse work outcomes and whether the relationship is influenced by depressive symptoms. Thus, this study examined perceived and actual general cognitive and prospective memory function, and cognitive appraisal accuracy, in relation to adverse work outcomes. The possible mediating and/or moderating role of depression was also examined. A cross-sectional community-based sample of 111 participants (33 males, 78 females) completed the Multiple Sclerosis Work Difficulties Questionnaire (MSWDQ), Beck Depression Inventory – Fast Screen (BDI-FS), and questions related to their current or past employment. They then underwent cognitive testing using the Screening Examination for Cognitive Impairment, Auditory Consonant Trigrams test, Zoo Map Test, and Cambridge Prospective Memory Test. Perceived general cognitive and prospective memory difficulties in the workplace and performance on the respective cognitive tests were found to predict unemployment and reduced work hours since MS diagnosis due to MS. Depression was also related to reduced work hours, but it did not explain the relationship between perceived cognitive difficulties and the work outcomes. Nor was it related to cognitive test performance. The results highlight a need to address the perceptions of cognitive difficulties together with cognitive impairment and levels of depression in vocational rehabilitation programs in pwMS. (JINS, 2015,21, 156–168)


2007 ◽  
Vol 3 (3S_Part_2) ◽  
pp. S134-S134
Author(s):  
Patricia C. Heyn ◽  
Rosa A. Tang ◽  
Tammie Nakamura ◽  
Robert S. Schwartz

2019 ◽  
Vol 15 ◽  
pp. P1178-P1179
Author(s):  
Megan Zuelsdorff ◽  
Barbara B. Bendlin ◽  
Ozioma C. Okonkwo ◽  
Kate E. Sprecher ◽  
Lindsay R. Clark ◽  
...  

2020 ◽  
Vol 75 (12) ◽  
pp. 2239-2248 ◽  
Author(s):  
Florian Lammers ◽  
Norman Zacharias ◽  
Friedrich Borchers ◽  
Rudolf Mörgeli ◽  
Claudia Doris Spies ◽  
...  

Abstract Frailty is a geriatric syndrome defined by coexistence of unintentional weight loss, low physical reserve, or activity and is associated with adverse health events. Neuroimaging studies reported structural white matter changes in frail patients. In the current study, we hypothesized that clinical frailty is associated also with functional changes in motion-related cortical areas, that is, (pre-)supplementary motor areas (SMA, pre-SMA). We expected that observed functional changes are related to motor-cognitive test performance. We studied a clinical sample of 143 cognitively healthy patients ≥65 years presenting for elective surgery, enrolled in the BioCog prospective multicentric cohort study on postoperative cognitive disorders. Participants underwent preoperative resting-state functional magnetic resonance imaging, motor-cognitive testing, and assessment of Fried’s modified frailty criteria. We analyzed functional connectivity associations with frailty and motor-cognitive test performance. Clinically robust patients (N = 60) showed higher connectivity in the SMA network compared to frail (N = 13) and prefrail (N = 70) patients. No changes were found in the pre-SMA network. SMA connectivity correlated with motor speed (Trail-Making-Test A) and manual dexterity (Grooved Pegboard Test). Our results suggest that diminished functional connectivity of the SMA is an early correlate of functional decline in the older adults . The SMA may serve as a potential treatment target in frailty.


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