scholarly journals Association of serum sialic acid concentration with diabetic complications and cardiovascular risk factors in an Indian population

2021 ◽  
Vol 6 (1) ◽  
pp. 14-17
Author(s):  
Pankaj Bansal ◽  
Puja Bansal ◽  
Rajesh Verma
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Sialic Acid ◽  
Cardiovascular Risk Factors ◽  
Acid Concentration ◽  
Diabetic Complications ◽  
Indian Population ◽  
Serum Sialic Acid

scholarly journals Risk of cardiovascular disease among diabetic patients in rural population of Central India

2017 ◽  
Vol 5 (4) ◽  
pp. 1563
Author(s):  
Prem S. Singh ◽  
K. S. Zafar ◽  
Manoj Kumar ◽  
Sudhir K. Yadav
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Cardiovascular Diseases ◽  
Cardiovascular Risk Factors ◽  
Indian Population ◽  
Central India ◽  
Diabetic Patients ◽  
Intensive Management ◽  
Atherosclerotic Cardiovascular Diseases

Background: Incidence and prevalence of diabetes is on surge day by day and increased longevity of diabetic patients put them at higher risk of chronic complications of hyperglycemia. Of these complications, atherosclerotic cardiovascular diseases (CVD) are of utmost importance and atherosclerotic cardiovascular diseases are the major cause of premature mortality in patients with type 2 diabetes as well. Regional variation of risk factors and sociocultural diversity of Indian population create a significant difference in atherosclerotic risk among the diabetic population across the country. There is a significant gap in the knowledge of CVD epidemiology and associated risk factors among the Indian population especially among the rural population. The objective of this study was to assess cardiovascular risk among diabetic patients of rural central India.Methods: The present cross-sectional study included 160 diabetic patients (78 males and 82 females) aged 35–75 years from the villages of district Etawah of UP, Central India. Sex-specific Framingham general cardiovascular risk prediction equations were used to calculate the 10years risk for cardiovascular disease. The probable risk factors were determined by cross-tabulation of cardiometabolic parameters with the 10-year cardiovascular risk level.Results: Males were found to be at higher risk of developing CVD in the future as compared to females with a discernible accumulation of adverse cardiovascular risk factors among them. 38.75% patients were at high risk, 37.50% at moderate risk and 23.75% at low risk for developing CVD in the next 10 years. Systolic blood pressure, total cholesterol, triglyceride and smoking contributed significantly to high degree of cardiovascular risk. Presence of cardiovascular risk factors among diabetic patients at diagnosis accentuates the need of intensive management of cardiovascular complications taking into consideration the traditional dietary pattern of the rural population.Conclusions: Both diabetes and CVD have common genetic and environmental antecedents. Furthermore, insulin resistance preceding long before the diagnosis of diabetes enhances atherogenic risk profile and has been delineated as a potential cause for subsequent increased risk of CVD among diabetic patients. There is need of intensive management of cardiovascular risk factors among diabetic individuals. Therefore, there is a need of a comprehensive study design which includes various factors (biological, sociodemographic and genetic) which directly or indirectly influence the disease incidence especially in a country (India) with diverse ethnic population.

scholarly journals A study to derive distribution of CIMT and to determine its correlation with cardiovascular risk factors in asymptomatic nationwide Indian population

2015 ◽  
Vol 67 ◽  
pp. S114
Author(s):  
R.R. Kasliwal ◽  
Manish Bansal ◽  
Naresh Trehan ◽  
Nagaraj Desai ◽  
Bhavesh Kotak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Indian Population

PW199 Waist to height ratio and cardiovascular risk factors in a large representative North Indian Population

Global Heart ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e297
Author(s):  
Dorothy Lall ◽  
Pradeep A. Praveen ◽  
Ritvik Amarchand ◽  
Ruby Gupta ◽  
Ambuj Roy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Indian Population ◽  
North Indian Population ◽  
Height Ratio ◽  
Waist To Height Ratio ◽  
Large Representative

scholarly journals Serum Sialic Acid Concentration and Atherosclerotic Risk Factors

1994 ◽  
Vol 1 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Ichiro Wakabayashi ◽  
Kunihiro Sakamoto ◽  
Sachiko Yoshimoto ◽  
Eizo Kakishita
Keyword(s):  
Risk Factors ◽  
Sialic Acid ◽  
Acid Concentration ◽  
Serum Sialic Acid ◽  
Atherosclerotic Risk Factors

Serum sialic acid concentration in patients with hypertriglyceridaemia showing the Frederickson's IIB phenotype

1992 ◽  
Vol 83 (5) ◽  
pp. 593-595 ◽  
Author(s):  
M. Crook ◽  
P. Tutt
Keyword(s):  
Cardiovascular Risk ◽  
Sialic Acid ◽  
Normal Control ◽  
Acid Concentration ◽  
Serum Lipid ◽  
Total Serum ◽  
Control Group ◽  
Total Sialic Acid ◽  
Triacylglycerol Concentration ◽  
Serum Sialic Acid

1. Serum total sialic acid concentration, recently shown to be a cardiovascular risk factor, and also serum lipid-associated sialic acid concentration were measured in 15 patients with hypertriglyceridaemia (fasting serum triacylglycerol concentration > 2.3 mmol/l) showing a Frederickson's type IIB phenotype, 15 patients with hypercholesterolaemia showing a IIA phenotype and 15 age- and sex-matched normal control subjects. 2. Total serum sialic acid concentration was significantly raised in the hypertriglyceridaemic group (84.9 ± 21.5 versus 64.9 ± 20.8 mg/dl, P<0.03, Mann—Whitney U-test) compared with the normal control group, as was serum lipid-associated sialic acid concentration (23.0 ± 4.3 versus 12.0 ± 3.2 mg/dl, respectively, P<0.001, Mann—Whitney U-test). 3. Serum total sialic acid concentration was also significantly elevated in the hypertriglyceridaemic group as compared with the IIA phenotype hypercholesterolaemic group (84.9 ± 21.5 versus 58.4 ± 11.7 mg/dl, P<0.03, Mann—Whitney U-test), as was serum lipid-associated sialic acid concentration (23.0 ± 4.3 versus 14.9 ± 4.7 mg/dl, P<0.001, Mann—Whitney U-test). 4. We suggest that serum concentrations of both total sialic acid and lipid-associated sialic acid may be useful markers of cardiovascular risk which could, in part, be related to hypertriglyceridaemia.

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