scholarly journals N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDES IN INFANTS AND CHILDREN WITH NON-CARDIAC DISEASES

2021 ◽  
Vol 71 (3) ◽  
pp. 840-43
Author(s):  
Humaira Ali ◽  
Junaid M Alam ◽  
Shazia Naureen

Objective: To evaluate the levels of N-terminal pro-B-type Natriuretic Peptide in infants and children with non-cardiac diseases especially respiratory diseases. Study Design: Cross-sectional study. Place and Duration of Study: Department of Chemical Pathology/Biochemistry Laboratory Services of Liaquat National Hospital Karachi Pakistan, from Dec 2018 to Nov 2019. Methodology: Infants and children admitted to the Pediatric department with non-cardiac diseases were included in the study. Non-probability consecutive sampling was done. Blood was taken and analyzed for N- terminal pro-B-type Natriuretic Peptide, Troponin I, urea, creatinine, Lactate dehydrogenase, Creatinine Kinase, lactate and sodium analysis. Results: Out of the 93 patients, 74 (80%) were diagnosed with respiratory disorders, with bronchopneumonia making up 54 (59%) Bronchiolitis 15 (17%) and 4% had miscellaneous respiratory diseases. Out of the remaining 20%, 8 (9%) patients were diagnosed with sepsis, and the remaining 11% were diagnosed with miscellaneous diseases. There was a positive correlation of N- terminal pro-B-type Natriuretic Peptide with Troponin I, urea, creatinine, Creatinine Kinase and Lactate dehydrogenase levels (p<0.05). Conclusion: N- terminal pro-B-type Natriuretic Peptide levels were found to be raised in pediatric patients with non-cardiac diseases especially broncho-pneumonia and in future it may be used as a marker of bronchopneumonia in children.

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Abolhassan Seyezadeh ◽  
Mohamad Reza Tohidi ◽  
Mehdi Sameni ◽  
Mohammad Saleh Seyedzadeh ◽  
Sara Hookari

Background: Urinary tract infection (UTI) is the second most common infection in children. Parents’ lack of awareness and information about UTIs ultimately leads to delayed referral for treatment, which raises many concerns in parents. Objectives: The research aimed to evaluate the parental awareness of UTIs in infants and children and related demographic factors. Methods: In this cross-sectional analytical study, 270 parents who had a child or infant with UTIs referring to the Nephrology Clinic of Mohammad Kermanshahi Hospital in Kermanshah, Iran, in 2018 were selected by a convenience sampling method. To analyze the data, the chi-square test and Fisher's exact test were used. Results: According to the results, the parental awareness of the symptoms of UTIs in children was moderate, and the overall score on the awareness of complications, treatment, prevention, and diagnosis of UTIs in children was high. There were statistically significant relationships between the parental age and knowledge of UTI treatment in children, between paternal education and treatment and diagnosis and the total score of knowledge on UTIs in children, and between maternal education and awareness of the symptoms and how to prevent UTIs. Further, there was a statistical relationship between the children’s history of UTIs and the awareness of how to diagnose and treat UTIs in children (P < 0.05). Conclusions: Given the results, educational programs must be promoted to raise parents' awareness of UTIs in infants and children, especially UTI symptoms in lower educated, elderly parents whose other children have not had any history of UTIs.


2017 ◽  
Vol 53 (4) ◽  
pp. 740-747 ◽  
Author(s):  
Sonia Khirani ◽  
Alessandro Amaddeo ◽  
Naziha Khen-Dunlop ◽  
Jorge Olmo Arroyo ◽  
Alexandre Lapillonne ◽  
...  

1990 ◽  
Vol 20 (3) ◽  
pp. 358 ◽  
Author(s):  
Ho Seong Kim ◽  
Jin Young Lee ◽  
Jun Hee Sul ◽  
Sung Kyu Lee ◽  
Dong Shik Chin

2020 ◽  
Author(s):  
Mada Osefori ◽  
Leen Jamel Doya ◽  
Bana Nezha ◽  
Adnan Dayoub

Abstract Background: Transient tachypnea of the newborn(TTNB) is a common cause of respiratory distress in the postnatal period. It is rarely associated with serious complications that need intensive care. Prediction of the complications during the first hours of hospitalization is very difficult, so the purpose of the current study is to investigate the relationship between lactate dehydrogenase (LDH) level in blood and the course of Transient tachypnea of the newborn (the duration of hospitalization, and the incidence of complications).Material and methods: In a cross-sectional study design included 120 neonates with Transient tachypnea of the newborn who had referred to the Neonatal Intensive Care Unit (NICU) at Tishreen University Hospital over 1 year period from January 2018 to January 2019. The neonates were classified according to Lactate dehydrogenase measurement as normal or high lactate dehydrogenase level in blood.Results: The results showed that there was a significant relationship between the level of lactate dehydrogenase and the duration of hospitalization, the incidence of complications, and the frequency of complications.Conclusions: lactate dehydrogenase might be useful for clinicians to predict the duration of hospitalization and the incidence of complications in neonates with TTNB.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Diana Linhares ◽  
Patrícia Ventura Garcia ◽  
Fátima Viveiros ◽  
Teresa Ferreira ◽  
Armindo dos Santos Rodrigues

The aim of this study was to assess whether chronic exposure to volcanogenic air pollution by hydrothermal soil diffuse degassing is associated with respiratory defects in humans. This study was carried in the archipelago of the Azores, an area with active volcanism located in the Atlantic Ocean where Eurasian, African, and American lithospheric plates meet. A cross-sectional study was performed on a study group of 146 individuals inhabiting an area where volcanic activity is marked by active fumarolic fields and soil degassing (hydrothermal area) and a reference group of 359 individuals inhabiting an area without these secondary manifestations of volcanism (nonhydrothermal area). Odds ratio (OR) and 95% confidence intervals (CIs) were adjusted for age, gender, fatigue, asthma, and smoking. The OR for restrictive defects and for exacerbation of obstructive defects (COPD) in the hydrothermal area was 4.4 (95% CI 1.78–10.69) and 3.2 (95% CI 1.82–5.58), respectively. Increased prevalence of restrictions and all COPD severity ranks (mild, moderate, and severe) was observed in the population from the hydrothermal area. These findings may assist health officials in advising and keeping up with these populations to prevent and minimize the risk of respiratory diseases.


1988 ◽  
Vol 9 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Katarina Hanséus ◽  
Gudrun Björkhem ◽  
Nils-Rune Lundström

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