scholarly journals Acidosis Frequency in Children of Pediatric Acute Diarrhea

Esculapio ◽  
2021 ◽  
Vol 16 (4 (oct 2020 - dec 2020)) ◽  
Author(s):  
Muhammad Zain Ul Abadin ◽  
Arif Zaheer ◽  
Shahla Tariq ◽  
Muhammad Ans ◽  
Kashif Mehmood ◽  
...  
Keyword(s):  
Informed Consent ◽  
Key Words ◽  
Acute Diarrhea ◽  
Acid Base ◽  
Exclusion Criteria ◽  
Hospital Laboratory ◽  
Increase With Increase ◽  
Incidence Increase ◽  
Normal Acid ◽  
Arterial Sample

Objectives: To Found out the frequency of aidosis in patients of paediatric accute diarrhea. Methods: Two hundred and eighty children fulfilling the inclusion/exclusion criteria admitted in Department of Paediatrics, Services Hospital, Lahore was taken. Informed consent of the parents of children was obtained to include their data in the study. Every children with acute diarrhea was followed through 1-2cc arterial sample sent to the hospital laboratory of the hospital. Results: out of the total 280 patients, 83(29.5%) had acid base abnormality and 197(70.5%) had normal acid base imbalance. Out of 83(29.5%) patients who had acid base abnormality 50(17.5%) males and 22(8%) females had acidosis while only 8(3%) males and 3(1%) females had alkalosis. Conclusion: Acidosis is the most common abnormalities. Its incidence increase with increase in duration of diarrhea. Key Words: Acidosis, paediatric acute diarrhea How to Cite: Zain-ul-Abadin M, Zaheer A, Tariq S, Ans M, Mehmood K, Farooq M. Acidosis Frequency in Children of Pediatric Acute Diarrhea. Esculapio.2020;16(04):14-17.

Normal acid/base behaviour in proton transfer reactions to alkoxy substituted carbenes: estimates for intrinsic barriers to reaction and pKa values

1999 ◽  
Vol 77 (7) ◽  
pp. 1230-1240 ◽  
Author(s):  
John Paul Pezacki
Keyword(s):  
Proton Transfer ◽  
Key Words ◽  
Marcus Theory ◽  
Transfer Reactions ◽  
Acid Base ◽  
Pka Values ◽  
Proton Transfer Reactions ◽  
Normal Acid

Theoretical Eigen curves can be drawn through Brønsted data for dimethoxycarbene (1), phenyltrimethyl-siloxycarbene (3a), 4-methylphenyl(trimethylsiloxy)carbene (3b), 4-methoxyphenyl(trimethylsiloxy)carbene (3c), and β-naphthyl(trimethylsiloxy)carbene (3d). The Brønsted plots for these data are clearly curved with α values near 1 when proton transfer is thermodynamically unfavourable and α values near 0 when proton transfer is thermodynamically favourable, suggesting that these carbenes behave as "normal" Brønsted bases. Estimates of the intrinsic barriers (ΔG0‡) for proton transfer reactions and of the pKa values for the conjugate acids of the carbenes, extracted from these theoretical curves, have been made. The magnitudes of the intrinsic barriers (ΔG0‡) for these proton transfer reactions determined by Eigen and Marcus theories are all 1-5 kcal mol-1, suggesting that these reactions are intrinsically fast. Small intrinsic barriers also imply "normal" acid/base behaviour. Extrapolated pKa values are also the first estimates for the pKa values of the conjugate acids of carbenes 1 and 3a-3d. Key words: carbenes, proton transfer reactions, carbocations, Marcus theory, Brønsted plots.

scholarly journals Status Asthmaticus

2017 ◽  
Vol 15 (9-10) ◽  
pp. 269
Author(s):  
J.S Partana
Keyword(s):  
Body Weight ◽  
Status Asthmaticus ◽  
Fluid Administration ◽  
Acid Base Balance ◽  
Acid Base ◽  
Extreme Caution ◽  
Electrolyte Disturbances ◽  
Oxygen Administration ◽  
Base Balance ◽  
Normal Acid

The therapy of status asthmaticus must be rational. Thus it is important to evaluate: 1. the severity and duration of an asthmatic attack. 2. the degree of dehydration. 3. whether infection plays a role. 4. all medication previously administered. 5. any possible complication.Treatment is as follows :Fluid and electrolyte therapy is important not only for the correction of dehydration and electrolyte disturbances but also for preventing inspissation of mucus in the bronchi. The best route of fluid administration is intravenous.Potassium iodide orally administered may be helpful as an expectorant.After hydration and normal acid-base balance have been established, epinephrine may be of benefit.Aminophylline is effective when administered intravenously. It should be used with extreme caution: the dose should not exceed 3 mg per kg of body weight, it should be given slowly and should not be given more frequently than every 8 hours.Corticosteroids should be administered, especially in cases who have received suppressive doses previously.Humidified oxygen administration is of the utmost importance.Antibiotics are recommended when infection is suspected.Management of complications.

Renal function and acid-base balance in the toad Bufo marinus during short-term dehydration

1986 ◽  
Vol 64 (5) ◽  
pp. 1054-1057 ◽  
Author(s):  
B. L. Tufts ◽  
D. P. Toews
Keyword(s):  
Renal Function ◽  
Bufo Marinus ◽  
Ambient Water ◽  
Acid Base Balance ◽  
Acid Base ◽  
Short Term ◽  
Base Balance ◽  
Toad Bufo ◽  
Normal Acid ◽  
Tubular Component

Specimens of Bufo marinus (L.) were cannulated in both ureters to partition between the regulatory contributions of the kidney and urinary bladder. These bladder-bypassed animals were then exposed to 10 h of dehydration in air and renal function and acid–base balance were assessed. The results indicated that the kidney showed an almost immediate response to dehydration which consisted of a large glomerular and smaller tubular component. Bypassing and emptying of the bladder and the removal of the ambient water had no effect on the animal's ability to maintain normal acid–base balance.

ERRATA

PEDIATRICS ◽  
1980 ◽  
Vol 65 (5) ◽  
pp. 1006-1006
Keyword(s):  
Metabolic Acidosis ◽  
Diagnostic Approach ◽  
Acid Base ◽  
Arterial Blood ◽  
Blood Ph ◽  
P 351 ◽  
Normal Acid

In the article "A Diagnostic Approach to Metabolic Acidosis in Children" by Kappy and Morrow (Pediatrics 65:351-356, 1980) on p 351 under "Normal Acid-Base Physiology" the normal arterial blood pH is maintained at 7.40 (H+ = 39.8 nEq/liter not mEq/liter.

Normal Acid-Base Balance

2010 ◽  
pp. 149-154 ◽  
Author(s):  
Biff F. Palmer ◽  
Robert J. Alpern
Keyword(s):  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
Normal Acid
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