Diagnostic and therapeutic approach to esthesioneuroblastoma: case report

Esthesioneuroblastoma is a rare neoplasm of the nervous system that appears in the paranasal cavities derived from the olfactory neuroepithelium, located in the cribriform region of the nasal fossa, and can invade the sinuses of the face, skull base and orbital region. Kadish classification is the most widely used to stage it according to its extension. The symptomatology is unspecific, and it may present progressive unilateral nasal obstruction, epistaxis, anosmia, headache, sinusitis, diplopia, and orbital proptosis. The diagnosis is based on the lesion biopsy, immunohistochemistry, and ultrastructural findings. Excision of the tumor is described as the treatment of choice that may be associated with radiotherapy and chemotherapy. This is a case report of an olfactory esthesioneuroblastoma in a patient admitted to the hospital complaining of orbital proptosis who, after a computed tomography of the skull, showed a suspicious lesion. After the biopsy and the anatomopathological study, a protocol with neoadjuvant chemotherapy was initiated, with the subsequent excision of the tumor. Despite the lack of other symptoms, an advanced stage of the neoplasm was identified, which reflects the importance of investigating less common complaints and thus facilitating the diagnosis and early treatment.

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Bilateral Sturge Weber Syndrome- a rare case report

Nepalese Journal of Ophthalmology ◽

10.3126/nepjoph.v5i1.7841 ◽

2013 ◽

Vol 5 (1) ◽

pp. 129-132 ◽

Cited By ~ 1

Author(s):

P Singh ◽

S Singh

Keyword(s):

Case Report ◽

Rare Case ◽

Unusual Case ◽

The Other ◽

Advanced Stage ◽

Weber Syndrome ◽

Rare Case Report ◽

The Face ◽

Bilateral Condition ◽

Sturge Weber Syndrome

Background: Sturge-Weber syndrome is a rare congenital neuro- oculo- cutaneous disorder. Objective: To report a very rare unusual case of bilateral manifestation of Sturge Weber syndrome. Case: We report an unusual case of a 17-year-old female with advanced stage of bilateral glaucoma associated with facial nevus extending to the other half of the face as well and bilateral intracranial calcification. Conclusion: Sturge -Weber syndrome can manifest as a bilateral condition. Nepal J Ophthalmol 2013; 5(9):129-132 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7841

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Masson’s tumor of the pineal region: case report

Journal of Neurosurgery ◽

10.3171/2017.2.jns162350 ◽

2018 ◽

Vol 128 (6) ◽

pp. 1725-1730 ◽

Cited By ~ 1

Author(s):

Lefko T. Charalambous ◽

Anirudh Penumaka ◽

Jordan M. Komisarow ◽

Amanda C. Hemmerich ◽

Thomas J. Cummings ◽

...

Keyword(s):

Nervous System ◽

Case Report ◽

Vascular Malformations ◽

Subcutaneous Tissue ◽

Pineal Region ◽

Vascular Tumors ◽

Intravascular Papillary Endothelial Hyperplasia ◽

Masson’S Tumor ◽

The Face ◽

Papillary Endothelial Hyperplasia

Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson’s tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and can easily be mistaken clinically, radiologically, and histologically for angiosarcoma, organizing hematoma, or other vascular malformations. IPEH accounts for roughly 2% of all vascular tumors and is extremely rare intracranially, with only 23 reported cases compared with more than 300 cases of IPEH occurring in the skin and subcutaneous tissue. To date, it has never been reported to occur in the pineal region. The authors report the case of a patient with an IPEH in the pineal region who underwent complex resection and experienced reversal of neurological symptoms.

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Intracerebral Hematoma Secondary to Lightning Stroke: Case Report and Review of the Literature

Neurosurgery ◽

10.1227/00006123-198505000-00020 ◽

1985 ◽

Vol 16 (5) ◽

pp. 686-688 ◽

Cited By ~ 31

Author(s):

Lowell D. Stanley ◽

Richard A. Suss

Keyword(s):

Computed Tomography ◽

Central Nervous System ◽

Nervous System ◽

Case Report ◽

Basal Ganglia ◽

Intracerebral Hematoma ◽

Review Of The Literature ◽

Lightning Stroke ◽

The Central Nervous System ◽

Stroke Case

Abstract A young boy sustained a lightning stroke to his head. He was rendered immediately unconscious and hemiplegic. Computed tomography revealed three discrete basal ganglia hematomas. This patient's management is discussed, and a review of lightning injuries to the central nervous system is presented.

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Regression of Tumor in the Pineal Gland after Exclusive Radiotherapy: Case Report

10.5327/1516-3180.569 ◽

2021 ◽

Author(s):

João Lucas Pordeus de Menezes ◽

João Victor Bezerra Ramos ◽

Louyse Jerônimo de Morais ◽

Maurus Marques de Almeida Holanda

Keyword(s):

Magnetic Resonance Imaging ◽

Computed Tomography ◽

Central Nervous System ◽

Nervous System ◽

Case Report ◽

Pineal Gland ◽

Germ Cell Tumors ◽

Pineal Region ◽

Resonance Imaging ◽

The Central Nervous System

Background: Brain tumors are the most common solid neoplasia and the main cause of death from malignancy in children. Germ cell tumors (GCT) of the central nervous system (CNS) are rare. In pediatrics, the main location is close to the pineal gland and germinomas are the most common intracranial GCTs. Objectives and Methods: To describe the case of a patient with a possible germinoma treated exclusively with radiotherapy. The case was studied and came from a referral hospital – João Pesssoa, PB. Results: Reports “impaired failure”, disorientation and headache. Computed tomography: Hydrocephalus and strong tumor suspicion in the pineal region. Alpha-fetoprotein (AFP) and beta-gonadotropin (betaHCG) measurements: Normal. Treatment can be based on radiotherapy or chemotherapy followed by radiotherapy. In this case, radiotherapy was performed at a dosage of 10 Gy, with control, after one month, by means of magnetic resonance imaging that revealed regression of the lesion. The treatment corroborated the hypothesis of a germinoma, which is extremely radiosensitive. However, the regression made it impossible to perform the anatomopathological exam for diagnostic conclusion. Conclusions: It can be seen, then, that primary CNG GCTs are part of a heterogeneous group of extremely rare lesions, with germinoma therapy still controversial. The case shows regression of a possible germinoma only with the use of radiotherapy.

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Transient Prealbumin- Associated Hyperthyroxinemia in TSH-Producing Pituitary Adenoma

Nuklearmedizin ◽

10.1055/s-0038-1629511 ◽

1990 ◽

Vol 29 (01) ◽

pp. 40-43 ◽

Cited By ~ 3

Author(s):

W. Langsteger ◽

P. Költringer ◽

P. Wakonig ◽

B. Eber ◽

M. Mokry ◽

...

Keyword(s):

Computed Tomography ◽

Case Report ◽

Pituitary Adenoma ◽

Thyroid Hormones ◽

Protein Binding ◽

Alpha Subunit ◽

Normal Range ◽

Thyroxine Binding Globulin ◽

Free Thyroid Hormones ◽

Transmission Computed Tomography

This case report describes a 38-year-old male who was hospitalized for further clarification of clinically mild hyperthyroidism. His increased total hormone levels, the elevated free thyroid hormones and the elevated basal TSH with blunted response to TRH strongly suggested a pituitary adenoma with inappropriate TSH incretion. Transmission computed tomography showed an intrasellar expansion, 16 mm in diameter. The neoplastic TSH production was confirmed by an elevated alpha-subunit and a raised molar alpha-sub/ATSH ratio. However, T4 distribution on prealbumin (PA, TTR), albumin (A) and thyroxine binding globulin (TBG) showed a clearly increased binding to PA (39%), indicating additional prealbumin-associated hyperthyroxinemia. The absolute values of PA, A and TBG were within the normal range. After removal of the TSH-producing adenoma, basal TSH, the free thyroid hormones and T4 binding to prealbumin returned to normal. Therefore, the prealbumin-associated hyperthyroxinemia had to be interpreted as a transitory phenomenon related to secondary hyperthyroidism (T4 shift from thyroxine binding globulin to prealbumin) rather than a genetically conditioned anomaly of protein binding.

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