RELAPSES OF PULMONARY TUBERCULOSIS: SOCIAL AND MEDICAL CHARACTERISTICS

2021 ◽  
pp. 87-90
Author(s):  
O. M. Kalechits ◽  
A. M. Skrahina ◽  
D. A. Klimuk ◽  
E. L. Bobrukevich ◽  
A. F. Belko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Diagnosis ◽  
Pulmonary Tuberculosis ◽  
Successful Treatment ◽  
Multidrug Resistant ◽  
Specific Process ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
The Social ◽  
Rehabilitation Measures

Currently, a new grouping of contingents is being developed that are registered at dispensary in anti- tuberculosis organizations, where a place will be reserved for patients with relapses of tuberculosis, taking into account data from social and medical characteristics, and complex rehabilitation measures. Objective of the study: to study the social and medical characteristics of patients with recurrent pulmonary tuberculosis and the possibility of early diagnosis and successful treatment of tuberculosis. The paper presents data from a study of social and medical characteristics of 460 patients with recurrent pulmonary tuberculosis. It is shown that the bulk of the contingents are persons who are not engaged in labor activities, with bad habits and numerous risk factors for the reactivation of a specific process in the lungs. Relapses of tuberculosis more often occur after patients are removed from dispensary registration (76.2 %) and less often during the period of being registered (23.8 %) in the form of infiltrative (80.0 %) and disseminated (12.2 %) processes (p < 0.001). Treatment was found to be successful in 42.4 % of patients with relapse of multidrug-resistant tuberculosis and in 81.0 % of patients with relapse of drug-sensitive tuberculosis (p < 0.001).

scholarly journals Risk Factors for Multidrug-Resistant Tuberculosis among Patients with Pulmonary Tuberculosis at the Central Chest Institute of Thailand

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139986 ◽  
Author(s):  
Charoen Chuchottaworn ◽  
Vipa Thanachartwet ◽  
Piamlarp Sangsayunh ◽  
Thu Zar Myint Than ◽  
Duangjai Sahassananda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

scholarly journals A Case-Control Study to Identify Community Venues Associated with Genetically-clustered, Multidrug-resistant Tuberculosis Disease in Lima, Peru

2018 ◽  
Vol 68 (9) ◽  
pp. 1547-1555
Author(s):  
David P Bui ◽  
Eyal Oren ◽  
Denise J Roe ◽  
Heidi E Brown ◽  
Robin B Harris ◽  
...  
Keyword(s):  
Graph Model ◽  
Multidrug Resistant ◽  
Random Graph Model ◽  
Tuberculosis Transmission ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Exponential Random Graph ◽  
The Social ◽  
Community Segregation ◽  
Tuberculosis Disease

Abstract Background The majority of tuberculosis transmission occurs in community settings. Our primary aim in this study was to assess the association between exposure to community venues and multidrug-resistant (MDR) tuberculosis. Our secondary aim was to describe the social networks of MDR tuberculosis cases and controls. Methods We recruited laboratory-confirmed MDR tuberculosis cases and community controls that were matched on age and sex. Whole-genome sequencing was used to identify genetically clustered cases. Venue tracing interviews (nonblinded) were conducted to enumerate community venues frequented by participants. Logistic regression was used to assess the association between MDR tuberculosis and person-time spent in community venues. A location-based social network was constructed, with respondents connected if they reported frequenting the same venue, and an exponential random graph model (ERGM) was fitted to model the network. Results We enrolled 59 cases and 65 controls. Participants reported 729 unique venues. The mean number of venues reported was similar in both groups (P = .92). Person-time in healthcare venues (adjusted odds ratio [aOR] = 1.67, P = .01), schools (aOR = 1.53, P &lt; .01), and transportation venues (aOR = 1.25, P = .03) was associated with MDR tuberculosis. Healthcare venues, markets, cinemas, and transportation venues were commonly shared among clustered cases. The ERGM indicated significant community segregation between cases and controls. Case networks were more densely connected. Conclusions Exposure to healthcare venues, schools, and transportation venues was associated with MDR tuberculosis. Intervention across the segregated network of case venues may be necessary to effectively stem transmission.

scholarly journals Multidrug-resistant tuberculosis in Belarus: the size of the problem and associated risk factors

2012 ◽  
Vol 91 (1) ◽  
pp. 36-45 ◽  
Author(s):  
Alena Skrahina ◽  
Henadz Hurevich ◽  
Aksana Zalutskaya ◽  
Evgeni Sahalchyk ◽  
Andrei Astrauko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Associated Risk Factors
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