scholarly journals Risk Factors for Multidrug-Resistant Tuberculosis among Patients with Pulmonary Tuberculosis at the Central Chest Institute of Thailand

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139986 ◽  
Author(s):  
Charoen Chuchottaworn ◽  
Vipa Thanachartwet ◽  
Piamlarp Sangsayunh ◽  
Thu Zar Myint Than ◽  
Duangjai Sahassananda ◽  
...  
2021 ◽  
pp. 87-90
Author(s):  
O. M. Kalechits ◽  
A. M. Skrahina ◽  
D. A. Klimuk ◽  
E. L. Bobrukevich ◽  
A. F. Belko ◽  
...  

Currently, a new grouping of contingents is being developed that are registered at dispensary in anti- tuberculosis organizations, where a place will be reserved for patients with relapses of tuberculosis, taking into account data from social and medical characteristics, and complex rehabilitation measures. Objective of the study: to study the social and medical characteristics of patients with recurrent pulmonary tuberculosis and the possibility of early diagnosis and successful treatment of tuberculosis. The paper presents data from a study of social and medical characteristics of 460 patients with recurrent pulmonary tuberculosis. It is shown that the bulk of the contingents are persons who are not engaged in labor activities, with bad habits and numerous risk factors for the reactivation of a specific process in the lungs. Relapses of tuberculosis more often occur after patients are removed from dispensary registration (76.2 %) and less often during the period of being registered (23.8 %) in the form of infiltrative (80.0 %) and disseminated (12.2 %) processes (p < 0.001). Treatment was found to be successful in 42.4 % of patients with relapse of multidrug-resistant tuberculosis and in 81.0 % of patients with relapse of drug-sensitive tuberculosis (p < 0.001).


2012 ◽  
Vol 91 (1) ◽  
pp. 36-45 ◽  
Author(s):  
Alena Skrahina ◽  
Henadz Hurevich ◽  
Aksana Zalutskaya ◽  
Evgeni Sahalchyk ◽  
Andrei Astrauko ◽  
...  

2020 ◽  
Vol 24 (1) ◽  
pp. 92-99 ◽  
Author(s):  
M. P. Chen ◽  
R. Miramontes ◽  
J. S. Kammerer

OBJECTIVE: To determine risk factors for multidrug-resistant tuberculosis (MDR-TB) and describe MDR-TB according to three characteristics: previous TB disease, recent transmission of MDR-TB, and reactivation of latent MDR-TB infection.SETTING and DESIGN: We used 2011–2016 surveillance data from the US National Tuberculosis Surveillance System and National Tuberculosis Genotyping Service and used logistic regression models to estimate risk factors associated with MDR-TB.RESULTS: A total of 615/45 209 (1.4%) cases were confirmed as MDR-TB; 111/615 (18%) reported previous TB disease; 41/615 (6.7%) were attributed to recent MDR-TB transmission; and 449/615 (73%) to reactivation. Only 12/41 (29%) patients with TB attributed to recent transmission were known to be contacts of someone with MDR-TB. For non-US-born patients, the adjusted odds ratios of having MDR-TB were 32.6 (95%CI 14.6–72.6) among those who were known to be contacts of someone with MDR-TB and 6.5 (95%CI 5.1–8.3) among those who had had previous TB disease.CONCLUSION: The majority of MDR-TB cases in the United States were associated with previous TB disease or reactivation of latent MDR-TB infection; only a small proportion of MDR-TB cases were associated with recent transmission.


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