Oral mucosal lesions in patients with pemphigus and pemphigoid skin diseases: a cross sectional study from southern India.

Objective:To assess the prevalence of oral mucosal lesions in patients with pemphigus and pemphigoid diseases from Southern India. Design and Methods: A cross-sectional hospital based study was conducted from August 2010 to July 2011. Patients with confirmed pemphigus and pemphigoid skin disease were selected and informed to participate in the study. Oral examination of all participants were done to document site and type of oral manifestation and diagnostic procedures such as histopathological and Immunofluorescence methods were performed to confirm the diagnosis. Demographic details such as age, gender and occupation were also documented. The results of the study were analyzed by SPSS software version 19.0 (Armonk, NY) and presented as descriptive statistics. Results: Sixty percent of the patients exhibited oral mucosal manifestations. A higher female (86.66%) predilection of autoimmune blistering disease was observed in the study. A slightly higher number of pemphigoid patients (53.33%, 16 out of 30) were reported than pemphigus (46.66%, 14 out of 30 cases). The most common subtypes of pemphigus is Pemphigus vulgaris 71% (10 out of 14) among pemphigus, and bullous pemphigoid 87.5%(14 out of 16) among pemphigoid. Buccal mucosa (92.85%) is the most common site in pemphigus patients, where as hard palate (12.5%) is mostly commonly reported site in pemphigoid patients. Initial involvement of oral tissue in disease process was observed in 78.57% of pemphigus, and 12.5% of pemphigoid patients. Conclusion: Oral mucosal lesions are more frequently associated in pemphigus patients. Oral mucosal lesions are the initial site of disease process in pemphigus patients. The significance of diagnosis of oral lesions at earlier stage of disease, specifically pemphigus may help in early intervention of disease and help to reduce the morbidity and mortality state. The study emphasizes multidisciplinary approach in diagnosis and management of both pemphigus and pemphigoid.

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Gambaran Kebiasaan Menyirih dan Lesi Mukosa Mulut pada Mahasiswa Papua Di Manado

e-GIGI ◽

10.35790/eg.1.2.2013.3204 ◽

2013 ◽

Vol 1 (2) ◽

Author(s):

Dame R. Marbun

Keyword(s):

Oral Submucous Fibrosis ◽

Sampling Technique ◽

Cross Sectional Study ◽

Driving Factor ◽

Sectional Study ◽

Cross Sectional ◽

Slaked Lime ◽

Oral Mucosal Lesions ◽

Submucous Fibrosis ◽

Mucosal Lesions

Kebiasaan menyirih telah dilakukan sejak dahulu kala di Indonesia, khususnya pada suku Papua. Banyak anggapan masyarakat bahwa menyirih dapat menguatkan gigi geligi dan menghambat terjadinya karies, namun dibalik dampak positif dari menyirih ini, ada juga dampak negatifnya berupa timbulnya lesi pada mukosa yang melapisi rongga mulut.Tujuan penelitian ini yaitu untuk memperoleh gambaran kebiasaan menyirih pada mahasiswa Papua di Kota Manado, mencakup: tujuan menyirih, bahan campuran menyirih, lamanya kebiasaan menyirih, frekuensi menyirih, dan faktor pendorong kebiasaan menyirih serta untuk mengetahui gambaran lesi mukosa mulut pada mahasiswa Papua di Kota Manado.Jenis penelitian ini yaitu penelitian desktiptif dengan pendekatan cross-sectional study. Teknik pengambilan sampel yang digunakan ialah total sampling dengan jumlah sampel 30 orang. Dari 30 subjek yang diperiksa, sebagian besar merupakan wanita, usia 17-27 tahun. Lamanya menyirih terbanyak 6-10 tahun, dengan frekuensi terbanyak 1-3 kali sehari, bahan campuran menyirih yang paling banyak digunakan ialah campuran sirih, pinang dan kapur. Faktor pendorong utama menyirih yakni karena keinginan sendiri, dimana tujuan menyirih terbanyak yakni agar gigi menjadi kuat dan sehat. Dari 30 subjek ada 29 orang (96,66%) memiliki lesi dalam rongga mulutnya. Lesi yang diduga sebagai Oral Submucous Fibrosis yakni sebanyak 90% dan lesi yang diduga sebagai Betel Chewers Mucosa sebanyak 6,66%.Kata kunci: Kebiasaan menyirih, lesi mukosa mulut, Oral Submucous Fibrosis, Betel Chewer’s MucosaABSTRACTBetel chewing as a habit has been done since a long time ago in Indonesia, especially in Papua. There are some public perceptions that betel chewing can strengthen teeth and prevent caries. But, behind the positive effect of betel chewing, there are negative effects too, such as the onset of lesions in the oral mucosa.The purpose of this research is to get an overview of betel chewing habit on Papuan students in Manado, including the purpose of betel chewing, the complete material of betel chewing, duration of betel chewing, frequency of betel chewing, the driving factor of betel chewing, and to get an overview on oral mucosal lesions on Papuan students in Manado.The type of this research is descriptive research with a cross - sectional study. The sampling technique is total sampling with a sample size of 30 people. The 30 examined subjects, mostly women with age ranging from 17-27 years. The most length of chewing from 6-10 years, with the highest frequency of chewing 1-3 times a day, the average mixture of betel commonly used is betel, areca nut and slaked lime. The major driving factor in betel chewing is their own desire and the most common purpose is to get a strong and healthy teeth. 29 of 30 subjects (96,66%) have lesions in the oral cavity. In 90% of the sample, expected as Oral Submucous Fibrosis and in 6,66% expected as Betel Chewer’s Mucosa.Keyword: Betel chewing habit, oral mucosal lesions, Oral Submucous Fibrosis, Betel Chewer’s Mucosa

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Manifestasi Penyakit Kulit pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Dr. Pirngadi Medan

Nommensen Journal of Medicine ◽

10.36655/njm.v6i2.242 ◽

2021 ◽

Vol 6 (2) ◽

pp. 65-67

Author(s):

Dione Larissa Simanjuntak

Keyword(s):

Diabetes Mellitus ◽

Skin Diseases ◽

Disease Process ◽

Cross Sectional Study ◽

Cross Sectional ◽

Diabetic Ulcer ◽

Skin Manifestations ◽

Chronic Hyperglycemia ◽

Steven Johnson Syndrome

Background: Diabetes mellitus (DM) is a metabolic group with characteristic hyperglycemia that occurs due toabnormal insulin secretion, insulin action, or both. DM is often called the silent killer because the patients knowthey has DM only after the patient experiencing complications and manifestations. It is estimated that 30-70% of DM patients experience skin manifestations during the disease process. The relationship between the appearance of skin manifestations with diabetes mellitus is not yet known, but it is suspected due to chronic hyperglycemia and abnormalities of the immune system.Objective: To determine skin diseases in patients with type 2 diabetes at General Hospital Dr. Pirngadi Medan.Methods: This research was a descriptive study with a cross-sectional study design conducted at Dr. GeneralHospital Pirngadi Medan. Data collection was carried out through 29 medical records of patients with diabetesmellitus from January 2018 to December 2018. Samples were selected by total sampling.Results: From 29 samples studied, there were six types of skin manifestations. The most common skinmanifestations are Diabetic Ulcer (62.07%), followed by Steven Johnson Syndrome and diabetic gangrene, which both are equally 13.80%. The other skin manifestations are herpes zoster, gluteal abscess, and bullous pemphigoid (3.44%).Conclusion: The most common manifestation of the skin in patients with type 2 DM is Diabetic Ulcer.

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Prevalence and distribution of oral mucosal lesions: a cross-sectional study in Shanghai, China

Journal of Oral Pathology and Medicine ◽

10.1111/jop.12264 ◽

2014 ◽

Vol 44 (7) ◽

pp. 490-494 ◽

Cited By ~ 21

Author(s):

Jinqiu Feng ◽

Zengtong Zhou ◽

Xuemin Shen ◽

Yufeng Wang ◽

Linjun Shi ◽

...

Keyword(s):

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Oral Mucosal Lesions ◽

Mucosal Lesions

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Comparison of Oral Mucosal Lesions and Gingival, Periodontal Indices among Pregnant and Non Pregnant Women-an Observational Cross-Sectional Study

Indian Journal of Public Health Research & Development ◽

10.5958/0976-5506.2015.00204.1 ◽

2015 ◽

Vol 6 (4) ◽

pp. 82

Author(s):

Prajna V Kini ◽

GP Mamatha ◽

Rajeshwari G Annigeri ◽

Vinod R Jathanna ◽

Vidhi Vinayak ◽

...

Keyword(s):

Pregnant Women ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Oral Mucosal Lesions ◽

Mucosal Lesions ◽

Periodontal Indices

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Oral mucosal lesions in a representative cross-sectional study of aging Germans

Community Dentistry And Oral Epidemiology ◽

10.1034/j.1600-0528.2000.028005390.x ◽

2000 ◽

Vol 28 (5) ◽

pp. 390-398 ◽

Cited By ~ 133

Author(s):

Peter A. Reichart

Keyword(s):

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Oral Mucosal Lesions ◽

Mucosal Lesions

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Oral mucosal lesions in teenagers: a cross-sectional study

Italian Journal of Pediatrics ◽

10.1186/s13052-017-0367-7 ◽

2017 ◽

Vol 43 (1) ◽

Cited By ~ 7

Author(s):

Francesca Amadori ◽

Elena Bardellini ◽

Giulio Conti ◽

Alessandra Majorana

Keyword(s):

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Oral Mucosal Lesions ◽

Mucosal Lesions

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Oral Mucosal Lesions in Turkish Adolescents Admitted to a Dermatology Outpatient Clinic-A Tertiary Hospital-Based Study: Cross-Sectional Study

Turkiye Klinikleri Journal of Dermatology ◽

10.5336/dermato.2021-86286 ◽

2021 ◽

Vol 31 (3) ◽

pp. 217-223

Author(s):

Atiye AKBAYRAK ◽

Tuba KASAP ◽

Zennure TAKÇI ◽

Havva YILDIZ SEÇKİN ◽

Osman DEMİR ◽

...

Keyword(s):

Outpatient Clinic ◽

Tertiary Hospital ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Oral Mucosal Lesions ◽

Mucosal Lesions

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Prevalence of Oral Mucosal Lesions and Their Association with Severity of Psoriasis among Psoriatic Patients Referred To Dermatology Clinic: A Cross-Sectional Study in Kashan/Iran

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2017.189 ◽

2017 ◽

Vol 5 (7) ◽

pp. 978-982 ◽

Cited By ~ 7

Author(s):

Rezvan Talaee ◽

Zohreh Hajheydari ◽

Ahmad Yeganeh Moghaddam ◽

Seyyed Alireza Moraveji ◽

Bentolhoda Fatahi Ravandi

Keyword(s):

Clinical Importance ◽

Severity Index ◽

Oral Lesion ◽

Cross Sectional Study ◽

Oral Lesions ◽

Cross Sectional ◽

Exact Test ◽

Dermatology Clinic ◽

Oral Mucosal Lesions ◽

Mucosal Lesions

BACKGROUND: Psoriasis is a common inflammatory papulosquamous disease of the skin with unknown aetiology that may be associated with the abnormal T-cell function.AIM: This study was aimed to determine the prevalence of oral mucosal lesions and their associations with severity of psoriasis in psoriatic patients attending the dermatologic clinic of Shahid Beheshti Teaching Hospital at Kashan, Iran.METHODS: In this cross-sectional descriptive analytic study, all consecutive patients with psoriasis who referred to the dermatologic clinic at the Shahid Beheshti Hospital of Kashan University of Medical Sciences in Kashan City/ Iran were enrolled. All patients were examined for the presence of oral lesions, and the clinical and epidemiological features of the disease were recorded in a questionnaire for each patient. A biopsy was taken from atypical suspected patients with oral lesions by an expert dermatologist. Data were analysed using the Statistical Package for Social Science (Version 18). Descriptive statistics tests; Cross tabulation and Chi-square with Fisher's exact test were used.RESULTS: Of total 177 psoriatic patients, 62 cases (35%) of patients were male, and 115 cases (65%) were female. Mean age of patients was 31.71 years. The oral lesion was seen in 83 cases (46.9%). Fissure tongue (28.2%) and geographic tongue (4.5%) were the most common oral lesions. The prevalence of oral lesions in patients with psoriasis significantly was associated with age, history of oral lesions, and with the onset of the oral lesions (P < 0.05). The most common form of psoriasis was chronic plaque form (Psoriasis Vulgaris) observed in 147 cases (83.1). The majority of patients (67.2%) were suffering from a mild form of the disease. Psoriasis Area and Severity Index (PASI) score of most patients was mild.CONCLUSIONS: The prevalence of oral lesions such as Fissure tongue and geographic tongue is higher in psoriatic patients suggests further studies for approving the clinical importance of these apparently nonspecific lesions as possible predictors or markers of the severity of the cases suspected to Psoriasis disease.

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