Occurrence of canine mammary and skin/ subcutaneous neoplasms in and around 	 	 Thrissur district of Kerala during 2017-2020: A review of 265 cases

The study was conducted in 265 clinical cases of mammary and skin/ subcutaneous neoplasms in dogs presented to University Veterinary Hospitals Mannuthy and Kokkalai during a period of 36 months from October 2017 to September 2020. Mammary neoplasms were found more in females (51.7 per cent) than in males whereas skin and subcutaneous neoplasms were found more in male dogs (48.3 per cent). The maximum occurrence of neoplasms was recorded in the age group of eight to twelve years (38.5 per cent) whereas least occurrence was noticed in the age group up to four years (9 per cent). Labrador and Rottweiler breeds were found more affected with neoplasms (38 per cent each) with highest occurrence of mammary neoplasms in inguinal mammary glands (35.03 per cent) and highest occurrence of skin/ subcutaneous neoplasms on sites involving trunk region (14.06 per cent cases). Eighty-three per cent of the neoplasm cases in the present study were pet dogs with a greater number of dogs maintained in outdoor kennels and 17 per cent of neoplasm was found in free-roaming dogs rescued from streets. Out of total 265 dogs, 37.73 per cent dogs were found to be having commercial dog food as their main feed and 32 per cent dogs were fed with a mixed diet of homemade food and commercial dog food. Among the cases, 14.71 per cent dogs had a previous history of cancer surgery

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The clinical study of the incisional hernia and its management

International Surgery Journal ◽

10.18203/2349-2902.isj20172781 ◽

2017 ◽

Vol 4 (7) ◽

pp. 2281

Author(s):

Navdeep Garg ◽

Pooja Batra ◽

Sharadendu Bali

Keyword(s):

Incisional Hernia ◽

Previous History ◽

Exploratory Laparotomy ◽

Suture Repair ◽

Age Group ◽

Common Complication ◽

Response Sets ◽

History Of ◽

Sublay Mesh ◽

Mesh Hernioplasty

Background: Hernia is defined as abnormal protrusion of viscus through a normal or abnormal weakness in the wall of its containing cavity. Incidence of Incisional hernias is 60%. It is the most common complication after exploratory laparotomy followed by LSCS.Methods: Data was collected for 30 cases of incisional hernia according to the proforma which included detailed history, clinical examination and investigation. Data was tabulated, analyzed and results interpreted.Results: Incisional hernia was more common in females with the ratio 1.5:1. The incidence of incisional hernia was highest in the age group ranging from 30-50 years. Most of the patients presented with chief complaint of swelling (100%) followed by pain and swelling (24%). Incisional hernia was more common in patients of previous history of abdominal procedures (explorative laparotomy 53%) followed by gynaecological operations (23%). Out of 30 patients studied, 20 underwent only mesh hernioplasty (67%), 10 underwent sublay mesh hernioplasty (23%).Conclusions: With prosthetic mesh, defects of any size can be repaired without tension. The polypropylene mesh, by inducing inflammatory response sets up scaffolding that in turn induces the synthesis of collagen. Thus, the superiority of mesh repair over suture repair can be accounted for.

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Association between red blood cell distribution width and long-term mortality among patients undergoing percutaneous coronary intervention with previous history of cancer

Biomarkers ◽

10.1080/1354750x.2020.1734860 ◽

2020 ◽

Vol 25 (3) ◽

pp. 260-267

Author(s):

Qing-Yong Yang ◽

Xiu-Feng Li ◽

Mao-Qiang Lin ◽

Jia-Hao Xu ◽

Han Yan ◽

...

Keyword(s):

Previous History ◽

Coronary Intervention ◽

Cell Distribution ◽

Distribution Width ◽

Percutaneous Coronary ◽

History Of ◽

Red Blood Cell Distribution ◽

History Of Cancer ◽

Long Term Mortality

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Never-smoking women with lung cancer from the Spanish WORLD07 database.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.15_suppl.1531 ◽

2012 ◽

Vol 30 (15_suppl) ◽

pp. 1531-1531 ◽

Cited By ~ 1

Author(s):

Dolores Isla ◽

Mariano Provencio ◽

Margarita Majem ◽

Enriqueta Felip ◽

Nuria Vinolas ◽

...

Keyword(s):

Lung Cancer ◽

Contraceptive Use ◽

Previous History ◽

Stage Iv ◽

Egfr Mutations ◽

Malignant Tumours ◽

Treatment Data ◽

History Of ◽

Egfr Tki ◽

History Of Cancer

1531 Background: Gender differences in lung cancer (LC) have been reported, but with many unresolved issues yet. Tobacco causes the majority of women lung cancer (WLC), although the rate of never-smoking WLC is higher than in men. Several factors may play etiologic roles, and an in-depth understanding is needed. Methods: WORLD07 is a Spanish prospective, multicenter, epidemiologic female-specific LC database sponsored by ICAPEM, a professional association committed with WLC research. In order to improve the knowledge on never-smoking WLC, information has been extracted from WORLD07 database. Results: From October/2007 to October/2011, 1371 newly diagnosed WLC were included in an e-database from 32 centers, 539 (39.3%) never-smoking. Patient (p) characteristics: median age 71.1 years(y); median age of menarche 13y.; motherhood 91.2% (median 2.3 children, median age at first child 26.4y); oral contraceptive use 11.9%; postmenopausal 88.9% (median age of menopause 49y); HRT 5.2%; second-hand smokers 40% (work-exposure 17.1%, home-exposure 88.8%); obesity 16.3%; familiar history of cancer 39.9% (LC 29.8%); previous history of cancer 13% (breast/lung/cervix: 41.4/5.7/2.9%); current LC histology(%): adenocarcinoma/SqCC/LCC/SCLC: 83.4/6.2/5.5/3.9; EGFR mut+ (268 p analyzed): 55.5% (exon 19/20/21(%): 61.1/7.4/36.9); TNM NSCLC I/II/III/IV(%): 14/3.3/19.8/60.3. Treatment: EGFR-TKI in p EGFR mut+, stage IV(1st-/2nd-line)(%): 51.7/15.4; stage IV NSCLC (1st-line/2nd-line): platinum-based CT 42.5%, EGFR-TKI 33.5%, combinations with bevacizumab 2.9% / EGFR-TKI 15.8%. Overall survival: median 27 months(m), 1/2-y(%) 74.8/55.2; stage IV NSCLC: median 20.5m, 1/2-y(%) 67/46; EGFR-mut+ p: median 27.3m, 1/2-y(%) 75/54.3. Conclusions: According to our e-database, WLC showed high rates of never-smokers (39.3%), and of relatives diagnosed with malignant tumours (39.9%, ≅1/3 LC). Adenocarcinoma was the most frequent histology (76.1%), and more than half of the cases analyzed harboured EGFR mutations. Although 40% were second-hand smokers, further investigations are warranted. Survival outcomes remain satisfactory, as expected from this selected subgroup of p. Additional epidemiologic and treatment data will be presented.

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Is cancer history associated with asset ownership, debt, and net worth in the United States?

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.e18085 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. e18085-e18085

Author(s):

Maryam Doroudi ◽

Diarmuid Coughlan ◽

Matthew P. Banegas ◽

K Robin Yabroff

Keyword(s):

United States ◽

Cancer Survivors ◽

The United States ◽

Medical Expenditure ◽

Age Group ◽

Asset Ownership ◽

Cancer History ◽

Net Worth ◽

History Of ◽

History Of Cancer

e18085 Background: Financial hardships experienced by cancer survivors in the United States have become significant social and public health issues. Few studies have assessed the underlying financial holdings, including ownership and values of assets and debts, of individuals following a cancer diagnosis. This study assessed the association between a cancer history and asset ownership, debt, and net worth. Methods: We identified 1,603 cancer survivors and 34,915 individuals without a history of cancer aged 18-64 from the nationally representative Medical Expenditure Panel Survey (MEPS) Household Component and Asset sections (years 2008-2011). Descriptive statistics were used to assess demographic characteristics, cancer history, asset ownership, debt, and net worth by cancer history. Regression analysis was conducted to assess the association between cancer history and net worth, stratified by age group (18-34, 35-44, 45-54, and 55-64 years) to reflect stages of the life-course. Results: Asset ownership was least common for cancer survivors and individuals without a cancer history in the 18-34 age group and most common in the 55-64 age group. Cancers survivors aged 45-54 had a lower proportion of home ownership than individuals without a cancer history (59% vs 67%; p = 0.001). Nearly 20% of all respondents reported at least some debt. The proportion of cancer survivors with debt was higher than individuals without a history of cancer, especially in the 18-34 age group (41% vs 27%; p < 0.001), although it did not vary by age group. When asset and debt values were combined to assess net worth, cancer survivors aged 45-54 were significantly more likely to have a negative net worth and significantly less likely to have a positive net worth than those individuals without a history of cancer in fully adjusted models. Findings on net worth were similar in the 18-34 age group, although only statistically significant in unadjusted and partially adjusted models. Conclusions: We found that cancer history is associated with asset ownership, debt, and net worth, especially in those aged 45-54 years. Longitudinal studies to assess patterns of financial holdings throughout the cancer experience are warranted.

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HYPOTHYROIDISM;

The Professional Medical Journal ◽

10.29309/tpmj/2017.24.01.417 ◽

2017 ◽

Vol 24 (01) ◽

pp. 36-41

Author(s):

Shafat Khatoon ◽

Aijaz Ahmed ◽

Nighat Jabeen ◽

Erum Rehman

Keyword(s):

Serum Lipids ◽

Previous History ◽

Young Patients ◽

P Value ◽

Age Group ◽

Active Life ◽

Group I ◽

History Of ◽

Hypothyroid Patients ◽

Significant Health

Cardiovascular diseases (CVDs) are the number one cause of death globally:more people die annually from CVDs than from any other cause. An estimated 17.5 millionpeople died from CVDs in 2012, representing 31% of all global deaths. Although CVDs areuncommon entity in young patients, it constitutes significant health problem due to itsdyslipidemia cases and devastating effects on active life style of young patients, it is thereforeimportant to identify diseases in young that are associated with or a cause of dyslipidemia1.Hypothyroidism is an important cause of dyslipidemia in young that can significantly increasethe risk of CVDs2. Objectives: This study is designed “to determine frequency of dyslipidemiain young hypothyroid patients”. Place and duration of Study: Study conducted at MedicalOPD JPMC, Karachi (outpatient) in six months duration from 25th May 2009 to 24th November2009. Patients and Methods: Study is performed on 100 newly diagnosed cases of primaryhypothyroidism between ages 25 to 55 years, non-smokers, having no previous history ofIschemic Heart Disease (IHD) or family history of premature CVD, diabetes mellitus (DM), hepaticor renal disease, not on drugs which could alter serum lipids. Selected case undergone 14hours fasting lipid profile check. Results: Out of 100 hypothyroid cases, 91% had dyslipidemiawhich was directly proportional to severity of hypothyroidism. Out of 100 hypothyroid cases,95 (95%) were of young age group i-e from 25-49 years, and all of them were dyslipidemic,while 05 (5%) hypothyroid patients were of age group more than 50 years and none of themhad dyslipidemia. (0.00%) and this distribution of dyslipidemic in young hypothyroid patientsis statistically significant (p value 0.031) Conclusion: Hypothyroidism is associated with highfrequency of dyslipidemia in young patients which significantly predisposes them to risks ofCVDs.

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