Comparison of Imprint Cytology and Frozen Section Techniques at Intraoperative Diagnosis: 381 Cases

1995 ◽  
Vol 5 (2) ◽  
pp. 157-163
Author(s):  
Muhan Erkuş ◽  
Süheyla Cumurcu ◽  
Aydın Şahin ◽  
Murat Cirik ◽  
Ümit Bayol
1970 ◽  
Vol 24 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Sukumar Shaha ◽  
AJE Nahar Rahman

 Imprint cytology can provide a useful adjunct to the frozen section diagnosis and may be used safely in the intraoperative diagnosis of thyroid nodules, especially in the centres where frozen section facilities are not available. This study was conducted to compare imprint cytology and frozen section in terms of diagnostic accuracy, sensitivity, specificity, positive predictive value and to assess the value of imprint cytology in the intraoperative diagnosis of thyroid lesions. A total of 57 consecutive patients were enrolled in the study. All of the patients underwent frozen section in the department of pathology, BSMMU, Dhaka. Imprints were taken from the fresh specimen sent for frozen section from departments of otolaryngology and surgery of BSMMU. Imprint slides were stained with rapid H & E staining method. Then the tissues were submitted for frozen section by standard method. In this study, diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive value of imprint cytology were 81.25%, 66.66%, 82.59%, 87.12% respectively. Frozen section revealed the diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive as 88.46%, 72.72%, 100%, 100%, 83.33% respectively. Imprint cytology was found to be comparable with frozen section in diagnostic accuracy and sensitivity. Since imprint cytology is a simple and cost-effective procedure it can be used as an alternative to frozen section in hospitals where frozen section facilities are not available. Key Words: Imprint cytology, frozen section, intraoperative diagnosis of thyroid lesions  doi: 10.3329/bjpath.v24i1.2876 Bangladesh J Pathol 24 (1) : 12-15   


Author(s):  
Reily Ann Ivan ◽  
Kuruvilla P. Chacko ◽  
Pramod Thomas

Background: The ovaries frequently are the site for various primary tumors. Correct intraoperative diagnosis is crucial. The application of imprint cytology is very useful where frozen section facility is not available. The present study is a comparison of imprint cytology and frozen section during intraoperative consultation for various types of benign and malignant ovarian neoplasms in different age groups.Methods: Seventy-six cases of ovarian tumors were examined using both imprint cytology and frozen section and evaluated, taking histopathological report as gold standard. The histopathological diagnoses consisted of benign (54), borderline (9), and malignant (13). The malignant tumors consisted of various types including serous carcinoma, mucinous carcinoma, endometrioid carcinoma, clear cell carcinoma and carcinoid.Results: All 54 benign cases were accurately diagnosed as benign by imprint cytology. With frozen section 53 cases were correctly diagnosed as benign but one case was over diagnosed as borderline. Among 13 malignant cases 11 (84.6%) were correctly diagnosed with both techniques. Borderline tumors were not able to be diagnosed with imprint smear, 3 out of 9 cases were correctly diagnosed with frozen section.Conclusion: When compared with frozen section, imprint cytology is a simple, inexpensive and useful diagnostic tool in intraoperative diagnosis of benign and malignant ovarian tumors. Imprint smear is not useful in borderline tumors where only frozen section is useful. Imprint cytology can be used as an adjunct to frozen section for better diagnosis.


1987 ◽  
Vol 88 (6) ◽  
pp. 681-688 ◽  
Author(s):  
Jose M. Esteban ◽  
Charles Zaloudek ◽  
Steven G. Silverberg

2017 ◽  
Vol Volume 9 ◽  
pp. 325-330 ◽  
Author(s):  
Thalia Petropoulou ◽  
Antonia Kapoula ◽  
Aikaterini Mastoraki ◽  
Aikaterini Politi ◽  
Eleni Spanidou-Karvouni ◽  
...  

2005 ◽  
Vol 129 (3) ◽  
pp. e65-e66 ◽  
Author(s):  
Kambridge P. Hribar ◽  
Nancy E. Warner ◽  
Andy E. Sherrod

Abstract Although not required for the diagnosis, crystalloids of Reinke are pathognomonic for Leydig cell tumor. However, conventional frozen section rarely reveals their presence. A method of rapid identification of crystalloids of Reinke could improve the intraoperative diagnosis. We tested the efficacy of touch imprints and scrape smears for the identification of crystalloids in 2 cases of Leydig cell tumor of the testis. Intraoperative smears of the tumors yielded abundant crystals. Scrape cytologic testing was the better method. We speculate that the process of scraping, and to a lesser extent touch imprinting, disrupts the cytoplasm of the Leydig cells and releases the crystalloids. We conclude that cytologic testing is an effective method of identifying crystalloids of Reinke in Leydig cell tumors of the testis.


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