scholarly journals OBSERVATION OF MORPHOLOGICAL CHANGES IN THE FETUS AND PLACENTA OF PREGNANT WOMEN INFECTED WITH CYTOMEGALOVIRUS THROUGH ULTRASOUND EXAMINATION

Author(s):  
TEIMURAZ LOMSIANIDZE

In 2008-2018, 89 pregnant women registered at the Beaumonde Clinic were observed with only cytomegalovirus activity. Laboratory tests for cytomegalovirus were performed 4 times in total, and ultrasound examination was performed 3 times during pregnancy. The results were distributed as follows: (1) We could have assumed with high probability that we had reinfection processes and not a primary infection. (2) During the ultrasound examinations, no significant organic disturbances in the development of the fetus were detected. (3) In all cases, various morphological changes were observed in the placenta, which are not specific for CMV and are found during any infectious process: premature aging of the placenta, increase in thickness and enhanced calcification. Degenerative changes in placental tissues increase the risk of perinatal loss. (4) As a result of childbirth, all newborns were born without visible pathology. However, this did not rule out latent disease and later detected pathologies.

2019 ◽  
Vol 23 (3) ◽  
pp. 283-289
Author(s):  
Y. A. Revzoeva ◽  
E. Y. Shakurova

The article defines the significance and relevance of the problem of endometriosis during pregnancy. 10% of women in the reproductive period have different localization of endometriosis. 25% of pregnancies with endometriosis are complicated by preterm labor. The article presents a clinical case of intra-abdominal bleeding in a 28-year-old pregnant woman with retrocervical endometriosis at gestation age of 32 weeks and 6 days. The article covers the results of examination and special diagnostic procedures of intra-abdominal bleeding in pregnant women with retrocervical endometriosis. The main diagnostic methods were the study of past medical history, ultrasound examination, and laboratory tests. Due to their infrequency during pregnancy internal bleedings present difficulties in their diagnosis. Ultrasound reliably revealed a large amount of fluid in the abdominal cavity and small pelvis and excluded the presence of intrauterine bleeding. Clinical and laboratory tests indicated the severity of the patient's condition. Symptoms of moderate fetal distress were also identified. Therefore, a decision was made about an emergency delivery by the cesarean section followed by an abdominal revision. During the cesarean section, 500 ml of blood in the form of dark blood clots was found in the abdominal cavity. The condition of the premature newborn was in conformity with his gestational age. The source of bleeding were the of endometriosis on the back wall of the uterus. These focuses most likely caused hemoperitoneum. The revision of the abdominal cavity did not find any other foci of bleeding. The postoperative period was uneventful. The article provides general guidelines for the management of pregnant women with severe forms of endometriosis.


2021 ◽  
pp. 10-15
Author(s):  
Volodymyr I. Chermak ◽  
Ihor I. Chermak ◽  
Chukwuanyinonso O. Ikeotuonye ◽  
Anatolii Ya. Senchuk

To study morphological features of the placenta in women in labor, pregnancy which complicated by preeclampsia we studied 26 placentae, of which 17 were from pregnant women with mild to moderate preeclampsia (basic group) and 9 from healthy women (control group). Histologically the study was conducted with methodically recommendations of T.D. Zadorozhnaya et al. for light microscopy. During the study of morphological features of the placenta in women in labor with preeclampsia were installed morphological changes in the placenta, which reflect a tendency to develop compensatory-adaptive reactions following their stress and exhaustion, which is a sign of placental insufficiency. Received data allow claiming a high frequency of development placental insufficiency in pregnant women with risk factors such as chronic salpingo-oophoritis, anemia, late preeclampsia, and inflammation diseases kidney.


2013 ◽  
Vol 62 (6) ◽  
pp. 47-54 ◽  
Author(s):  
Roza Nuraddinovna Rzaeva ◽  
Elena Vitalievna Mozgovaya ◽  
Ljudmila Konstantinovna Palgova ◽  
Valentina Mikchailovna Prokopenko ◽  
Zhanna Nikolaevna Tumasova

40 pregnant women with obesity were totally examined and their outcomes of pregnancy and delivery were controlled. The examination of all pregnant women included the comprehensive examination of the functional state of the hepatobiliary system, ultrasound examination of the liver to identify the liver steatosis. These medical examinations made possibility to assess the dynamics of a clinical picture, ultrasound conclusions, biochemical indicators of liver function and lipid metabolism during the treatment. The frequency and severity of obstetric complications were also assessed.


2020 ◽  
Vol 2020 (1) ◽  
pp. 1 ◽  
Author(s):  
Dan-Bogdan Navolan ◽  
Florin Gorun ◽  
Cristian Oancea ◽  
Ioana-Mihaela Ciohat ◽  
Daniel Malița ◽  
...  

(1) Background: Toxoplasma gondii and cytomegalovirus belong to a group of pathogens entities called TORCH agents. TORCH represents an acronym which derives from the name of a series of certain pathogenic agents (Toxoplasma gondii, Other agents, Rubella virus, Cytomegalovirus, Herpes virus). They could cross the placenta barrier and cause serious damage to the fetus if a primary infection occurs in a pregnant woman. Immunized women are relatively protected against a reinfection and the risk of a materno-fetal infection in these categories of pregnant women is considered low. (2) Aim of the study: To analyze changes in the percentage of pregnant women seronegative to Toxoplasma gondii and cytomegalovirus along a period of ten years, from 2008 to 2018. (3) Material and Methods: We studied the changes in percentage of seronegative Toxoplasma gondii and Cytomegalovirus pregnant women along two periods: 2008–2010 and 2015–2018. Only pregnant women with declared medium of provenience and unequivocal results were enrolled in the study. (4) Results: In urban areas, we found an increase in the percentage of pregnant women seronegative to Toxoplasma gondii (RR = 1.488, p < 0.0001), respectively to cytomegalovirus (RR = 1.985, p < 0.0001), from 2008–2010 to 2015–2018. A similar increasing trend was found also in rural areas: Toxoplasma gondii (RR = 1.136, p < 0.0322), respectively cytomegalovirus (RR = 1.088, p < 0.8265) but it did not reach a significant threshold for cytomegalovirus. (5) Conclusion: Our study showed that the percentage of women seronegative to Toxoplasma gondii and cytomegalovirus antibodies increases along a period of ten years, from 2008–2010 to 2015–2018, in both urban and rural areas. Probably, the main cause of this trend is represented by the improvement in hygienic condition and food quality control. These results present an argument for continuing the TORCH screening of pregnant women.


2017 ◽  
Vol 90 ◽  
pp. 14-17 ◽  
Author(s):  
Marie-Luce Delforge ◽  
Elena Costa ◽  
Françoise Brancart ◽  
Deborah Goldman ◽  
Isabel Montesinos ◽  
...  

Author(s):  
V.N. Demidov, A.I. Gus, T.A. Yarygina

Our statistical analysis, based on ultrasound examination of 7069 pregnant women, showed that both in the absence and in the presence of a scar on the uterus in the region of its lower segment, the placenta in the 3rd trimester of pregnancy was located extremely rarely, only in 0.1%. It was either primarily located in other parts of the uterus, or migrated from the lower segment of the uterus towards the bottom. In the case of the location of the placenta in this area, its ingrowth was not observed only in 2.3% of women. The main ultrasound signs of ingrowth of the placenta into the scar was the absence of its migration, as well as the presence of a combination of placenta previa with its localization in the scar zone. From the data obtained, it follows that the sensitivity of ultrasound diagnosis of placental accreta was 97.7%, and the specificity was 99.9%. According to our data, ingrown placenta in most cases can be delivered as early as 14–19 weeks, and the time spent on detecting this pathology usually does not exceed one minute.


Sports ◽  
2019 ◽  
Vol 7 (12) ◽  
pp. 245 ◽  
Author(s):  
Bo Tillander ◽  
Håkan Gauffin ◽  
Johan Lyth ◽  
Anders Knutsson ◽  
Toomas Timpka

There is a need for clinical indicators that can be used to guide the treatment of Achilles tendon complaints in recreational runners. Diagnostic ultrasound has recently been introduced for clinical decision support in tendon pain management. The aim of this study was to determine whether tendon thickness and morphological changes in the Achilles tendon detected in ultrasound examinations are associated with local symptoms in middle-age recreational long-distance runners. Forty-two Achilles tendons (21 middle-aged runners) were investigated by ultrasound examination measuring tendon thickness and a morphology score indicating tendinosis. The Generalized Estimating Equations method was applied in multiple models of factors associated with reporting a symptomatic tendon. Eleven symptomatic and 31 asymptomatic Achilles tendons were recorded. In the multiple model that used tendon thickness measured 30 mm proximal to the distal insertion, an association was found between thickness and reporting a symptomatic tendon (p < 0.001; OR 12.9; 95% CI 3.1 to 53.2). A qualitative morphology score was not found to be significantly associated with reporting a symptomatic tendon (p = 0.10). We conclude that symptomatic Achilles tendons were thicker than asymptomatic tendons on ultrasound examination among recreational long-distance runners and that the importance of parallel morphological findings need to be further investigated in prospective studies.


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