scholarly journals A Clinical Study on Sleshmala Yonivyapad through Anubhoota Yoga the ‘Patrangadi Yoga’

2021 ◽  
Vol 11 (10) ◽  
pp. 109-117
Author(s):  
Shweta Sindagi ◽  
Savita Sajjan ◽  
Anita Halagatti
Keyword(s):  
Trichomonas Vaginalis ◽  
Signs And Symptoms ◽  
Complete Relief ◽  
Partial Relief ◽  
Appropriate Treatment ◽  
Before And After ◽  
Effect Of Therapy ◽  
Chief Complaints ◽  
Foul Smell

Sleshmala yonivyapad is one of the most common and burning problem faced by the women all around the globe. The symptoms are vaginal white discharge, itching, foul smell mild pain in vagina. On the bases of chief complaints and review of the disease the shlesmala yonivyapat is compared with Trichomonas vaginalis. There are many treatments prescribed for this problem but they are not free from side effects and with reoccurrence. Hence selection of an appropriate treatment is very essential. Study design: In the present study, 30 patients fulfilling criteria of sleshmala yonivyapat were selected under single group. Patients were given Patrangadi churna 4gms thrice a day with ushnodaka internally after food for 7 days and Yoniprakshalana with Patrangadi kashaya for 7days. This study was carried out for 21 days. The signs and symptoms were observed before and after treatment and were compared. Subjective parameters: Picchila shweta srava, Dourgandya, Kandu and Alpavedana. Objective parameters: Profuse thick creamy discharge, Red and swollen vulva with evidence of pruritis like scratch marks and wet mount showing Trichomonas vaginalis positive. Result: In the present study total 11 subjects showed complete relief, 17 subjects showed moderate relief and 2 subjects showed partial relief after treatment. And 11 subjects showed complete relief, 7 subjects showed moderate relief, 7 subjects showed partial relief and 5 subjects showed no relief after follow up. The total effect of therapy provided statistically highly significant result (p<0.001) in both subjective and objective parameters. Paired ‘t’ test is applied. Thus the study showed the effectiveness of Patrangadi churna internally as well as Patrangadi kashaya yoniprakshalana in alleviating symptoms of sleshmala yonivyapad. Key words: Sleshmala yonivyapad, Patrangadi yoga, Trichomonas vaginalis.

scholarly journals AB0571 IS RITUXIMAB AN ADEQUATE GLUCOCORTICOID SPARING AGENT IN IDIOPATHIC INFLAMMATORY MYOPATHIES?

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1582.1-1582
Author(s):  
B. H. Egeli ◽  
S. Ergun ◽  
Y. K. Gursoy ◽  
A. Cetin ◽  
S. Ugurlu
Keyword(s):  
Disease Activity ◽  
Alternative Treatment ◽  
Statistical Power ◽  
Signs And Symptoms ◽  
Small Sample ◽  
Idiopathic Inflammatory Myopathies ◽  
Inflammatory Myopathies ◽  
Treatment Methods ◽  
Before And After

Background:Idiopathic inflammatory myopathies (IIM) are essentially treated aiming improvement of muscle function and extra muscular disease manifestations. The backbone of the treatment is corticosteroids enhancing the survival and patient quality of life. The lack of consensus on target-specific immunosuppressive treatment highlights the need for further studies evaluating alternative treatment methods. Rituximab is potentially a glucocorticoid-sparing agent which was reviewed in multiple studies with small sample sizes due to the rarity of the disease.Objectives:Higher statistical power can enhance the trustworthiness of alternative treatment methods yielding the main objective of this study.Methods:This retrospective study was conducted at a tertiary rheumatology center. Patients were diagnosed with an idiopathic inflammatory myopathy (dermatomyositis [DM], polymyositis [PM]) and were treated with rituximab in order to be included in this study. Clinical signs and symptoms of the presentation were noted during the first patient encounter as well as the follow-up. Parameters of disease activity including acute phase reactants, muscle enzyme levels, and disease-specific autoantibodies were analyzed.Results:The study includes 28 patients (20 DM, 8 PM). The age of diagnosis was 43.44 ± 15.77 years, follow-up duration was 60.7 ± 70.7 months. The presenting signs and symptoms of the patients are shown in Figure 1. The parameters of disease activity before and after treatment are summarized in Table 1. The mean corticosteroid dose decreased from 31.429 ±23.934 mg to 10.278 ±12.001 (p=0.001). Other treatment methods were methotrexate (n=18), Intravenous Immunoglobulin (IVIG) (n=7), and cyclophosphamide (n=2). There were not any deaths during the follow-up. Two patients were lost to follow-up.Table 1.The Parameters of Disease Activity Before and After TreatmentBefore TreatmentAfter TreatmentP ValueCPK, mean ± std (U/L)1426 ± 2049.92263.44 ± 265.630.004LDH, mean ± std (U/L)557.5 ± 365379.78 ± 192.10.03AST, mean ± std (U/L)62.52 ± 5930.16 ± 27.590.01ALT, mean ± std (U/L)56.48 ± 49.2127.64 ± 24.520.008ESR, mean ± std (mm/hour)26.38 ± 28.9820.39 ± 18.760.36CRP, mean ± std (mg/L)19.23 ± 46.1512.53 ± 26.670.5RF, mean ± std (U/mL)0 (0)N/AN/AANA, n (%)3 (10.71)N/AN/AFigure 1.The Presenting Signs and Symptoms of the PatientsConclusion:Rituximab is shown to be effective in treating myositis along with corticosteroids as well as a corticosteroid-sparing agent in retrospective studies and open-label clinical trials; however, lack of statistical power should be underlined. Long term decrease in steroid use and decrease in disease activity markers hints the effective use of rituximab as a glucocorticoid sparing agent as well as its safety with minimal side effects.Disclosure of Interests:None declared

scholarly journals Role of Radiotherapy in Recurrent Intra-Abdominal Yolk Sac Tumor

2021 ◽  
pp. 1010-1018
Author(s):  
Marhendra Satria Utama ◽  
Andi Kurniadi ◽  
A.A. Citra Yunda Prahastiwi ◽  
Antony A. Adibrata
Keyword(s):  
Case Reports ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Appropriate Treatment ◽  
Curative Radiotherapy ◽  
Chief Complaints ◽  
Abdominal Mri ◽  
Malignant Germ Cell Tumor

Yolk sac tumor (YST) is a rare malignant germ cell tumor with no appropriate treatment strategy to date. However, patients are treated on a case-to-case basis as per various case reports that have been published. Here, we present a case of 27-year-old female patient who presented to us with chief complaints of severe abdominal pain associated with leucorrhea. She previously had a similar pain episode, which was then evaluated by a multidisciplinary team. She was diagnosed with YST. After that, she underwent 6 cycles of chemotherapy, but there was no improvement. Then the medical oncologist referred her to performed radiotherapy. Then, the radiation oncologist decided to give her curative radiotherapy of 3D-CRT. After completing her sessions, she felt better and clinically improving. After that, she was discharged and scheduled a follow-up visit for first evaluation. At her follow-up visit, she was feeling well, and we decided to have an abdominal MRI.

scholarly journals Does immunological remission, defined as disappearance of autoantibodies, occur with current treatment strategies? A long-term follow-up study in rheumatoid arthritis patients who achieved sustained DMARD-free status

2019 ◽  
Vol 78 (11) ◽  
pp. 1497-1504 ◽  
Author(s):  
Debbie M Boeters ◽  
Leonie E Burgers ◽  
René EM Toes ◽  
Annette van der Helm-van Mil
Keyword(s):  
Rheumatoid Arthritis ◽  
Treatment Strategies ◽  
Signs And Symptoms ◽  
Current Treatment ◽  
Dmard Therapy ◽  
Before And After ◽  
Long Term Follow Up ◽  
Free Status

ObjectivesSustained disease-modifying antirheumatic drug (DMARD)-free status, the sustained absence of synovitis after cessation of DMARD therapy, is infrequent in autoantibody-positive rheumatoid arthritis (RA), but approximates cure (ie, disappearance of signs and symptoms). It was recently suggested that immunological remission, defined as disappearance of anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF), underlies this outcome. Therefore, this long-term observational study determined if autoantibodies disappear in RA patients who achieved sustained DMARD-free remission.MethodsWe studied 95 ACPA-positive and/or RF-positive RA patients who achieved DMARD-free remission after median 4.8 years and kept this status for the remaining follow-up (median 4.2 years). Additionally, 21 autoantibody-positive RA patients with a late flare, defined as recurrence of clinical synovitis after a DMARD-free status of ≥1 year, and 45 autoantibody-positive RA patients who were unable to stop DMARD therapy (during median 10 years) were studied. Anti-cyclic citrullinated peptide 2 (anti-CCP2) IgG, IgM and RF IgM levels were measured in 587 samples obtained at diagnosis, before and after achieving DMARD-free remission.Results13% of anti-CCP2 IgG-positive RA patients had seroreverted when achieving remission. In RA patients with a flare and persistent disease this was 8% and 6%, respectively (p=0.63). For anti-CCP2 IgM and RF IgM, similar results were observed. Evaluating the estimated slope of serially measured levels revealed that RF levels decreased more in patients with than without remission (p<0.001); the course of anti-CCP2 levels was not different (p=0.66).ConclusionsSustained DMARD-free status in autoantibody-positive RA was not paralleled by an increased frequency of reversion to autoantibody negativity. This form of immunological remission may therefore not be a treatment target in patients with classified RA.

Conjunctivitis

2022 ◽  
pp. 53-101
Keyword(s):  
Clinical Signs ◽  
Stable Condition ◽  
Signs And Symptoms ◽  
Cellular Infiltration ◽  
Ligneous Conjunctivitis ◽  
Appropriate Treatment ◽  
Before And After ◽  
Clinical Signs And Symptoms ◽  
Basic Approaches

Conjunctivitis represents an inflammation of conjunctiva with cellular infiltration, exudation, and vascular dilation. According to the course of the disease, conjunctivitis can be acute, hyperacute, and chronic. Morphologically, conjunctivitis can appear with papillary reaction, follicular reaction, cicatrizing, granulomatous and membranous changes. This chapter discusses all types of conjunctivitis, their clinical signs and symptoms, and basic approaches of treatment. This chapter includes before and after treatment photos of atypical inferiorly localized shield ulcer, Tularemia-associated Parinaud oculoglandular syndrome, and Stevens-Johnson disease. Pictures are included In the ligneous conjunctivitis patient's case taken at diagnosis as well as 10 years later, demonstrating stable condition with appropriate treatment throughout the period.

scholarly journals EARLY COMPLICATIONS IN BARIATRIC SURGERY:

2013 ◽  
Vol 50 (1) ◽  
pp. 50-55 ◽  
Author(s):  
Marco Aurelio SANTO ◽  
Denis PAJECKI ◽  
Daniel RICCIOPPO ◽  
Roberto CLEVA ◽  
Flavio KAWAMOTO ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Severe Obesity ◽  
Gastric Bypass Surgery ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Early Postoperative Period ◽  
Morbidly Obese ◽  
Early Complications ◽  
Appropriate Treatment

ContextBariatric surgery has proven to be the most effective method of treating severe obesity. Nevertheless, the acceptance of bariatric surgery is still questioned. The surgical complications observed in the early postoperative period following surgeries performed to treat severe obesity are similar to those associated with other major surgeries of the gastrointestinal tract. However, given the more frequent occurrence of medical comorbidities, these patients require special attention in the early postoperative follow-up. Early diagnosis and appropriate treatment of these complications are directly associated with a greater probability of control.MethodThe medical records of 538 morbidly obese patients who underwent surgical treatment (Roux-en-Y gastric bypass surgery) were reviewed. Ninety-three (17.2%) patients were male and 445 (82.8%) were female. The ages of the patients ranged from 18 to 70 years (average = 46), and their body mass indices ranged from 34.6 to 77 kg/m2.ResultsEarly complications occurred in 9.6% and were distributed as follows: 2.6% presented bleeding, intestinal obstruction occurred in 1.1%, peritoneal infections occurred in 3.2%, and 2.2% developed abdominal wall infections that required hospitalization. Three (0.5%) patients experienced pulmonary thromboembolism. The mortality rate was 0,55%.ConclusionThe incidence of early complications was low. The diagnosis of these complications was mostly clinical, based on the presence of signs and symptoms. The value of the clinical signs and early treatment, specially in cases of sepsis, were essential to the favorable surgical outcome. The mortality was mainly related to thromboembolism and advanced age, over 65 years.

scholarly journals ADD ON EFFECT OF GR̥ ÑJANAKA PĒYA ALONG WITH A THERAPEUTIC DIETARY PROTOCOL IN RAKTĀRŚAḤ (BLEEDING PILE) – A NON-RANDOMIZED CONTROLLED TRIAL

2021 ◽  
Vol 9 (7) ◽  
pp. 1393-1397
Author(s):  
Bindu K.T ◽  
Shobhana M. C. ◽  
Prema P. E
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Study Group ◽  
Randomized Controlled ◽  
Therapeutic Protocol ◽  
Before And After ◽  
Clinical Signs And Symptoms

A non-randomized controlled trial was carried out in 40 participants with intervention for 15 days and a follow up of 7 days. Clinical signs and symptoms of raktārśaḥ were assessed before and after the intervention and after fol- lowing up, by using the subjective parameters scale including, Frequency of bleeding, Nature of bleeding, Change in colour of the mucosa of pile mass, Character of defecation and Period of straining. Grñjanaka pēya along with a therapeutic protocol in raktārśaḥ has shown significant positive changes in subjective parameters like frequency of bleeding (p<0.01 level), nature of bleeding (p<0.01 level), changes in the mucosa, period of straining and char- acter of defecation after the 15 days of intervention in the study group. Keywords: Raktārśaḥ, Gr̥ ñjanaka pēya, Therapeutic dietary protocol, Subjective parameters

Effects of an educational program in increasing knowledge and reducing premenstrual syndrome signs, symptoms and severity among nursing college students

2016 ◽  
Vol 5 (4) ◽  
pp. 200
Author(s):  
Nafisa Abdalla ◽  
Mohammed Gibreel
Keyword(s):  
Education Program ◽  
Premenstrual Syndrome ◽  
Educational Program ◽  
Signs And Symptoms ◽  
Study Group ◽  
Significant Difference ◽  
Before And After ◽  
Increasing Knowledge ◽  
Nursing College

Objective: The objective of the following study is to determine the effects of an Educational Program in increasing knowledge and reducing premenstrual syndrome symptoms and severity among nursing college students.Material and Methods: A total of 60 students with Premenstrual Syndrome (PMS) symptoms were included in the study group (n=60), the age of the majority of them (75.8%) was between 20-24 years, pre and post education program questionnaire was developed as a tool of data collection before and after the educational program. Also premenstrual symptoms and severity follow-up sheet was designed and conducted three month after the post education program to follow the effectiveness of the educational program in reducing the severity of the symptoms.Results: The study results indicate that there was significant difference between students’ knowledge before and after the program, the total score mean rank before program was (34.72), while after program was (86.28) p < 0.01 with significant difference between score before and after the program at 1% level of significant. It also shows a significant difference between PMS signs, symptoms and severity before and after program at 1% level of significant (total score mean and SD before program were (132.42, 13.72) respectively, and after program are (107.52, 14.47) respectively p < 0.01 with larger effect size of 0.613. The follow-up result shows a reduction in PMS symptom’s severity, the total severity averages of PMS sign and symptoms were 3.4 first month, 2.6 the second month and 2.2 for the third month out of 4 respectively.Conclusion: The educational program had a positive effect on increasing knowledge and decreasing PMS signs and symptoms severity. Also the program has decrease the effect of PMS signs and symptoms on study group life.

scholarly journals Orthodontic Treatment Including Autotransplantation of a Mature Tooth

2009 ◽  
Vol 79 (2) ◽  
pp. 387-393 ◽  
Author(s):  
Kazuaki Nishimura ◽  
Shinobu Amano ◽  
Kimihisa Nakao ◽  
Shigemi Goto
Keyword(s):  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Root Resorption ◽  
Treatment Plan ◽  
Primary School Student ◽  
Appropriate Treatment ◽  
Japanese Female ◽  
Old Japanese ◽  
Chief Complaints

Abstract The patient was a 24-year-old Japanese female. The chief complaints were crowding and masticatory dysfunction due to the missing right first molar. Her maxillary first premolars had been extracted when she was a primary school student. We planned orthodontic treatment with extraction of the mandibular first premolars and transplantation of the mandibular left first premolar into the maxillary right first molar area. We made a diagnostic setup model to initiate an appropriate treatment plan for the discrepancy in tooth size ratio. Following the diagnostic setup model, the space in the maxillary right first molar area was closed by a small amount of tooth movement, and a good occlusion was achieved. The patient had been in retention for 7 years, and the occlusion has been maintained very well during this time. In the follow-up, 10 years after autotransplantation, no signs of inflammatory or replacement root resorption were found, and marginal bone support appeared similar to that of neighboring teeth.

scholarly journals Management of Vataja Kasa w.s.r. to Tropical Pulmonary Eosinophilia by Shringarabhra Rasa with Mridu Virechana

2021 ◽  
pp. 508-513
Author(s):  
Sridevi. P. Kulkarni ◽  
Sourabh Gupta ◽  
P. G. Subbannagowda
Keyword(s):  
Adverse Effects ◽  
Signs And Symptoms ◽  
Hot Water ◽  
Pulmonary Eosinophilia ◽  
Blood Eosinophilia ◽  
Effect Of Therapy ◽  
Males And Females ◽  
Ayurvedic Treatment ◽  
Peripheral Blood Eosinophilia

The clinical features of vataja kasa are oftenly compared to TPE are, Shushka kasa, Alpa kapha nishtivana, Swarabedha, shushka ura kantha vaktrata, Dourbalya etc. TPE is an occult form of filariasis and is characterized by dry cough, dyspnoea, nocturnal wheezing etc, and marked peripheral blood eosinophilia. This affects males and females at a ratio of 4:1 often during the 3rd decade of life. Keeping in view about the adverse effects of the modern sciences, an attempt was made to find an effective Ayurvedic treatment modality. Methods: 15 subjects with classical signs and symptoms of Vataja kasa and raised esinophil count >500cells/cumm were selected. After Amapachana by Shunti churna with hot water, subjects were given Kantakari ghrita for Snehapana prior to Virechana with Eranda taila followed by Shringarabhra rasa for 21 days with follow up of 1 month. Results: Shringarabhra Rasa with Mridu Virechana provided highly significant results in all parameters of assessment. Conclusion:  It is found that the relief was highly significant after Mridu Virechana. It is found that the effect of therapy was highly significant on Shushka kasa and Shushka urah kantha vaktra.

Long-term Follow-up of the Green-Watermann Osteotomy for Hallux Limitus

2002 ◽  
Vol 92 (10) ◽  
pp. 543-554 ◽  
Author(s):  
Jason B. Dickerson ◽  
Richard Green ◽  
Donald R. Green
Keyword(s):  
Clinical Evaluation ◽  
Average Length ◽  
Metatarsophalangeal Joint ◽  
First Metatarsophalangeal Joint ◽  
Hallux Limitus ◽  
Before And After ◽  
Chief Complaints ◽  
Long Term Follow Up

The authors undertook a retrospective analysis of the long-term efficacy of the Green-Watermann procedure for the treatment of painful hallux limitus or rigidus. Questionnaires were sent to 80 consecutive patients who had such procedures performed between 1990 and 1999. Medical records and radiographs were reviewed for the 32 patients who completed the questionnaires, representing 40 Green-Watermann procedures. Twenty-four patients were able to return for clinical evaluation. The average length of follow-up was 4 years (range, 1 to 10 years). The questionnaires addressed pain before and after surgery, function after surgery, complications, and overall impression and satisfaction. Nearly all of the patients (30 of 32; 94%) reported that surgery had significantly relieved their hallux joint pain, and a slightly smaller proportion (28 of 32; 88%) felt that their chief complaints were at least 70% improved. Clinical evaluation revealed adequate range of motion at the first metatarsophalangeal joint. It is concluded that the Green-Watermann procedure is an effective treatment approach for hallux limitus and rigidus, resulting in a significant reduction in pain, an increase in function, and a high degree of patient satisfaction. (J Am Podiatr Med Assoc 92(10): 543-554, 2002)

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