One of the reasons for the unprofi tability of dairy cattle breeding is fasciolose invasion. This disease can cause signifi cant economic damage in the form of a decrease in the milk production of cows, a decrease in the growth of young animals and a negative impact on the reproduction and renewal of the herd. The domestic veterinary market is saturated with a large number of various anti-trematode drugs of both foreign and domestic production, however, the price/eff ectiveness of anthelmintics remains a key aspect for animal owners. However, against parasitic drugs, they only destroy the parasite in the body of sick animals, without pouring in on the processes of recovery of the body after invasion. Longterm use of the same drugs, violation of the instructions for use of the latter leads to an increase in the number of reports of scientists from around the world about the increase in the number of cases of development of fasciol resistance in anthelmintics. That is why the search and testing of new therapeutic combinations that ensure the release of cattle from trematodes and helped restore disturbed physiological functions remain relevant today. The study presents the results of testing the use of a combination of rafenzene emulsion and infusion of St. John's wort on cattle fascioliasis in the conditions of the dairy industry of the Kyiv region. The purpose of the study was to study the therapeutic effi cacy of a combination of aetiotropic and pathogenetic therapies of calves for fasciulosis - rafenzol emulsion and infusion of herbs with St. John's wort. The young cattle of the black-bred breed, aged 12-18 months, were examined and their faeces sampled. The calves were monitored for 30 days during the experiment. They paid attention to the general condition. Heart rate, body temperature and respiratory rate were measured. Studies of individual organs and systems were performed according to conventional methods. Coprological studies were performed on the 10th and 30th day of observation. Used the method of sequential fl ushing faces. Calves, one of which was a control, was formed to study the eff ectiveness of antitrematodes measures. In each of them there were 5 animals, aff ected by fascioles, selected on the principle of analogues. The calves of the fi rst group were administered rafenzol emulsion at a dose of 0.75 ml of the preparation per 10 kg of body weight inside once, the animals of group 2 used the drug similar to the fi rst group. Previously they were fed with infusion of herbs St. John's wort. The control group was not treated.The results of the study indicate that the young is large aff ected with fascioles and the average invasion intensity is 48% and the intensity is 17 copies of eggs, respectively. Complex use of rafenzol emulsion with infusion of herbs with St. John's wort, according to the scheme, after 80 days revealed 80% of the extent and intensity. After 30 days, the indicator improved to 100%. Extensibility and intensifi cation of one rafenzol emulsion, after 10 days was 40%, for 30 days the effi ciency increased to 80%. St. John's wort improves the regeneration of tissue-damaged fasciolosis. It contributes to the absorption of feed and restore productivity. Therefore, treatment and prevention of fasciulosis in the farm is best done comprehensively.
Key words: rafenzene emulsion, st. John's wort herb infusion, fasciolosis, disease intensity and intensity, effi cacy and drug intensity.
Integrated treatment of cattle in fasсiolosis
