Acid Catalyzed Synthesis of substituted-n-((1, 3-diphenyl-1h-pyrazol-4-yl) methyl) benzenamine
Keyword(s):
A new derivative synthesis of Substituted-N-((1, 3-diphenyl-1h-pyrazol-4-yl) methyl) benzenamine has attempted by using commonly available key starting materials Acetophenone (1) and substituted phenyl hydrazine in presence of sulfuric acid catalyst and alcohol solvent to afford potential antiviral active analogues. The synthesis proceeds through Vilsmeier-Haack reaction followed by reductive amination by using sodium borohydride.
Efficient hydrogen generation from sodium borohydride hydrolysis using silica sulfuric acid catalyst
2015 ◽
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1984 ◽
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1973 ◽
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Vol 2094
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pp. 052043