A case report of extensive cerebral venous sinus thrombosis: a sequela of COVID-19?

2021 ◽  
Vol 20 (3) ◽  
pp. 219-222
Author(s):  
S Sivalokanathan ◽  
◽  
MO Syed ◽  
A Sharmila ◽  
◽  
...  
Keyword(s):  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Low Molecular Weight ◽  
Diagnostic Challenge ◽  
Venous Sinus Thrombosis ◽  
Refractory Headache ◽  
Thrombotic Complications ◽  
Medical Intensive Care ◽  
Persistent Headache

Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease that is often the trigger for thrombotic complications. Cerebral venous sinus thrombosis (CVST) represents a small percentage of strokes, frequently proving to be a diagnostic challenge. We report a 31-year-old lady presenting with a persistent headache, 18 weeks after a mild COVID-19 illness. On her second visit, CT venography revealed extensive CVST. She was commenced on low-molecular-weight heparin, and was monitored closely in the neuro-medical intensive care unit. She was discharged 2 weeks later, with no residual neurological deficit, and commenced on a direct oral anticoagulant in the community. CVST should be considered in patients presenting with a refractory headache, with greater suspicion if previously infected with SARS-CoV-2.

scholarly journals Cerebral Venous Sinus Thrombosis with an Intracranial Haemorrhage: A Case Report

2019 ◽  
Vol 7 (6) ◽  
pp. 1029-1031 ◽  
Author(s):  
Abdullah M. Al Zahrani ◽  
Reem Al Sheikh
Keyword(s):  
Sinus Thrombosis ◽  
Signs And Symptoms ◽  
Cerebral Venous Sinus Thrombosis ◽  
Pregnant Female ◽  
Venous Sinus ◽  
Diagnostic Challenge ◽  
Venous Sinus Thrombosis ◽  
Sagittal Sinus ◽  
Life Threatening ◽  
Acute Headache

BACKGROUND: Cerebral venous sinus thrombosis (CVST) is a rare, life-threatening disorder. It has an annual incidence of approximately two to four per million people per year. Nearly 70–80% of all cases of CVST are located in the superior sagittal sinus (SSS). CVST presents a diagnostic challenge due to different presentations. CASE PRESENTATION: We describe the case of a young pregnant female who presented to the emergency room with an acute headache attributed to multifactorial causes. CONCLUSION: This report highlights the importance of including CVST in the differential diagnosis when treating a pregnant female with headaches. Although the symptoms of CVST are varied, the most common occlusion is in the SSS. In such cases, the patient may present with signs and symptoms that include headaches, intracranial hypertension and papilloedemas.

scholarly journals Extensive cerebral venous sinus thrombosis: a potential complication in a patient with COVID-19 disease

2020 ◽  
Vol 13 (8) ◽  
pp. e236820 ◽  
Author(s):  
Paul Bolaji ◽  
Babatunde Kukoyi ◽  
Nasar Ahmad ◽  
Chris Wharton
Keyword(s):  
Sinus Thrombosis ◽  
Inpatient Rehabilitation ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Pulmonary Vasculature ◽  
Venous Sinus Thrombosis ◽  
Ventilation Imaging ◽  
Potential Association ◽  
Thrombotic Complications ◽  
Recent Diagnosis

A 63-year-old man was admitted with left-sided weakness and subsequent focal seizures following a recent diagnosis of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in a nearby hospital. He developed status epilepticus and became comatose, requiring intensive care unit admission for invasive ventilation. Imaging done at admission confirmed extensive cerebral venous sinus thrombosis (CVST) with bilateral venous cortical infarcts and acute cortical haemorrhage. No known risk factor for CVST could be identified. He improved with anticoagulation and antiepileptic therapy. He was subsequently transferred to an inpatient rehabilitation facility. Although Coronavirus disease 19 (COVID-19) infection has been previously associated with thrombotic complications, these mostly relate to the pulmonary vasculature. We present this case as a potential association between CVST and COVID-19 infection.

scholarly journals Cerebral Venous Sinus Thrombosis: A Case Report

2015 ◽  
Vol 3 (1) ◽  
pp. 39-41
Author(s):  
Debasish Kumar Saha ◽  
ASM Areef Ahsan ◽  
Mohammad Omar Faruq ◽  
Kaniz Fatema ◽  
Fatema Ahmed ◽  
...  
Keyword(s):  
Case Report ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Severe Headache ◽  
Predisposing Factors ◽  
Venous Sinus ◽  
Diagnostic Challenge ◽  
Venous Sinus Thrombosis ◽  
Dangerous Condition

Cerebral venous sinus thrombosis (CVST) is a rare but dangerous condition occurring with an incidence of 3-4 cases per million per year. CVST presents a diagnostic challenge due to its varied presentation pattern. Here we report a case of a 40 year old diabetic, male, presenting with sudden severe headache with quadriplegia, where two predisposing factors were found.Bangladesh Crit Care J March 2015; 3 (1): 39-41

scholarly journals Cerebral Venous Sinus Thrombosis in Early Pregnancy : A Case Report

2019 ◽  
Vol 18 (1) ◽  
pp. 54-56
Author(s):  
Salma Akhter
Keyword(s):  
Sinus Thrombosis ◽  
Post Partum ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Low Molecular Weight ◽  
Contributing Factors ◽  
Venous Sinus Thrombosis ◽  
Mother And Child ◽  
Uncommon Condition ◽  
Neuro Imaging

Cerebral Venous Sinus Thrombosis (CVST) in pregnancy is an uncommon condition and affects about 5 women per million. Actual etiology is difficult to confirm, a hypercoagulable state along with protein Sand C deficiency, hyperhomocystinaemia are the contributing factors. MRV like neuro imaging is the main stay of diagnosis. Treatment with Low molecular weight heparin throughout the pregnancy and post partum period can save the life of both mother and child. Chatt Maa Shi Hosp Med Coll J; Vol.18 (1); Jan 2019; Page 54-56

scholarly journals Cerebral Venous Sinus Thrombosis Associated with SARS-CoV-2; a Multinational Case Series

2020 ◽  
Author(s):  
Ashkan Mowla ◽  
Banafsheh Shakibajahromi ◽  
Shima Shahjouei ◽  
Afshin Borhani-Haghighi ◽  
Nasrin Rahimian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sinus Thrombosis ◽  
Case Series ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Control Group ◽  
Inclusion Criteria ◽  
Venous Sinus Thrombosis ◽  
Cortical Vein ◽  
Thrombotic Complications

Background: SARS-CoV-2 induced coagulopathy can lead to thrombotic complications such as stroke. Cerebral venous sinus thrombosis (CVST) is a less common type of stroke which might be triggered by COVID-19. We present a series of CVST cases with SARS-CoV-2 infection. Methods: In a multinational retrospective study, we collected all cases of CVST in SARS-CoV-2 infected patients admitted to nine tertiary stroke centers from the beginning of the pandemic to June 30th, 2020. We compared the demographics, clinical and radiological characteristics, risk factors, and outcome of these patients with a control group of non-SARS-CoV-2 infected CVST patients in the same seasonal period of the years 2012-2016 from the country where the majority of cases were recruited. Results: A total of 13 patients fulfilled the inclusion criteria (62% women, mean age 50.9 years). Six patients were discharged with good outcomes (mRS≤2) and three patients died in hospital. Compared to the control group, the SARS-CoV-2 infected patients were significantly older (50.9 versus 36.7 years, p<0.001), had a lower rate of identified CVST risk factors (23.1% versus 84.2%, p<0.001), had more frequent cortical vein involvement (38.5% versus 10.5%, p: 0.025), and a non-significant higher rate of in-hospital mortality (23.1% versus 5.3%, p: 0.073). Conclusion: CVST should be considered as potential comorbidity in SARS-CoV-2 infected patients presenting with neurological symptoms. Our data suggest that compared to non-SARS-CoV-2 infected patients, CVST occurs in older patients, with lower rates of known CVST risk factors and might lead to a poorer outcome in the SARS-CoV-2 infected group.

scholarly journals Cerebral Venous Sinus Thrombosis (CVST): an emerging complication of SARS CoV-2 infection

2021 ◽  
Author(s):  
Nicola Maggialetti ◽  
GUALANO ALESSANDRA ◽  
Roberto Russo ◽  
Rocco Umberto Accogli ◽  
Amato Antonio Stabile Ianora
Keyword(s):  
Emergency Department ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Neurological Symptoms ◽  
Venous Sinus ◽  
Thrombotic Complication ◽  
Virus Binding ◽  
Case Presentation ◽  
Venous Sinus Thrombosis ◽  
Thrombotic Complications

Abstract Background: During Coronavirus (COVID-19) pandemic, SARS CoV-2 infection has been documented to be associated with thrombotic complications, especially pulmonary embolism, which are triggered by virus binding to ACE-2 receptors and consequent activation of a cascade leading to a hypercoagulable pathway, however Cerebral Venous Sinus Thrombosis (CVST) is emerging as a further thrombotic complication of COVID-19.Case presentation: We report our experience of a patient affected by SARS CoV-2 infection, who presented to our emergency department with neurological symptoms such as confusion and headache and was diagnosed with CVST at imaging exams.Conclusion: As neurological symptoms such as confusion and headache are aspecific and shared with patients affected by SARS CoV-2 infection in absence of CVST, clinicians should be aware of this emerging hematologic complication in order to recognize it as soon as possible and provide the best patient care.

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